Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Gerlinde Reim"'
Publikováno v:
PLoS Biology, Vol 12, Iss 11, p e1001988 (2014)
The Wingless (Wg/Wnt) signaling pathway is essential for metazoan development, where it is central to tissue growth and cellular differentiation. Deregulated Wg pathway activation underlies severe developmental abnormalities, as well as carcinogenesi
Externí odkaz:
https://doaj.org/article/77a6bccc0bdd4832b06d2e7bf59c3ef5
Publikováno v:
Mechanisms of development
Mechanisms of Development
Mechanisms of Development
Sphingolipids are an important part of the plasma membrane and implicated in a multitude of cellular processes. However, little is known about the role of sphingolipids in an epithelial context and their potential influence on the activity of signali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9276b7ca7b2a8e1bfe9f8e8e590a1bff
https://doi.org/10.1016/j.mod.2013.04.001
https://doi.org/10.1016/j.mod.2013.04.001
Autor:
Gerlinde Reim, Michael Brand
Publikováno v:
Development. 133:2757-2770
Dorsoventral (DV) axis formation of the vertebrate embryo is controlled by the maternal genome and is subsequently refined zygotically. In the zygote,repression of ventralizing Bmp activity on the dorsal side through chordin and noggin is crucial for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df1270c9d39290ad9db37b43a758f823
https://doi.org/10.1242/dev.02391
https://doi.org/10.1242/dev.02391
Publikováno v:
Development. 129:905-916
In early embryonic development, the brain is divided into three main regions along the anteroposterior axis: the forebrain, midbrain and hindbrain. Through retroviral insertional mutagenesis and chemical mutagenesis experiments in zebrafish, we have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53aa64729ff40681e0aa9756232e4e81
https://doi.org/10.1242/dev.129.4.905
https://doi.org/10.1242/dev.129.4.905
Publikováno v:
PLoS Biology
PLoS Biology, Vol 12, Iss 11, p e1001988 (2014)
PLoS Biology, Vol 12, Iss 11, p e1001988 (2014)
This study uses an RNAi screen in Drosophila to identify a UBX protein, Armless, as a novel positive regulator of the important Wingless/Wnt signaling pathway, acting to stabilize Armadillo/?-Catenin by antagonizing its turnover.
The Wingless (W
The Wingless (W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f122a5789387818116c9571e3e29ead7
Publikováno v:
Mechanisms of Development. 126
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0395557ae3367bde087564685a7761ee
Publikováno v:
Developmental cell. 6(1)
The gastrulating vertebrate embryo develops three germlayers: ectoderm, mesoderm, and endoderm. Zebrafish endoderm differentiation starts with the activation of sox17 by casanova (cas). We report that spg (pou2/Oct4) is essential for endoderm formati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ba9a7e6ecffdfa63663918cefcb676c
https://pubmed.ncbi.nlm.nih.gov/14723850
https://pubmed.ncbi.nlm.nih.gov/14723850
Autor:
Michael Brand, Gerlinde Reim
Publikováno v:
Development (Cambridge, England). 129(4)
Neural patterning of the vertebrate brain starts within the ectoderm during gastrulation and requires the activity of organizer cell populations in the neurectoderm. One such organizer is located at the prospective midbrain-hindbrain boundary (MHB) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::807768677ad74f9d991faa8edc22ca83
https://pubmed.ncbi.nlm.nih.gov/11861475
https://pubmed.ncbi.nlm.nih.gov/11861475
Autor:
Marina Pasca di Magliano, Meinrad Busslinger, Peter L. Pfeffer, Gerlinde Reim, Bernhard Payer
Publikováno v:
Development (Cambridge, England). 129(2)
Pax2 is the earliest known gene to be expressed throughout the mid-hindbrain region in late gastrula embryos of the mouse and is essential for the formation of an organizing center at the midbrain-hindbrain boundary (MHB), which controls midbrain and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d367efbc772ff9669722cc0192795632
https://pubmed.ncbi.nlm.nih.gov/11807024
https://pubmed.ncbi.nlm.nih.gov/11807024
Autor:
Gerlinde, Reim, Michael, Brand
Publikováno v:
Development; February 2002, Vol. 129 Issue: 4 p917-33, 17p