Zobrazeno 1 - 10
of 137
pro vyhledávání: '"Gerlinde R Van de Walle"'
Autor:
Joy E Tomlinson, Raphael Wolfisberg, Ulrik Fahnøe, Himanshu Sharma, Randall W Renshaw, Louise Nielsen, Eiko Nishiuchi, Christina Holm, Edward Dubovi, Brad R Rosenberg, Bud C Tennant, Jens Bukh, Amit Kapoor, Thomas J Divers, Charles M Rice, Gerlinde R Van de Walle, Troels K H Scheel
Publikováno v:
PLoS Pathogens, Vol 16, Iss 7, p e1008677 (2020)
Pegiviruses frequently cause persistent infection (as defined by >6 months), but unlike most other Flaviviridae members, no apparent clinical disease. Human pegivirus (HPgV, previously GBV-C) is detectable in 1-4% of healthy individuals and another 5
Externí odkaz:
https://doaj.org/article/86b673d6cd5a45f290ac6aa03731e272
Autor:
Nikola Danev, Julia M. Poggi, Emilie A. Dewever, Arianna P. Bartlett, Leane Oliveira, Lucas Huntimer, Rebecca M. Harman, Gerlinde R. Van de Walle
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Background The secretome of primary bovine mammosphere-derived epithelial cells (MDECs) has been shown to exert antimicrobial, regenerative, and immunomodulatory properties in vitro, which warrants its study as a potential biologic treatment
Externí odkaz:
https://doaj.org/article/1b9971f359b94d968703be0abd4037c3
Autor:
Amy Fulton, Sarah T Peters, Gillian A Perkins, Keith W Jarosinski, Armando Damiani, Margaret Brosnahan, Elizabeth L Buckles, Nikolaus Osterrieder, Gerlinde R Van de Walle
Publikováno v:
PLoS ONE, Vol 4, Iss 1, p e4118 (2009)
BACKGROUND: Equine herpesvirus type 1 (EHV-1), a member of the Alphaherpesvirinae, is spread via nasal secretions and causes respiratory disease, neurological disorders and abortions. The virus is a significant equine pathogen, but current EHV-1 vacc
Externí odkaz:
https://doaj.org/article/b7a9ae256f7d4fcc877e47948290fb5c
The mammosphere-derived epithelial cell secretome modulates neutrophil functions in the bovine model
Autor:
Rebecca M. Harman, Anja Sipka, Kelly A. Oxford, Leane Oliveira, Lucas Huntimer, Daryl V. Nydam, Gerlinde R. Van de Walle
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundInnovative therapies against bacterial infections are needed. One approach is to focus on host-directed immunotherapy (HDT), with treatments that exploit natural processes of the host immune system. The goals of this type of therapy are to
Externí odkaz:
https://doaj.org/article/80f27f40edfe4144bf907385cf17ee7f
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-14 (2023)
Abstract Mammary cancer incidence varies greatly across species and underlying mechanisms remain elusive. We previously showed that mammosphere-derived epithelial cells from species with low mammary cancer incidence, such as horses, respond to carcin
Externí odkaz:
https://doaj.org/article/c0ee9a694a4f4a8b8a6eaf7318f4180b
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract The bovine mammary stem/progenitor cell secretome stimulates regeneration in vitro and contains proteins associated with antimicrobial defense. This has led to the exploration of the secretome as a biologic treatment for mastitis, a costly i
Externí odkaz:
https://doaj.org/article/ab2c29d22f6643e9a790049c1f3436a7
Publikováno v:
iScience, Vol 27, Iss 2, Pp 108886- (2024)
Summary: Mesenchymal stromal cells (MSCs) have the potential to be used as therapeutics, but their efficacy varies due to cellular heterogeneity, which is not fully understood. After characterizing donor-matched bovine MSC from adipose tissue (AT), b
Externí odkaz:
https://doaj.org/article/1506f6985bd64efb8546ab5dae65f0d2
Publikováno v:
Frontiers in Veterinary Science, Vol 10 (2023)
Ruminant livestock, including cattle, sheep, goat, and buffalo, are essential for global food security and serve valuable roles in sustainable agricultural systems. With the limited availability of embryonic stem cells (ESCs) from these species, rumi
Externí odkaz:
https://doaj.org/article/d14fb17419704de0ad5fd511d768c66d
Autor:
Joy Ellen Tomlinson, Mason Jager, Alyssa Struzyna, Melissa Laverack, Lisa Ann Fortier, Edward Dubovi, Lane D. Foil, Peter D. Burbelo, Thomas J. Divers, Gerlinde R. Van de Walle
Publikováno v:
Emerging Microbes and Infections, Vol 9, Iss 1, Pp 651-663 (2020)
ABSTRACTEquine parvovirus-hepatitis (EqPV-H) has recently been associated with cases of Theiler's disease, a form of fulminant hepatic necrosis in horses. To assess whether EqPV-H is the cause of Theiler's disease, we first demonstrated hepatotropism
Externí odkaz:
https://doaj.org/article/49e4f885795a4428b36d463bc85ff717
Autor:
James L. Miller, Matt Kanke, Gat Rauner, Kimaya M. Bakhle, Praveen Sethupathy, Gerlinde R. Van de Walle
Publikováno v:
Journal of Mammary Gland Biology and Neoplasia. 27:253-269