Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Gerlinde Obermoser"'
Autor:
Afroza Akter, Tasnuva Ahmed, Imam Tauheed, Marjahan Akhtar, Sadia Isfat Ara Rahman, Fatema Khaton, Faisal Ahmmed, Jannatul Ferdous, Mokibul Hassan Afrad, Zannat Kawser, Mohabbat Hossain, Rabeya Khondaker, Mohammad Abul Hasnat, Mostafa Aziz Sumon, Asif Rashed, Shuvro Ghosh, Stephen B Calderwood, Richelle C Charles, Edward T Ryan, Purvesh Khatri, Holden Terry Maecker, Gerlinde Obermoser, Bali Pulendran, John D Clemens, Sayera Banu, Tahmina Shirin, Regina C LaRocque, Jason B Harris, Taufiqur Rahman Bhuiyan, Fahima Chowdhury, Firdausi Qadri
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 16, Iss 1, p e0010102 (2022)
BackgroundCOVID-19 caused by SARS-CoV-2 ranges from asymptomatic to severe disease and can cause fatal and devastating outcome in many cases. In this study, we have compared the clinical, biochemical and immunological parameters across the different
Externí odkaz:
https://doaj.org/article/33ee005075964cca9eff11b1f61f11bc
Autor:
Natalie Stanley, Ina A. Stelzer, Amy S. Tsai, Ramin Fallahzadeh, Edward Ganio, Martin Becker, Thanaphong Phongpreecha, Huda Nassar, Sajjad Ghaemi, Ivana Maric, Anthony Culos, Alan L. Chang, Maria Xenochristou, Xiaoyuan Han, Camilo Espinosa, Kristen Rumer, Laura Peterson, Franck Verdonk, Dyani Gaudilliere, Eileen Tsai, Dorien Feyaerts, Jakob Einhaus, Kazuo Ando, Ronald J. Wong, Gerlinde Obermoser, Gary M. Shaw, David K. Stevenson, Martin S. Angst, Brice Gaudilliere, Nima Aghaeepour
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Single-cell technologies are increasingly prominent in clinical applications, but predictive modelling with such data in large cohorts has remained computationally challenging. We developed a new algorithm, ‘VoPo’, for predictive modelling and vi
Externí odkaz:
https://doaj.org/article/e63eb4be164c423694059f87cd18e59d
Autor:
Deborah L. Cross, Marije K. Verheul, Michael D. Leipold, Gerlinde Obermoser, Celina Jin, Elizabeth Jones, Joshua S. Starr, Irina Mohorianu, Christoph J. Blohmke, Holden T. Maecker, Giorgio Napolitani, Jennifer Hill, Andrew J. Pollard
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Vi-polysaccharide conjugate vaccines are efficacious against cases of typhoid fever; however, an absolute correlate of protection is not established. In this study, we investigated the leukocyte response to a Vi-tetanus toxoid conjugate vaccine (Vi-T
Externí odkaz:
https://doaj.org/article/18154f04f8854243816e5256d03d16db
Autor:
A. Karolina Palucka, Joyce O'Shaughnessy, Virginia Pascual, Jacques Banchereau, George J. Snipes, Kyp L. Oxley, Alma-Martina Cepika, Jennifer L. Smith, Cheng-Han Chung, Sookyoung Bae, Maren K. Levin, Elizabeth Lavecchio, Gerlinde Obermoser, Florentina Marches, Hannah M. Brookes, Derek Blankenship, Xuan Wang, Sandra Zurawski, Kyung In Kim, Jacob Turner, Joshy George, Romain Banchereau, Robyn R. Young, Jan Martinek, Kangling Xu, Te-Chia Wu
Cytokines screening from breast tumor tissue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1c07bf50424f86a306898391f903dc8
https://doi.org/10.1158/0008-5472.22419998.v1
https://doi.org/10.1158/0008-5472.22419998.v1
Autor:
A. Karolina Palucka, Joyce O'Shaughnessy, Virginia Pascual, Jacques Banchereau, George J. Snipes, Kyp L. Oxley, Alma-Martina Cepika, Jennifer L. Smith, Cheng-Han Chung, Sookyoung Bae, Maren K. Levin, Elizabeth Lavecchio, Gerlinde Obermoser, Florentina Marches, Hannah M. Brookes, Derek Blankenship, Xuan Wang, Sandra Zurawski, Kyung In Kim, Jacob Turner, Joshy George, Romain Banchereau, Robyn R. Young, Jan Martinek, Kangling Xu, Te-Chia Wu
Inflammation affects tumor immune surveillance and resistance to therapy. Here, we show that production of IL1β in primary breast cancer tumors is linked with advanced disease and originates from tumor-infiltrating CD11c+ myeloid cells. IL1β produc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::879d7de317c1fbaf2b7e2ef5329e3d05
https://doi.org/10.1158/0008-5472.c.6510527.v1
https://doi.org/10.1158/0008-5472.c.6510527.v1
Autor:
A. Karolina Palucka, Joyce O'Shaughnessy, Virginia Pascual, Jacques Banchereau, George J. Snipes, Kyp L. Oxley, Alma-Martina Cepika, Jennifer L. Smith, Cheng-Han Chung, Sookyoung Bae, Maren K. Levin, Elizabeth Lavecchio, Gerlinde Obermoser, Florentina Marches, Hannah M. Brookes, Derek Blankenship, Xuan Wang, Sandra Zurawski, Kyung In Kim, Jacob Turner, Joshy George, Romain Banchereau, Robyn R. Young, Jan Martinek, Kangling Xu, Te-Chia Wu
Figure S1. Cytokines screening from breast tumor tissue Figure S2. IL-1β induces TSLP production from breast cancer cells. Figure S3. IL-1β production in DCs is caspase-1 dependent. Figure S4. IL-1β production requires TAK1-dependent caspase-1 act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62d6cf027ece63c5df9f88f4332599ba
https://doi.org/10.1158/0008-5472.22420001.v1
https://doi.org/10.1158/0008-5472.22420001.v1
Autor:
Karolina Palucka, Randy A. Albrecht, Adolfo García-Sastre, Mark M. Davis, Gerlinde Obermoser, Jacques Banchereau, Dongxia Lin, Holden T. Maecker, Priyanka B. Subrahmanyam, Virginia Pascual, Tyson H. Holmes, Laura F. Su
Publikováno v:
ImmunoHorizons
The antiviral response to influenza virus is complex and multifaceted, involving many immune cell subsets. There is an urgent need to understand the role of CD4+ T cells, which orchestrate an effective antiviral response, to improve vaccine design st
Publikováno v:
Der Pathologe. 41:334-343
ZusammenfassungDer Lupus erythematodes (LE) ist eine Autoimmunerkrankung, bei der die Immuntoleranz gegenüber Nukleinsäuren verloren geht und es unter anderem durch ein enthemmtes Typ-I-Interferon-System zu einer chronischen Immunaktivierung kommt.
Autor:
Thomas J. Scriba, Erin W. Meermeier, Hennie Geldenhuys, Anele Gela, Elisa Nemes, Gerlinde Obermoser, W. Henry Boom, John L. Johnson, Munyaradzi Musvosvi, Christiaan Hopley, Asma Toefy, Willem A. Hanekom, Ashley Veldsman, Huang Huang, David M. Lewinsohn, Melissa Murphy, Sara Suliman, Nicole Bilek, Mark Hatherill
Publikováno v:
The Journal of Immunology Author Choice
Journal of immunology (Baltimore, Md. : 1950), vol 203, iss 11
Journal of immunology (Baltimore, Md. : 1950), vol 203, iss 11
Key Points MAIT cells comprise half the CD8 T cell IFN-γ response to BCG in blood. Frequencies of MAIT cells were not sustainably modulated by BCG vaccination. Innate cytokines mediate BCG-induced MAIT cell responses in whole blood.
Tuberculosi
Tuberculosi
Autor:
Munyaradzi, Musvosvi, Huang, Huang, Chunlin, Wang, Qiong, Xia, Virginie, Rozot, Akshaya, Krishnan, Peter, Acs, Abhilasha, Cheruku, Gerlinde, Obermoser, Alasdair, Leslie, Samuel M, Behar, Willem A, Hanekom, Nicole, Bilek, Michelle, Fisher, Stefan H E, Kaufmann, Gerhard, Walzl, Mark, Hatherill, Mark M, Davis, Thomas J, Scriba, Tran, Van
Publikováno v:
Nature medicine.
Antigen-specific, MHC-restricted αβ T cells are necessary for protective immunity against Mycobacterium tuberculosis, but the ability to broadly study these responses has been limited. In the present study, we used single-cell and bulk T cell recep