Zobrazeno 1 - 10
of 447
pro vyhledávání: '"Gerlag, P."'
Autor:
Ronald F van Vollenhoven, Danielle M Gerlag, Karen I Maijer, Sander W Tas, Niek de Vries, Paul P Tak, Robert B M Landewé, Lisa G M van Baarsen, Giulia Frazzei, Sophie H M Cramer
Publikováno v:
RMD Open, Vol 10, Iss 4 (2024)
Objectives Early treatment of individuals at risk of developing rheumatoid arthritis (RA-risk) in the preclinical phase has the potential to positively impact both patients and society by preventing disease onset and improving patients’ quality of
Externí odkaz:
https://doaj.org/article/1523f082a9b24d84afb908de20f35ef4
Akademický článek
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Autor:
Rebecca Birch, Gwenda Simons, Heidi Wähämaa, Catherine M. McGrath, Eva C. Johansson, Diana Skingle, Kerin Bayliss, Bella Starling, Danielle M. Gerlag, Christopher D. Buckley, Rebecca J. Stack, Karim Raza, Marie Falahee
Publikováno v:
Research Involvement and Engagement, Vol 6, Iss 1, Pp 1-14 (2020)
Plain English summary Patient and public involvement (PPI) improves the quality of health research and ensures that research is relevant to patients’ needs. Though PPI is increasingly evident in clinical and health services research, there are few
Externí odkaz:
https://doaj.org/article/46d46370641d49eabd5fc8eade3bc020
Autor:
Esther N.M. de Rooij, Friedo W. Dekker, Saskia Le Cessie, Ewout J. Hoorn, Johan W. de Fijter, Ellen K. Hoogeveen, J.A. Bijlsma, M. Boekhout, W.H. Boer, P.J.M. van der Boog, H.R. Büller, M. van Buren, F.Th. de Charro, C.J. Doorenbos, M.A. van den Dorpel, A. van Es, W.J. Fagel, G.W. Feith, C.W.H. de Fijter, L.A.M. Frenken, W. Grave, J.A.C.A. van Geelen, P.G.G. Gerlag, J.P.M.C. Gorgels, R.M. Huisman, K.J. Jager, K. Jie, W.A.H. Koning-Mulder, M.I. Koolen, T.K. Kremer Hovinga, A.T.J. Lavrijssen, A.J. Luik, J. van der Meulen, K.J. Parlevliet, M.H.M. Raasveld, F.M. van der Sande, M.J.M. Schonck, M.M.J. Schuurmans, C.E.H. Siegert, C.A. Stegeman, P. Stevens, J.G.P. Thijssen, R.M. Valentijn, G.H. Vastenburg, C.A. Verburgh, H.H. Vincent, P.F. Vos
Publikováno v:
Kidney Medicine, Vol 4, Iss 1, Pp 100379- (2022)
Rationale & Objective: Both hypo- and hyperkalemia can cause fatal cardiac arrhythmias. Although predialysis serum potassium level is a known modifiable risk factor for death in patients receiving hemodialysis, especially for hypokalemia, this risk m
Externí odkaz:
https://doaj.org/article/402dd7e99ace418eb94bfb351bfd4218
Autor:
Marius de Groot, Neel Patel, Roido Manavaki, Robert L. Janiczek, Mats Bergstrom, Andrew Östör, Danielle Gerlag, Alexandra Roberts, Martin J. Graves, Yakshitha Karkera, Disala Fernando, Prafull Mistry, Adam Walker, Nicolas Wisniacki, Tim D. Fryer, Pilar Jimenez-Royo
Publikováno v:
EJNMMI Research, Vol 9, Iss 1, Pp 1-11 (2019)
Abstract Purpose While the aetiology of rheumatoid arthritis (RA) remains unclear, many of the inflammatory components are well characterised. For diagnosis and therapy evaluation, in vivo insight into these processes would be valuable. Various imagi
Externí odkaz:
https://doaj.org/article/f25e31e523564759adfb8b73d012a28d
Autor:
Andrew Y. F. Li Yim, Enrico Ferrero, Klio Maratou, Huw D. Lewis, George Royal, David F. Tough, Chris Larminie, Marcel M. A. M. Mannens, Peter Henneman, Wouter J. de Jonge, Marleen G. H. van de Sande, Danielle M. Gerlag, Rab K. Prinjha, Paul P. Tak
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
In this study, we sought to characterize synovial tissue obtained from individuals with arthralgia and disease-specific auto-antibodies and patients with established rheumatoid arthritis (RA), by applying an integrative multi-omics approach where we
Externí odkaz:
https://doaj.org/article/b65fadd8bd9d4285968860c81c44f2e9
Autor:
Dornatien Chuo Anang, Tamara H. Ramwadhdoebe, Janine S. Hähnlein, Bo van Kuijk, Noortje Smits, Krijn P. van Lienden, Mario Maas, Daniëlle M. Gerlag, Paul P. Tak, Niek de Vries, Lisa G. M. van Baarsen
Publikováno v:
Cells, Vol 11, Iss 7, p 1104 (2022)
Follicular T helper cells (Tfh cells) provide key B-cell help and are essential in germinal center formation and (auto) antibody generation. To gain more insight into their role during the earliest phase of rheumatoid arthritis (RA), we analyzed thei
Externí odkaz:
https://doaj.org/article/e38b906e9461465c996a344d9fd2414a
Autor:
Janne W. Bolt, Arno W. van Kuijk, Marcel B. M. Teunissen, Dennis van der Coelen, Saïda Aarrass, Daniëlle M. Gerlag, Paul P. Tak, Marleen G. van de Sande, Maria C. Lebre, Lisa G. M. van Baarsen
Publikováno v:
Biomedicines, Vol 10, Iss 2, p 324 (2022)
Interleukin (IL)-17 and tumor necrosis factor-alpha (TNF)-α are key players in psoriatic arthritis (PsA) pathogenesis. While both cytokines can be therapeutically targeted with beneficial clinical outcome, it is unclear whether inhibiting one cytoki
Externí odkaz:
https://doaj.org/article/af3b332d97a341f89038d54ef84ada5f
Autor:
Janine S. Hähnlein, Reza Nadafi, Tineke de Jong, Tamara H. Ramwadhdoebe, Johanna F. Semmelink, Karen I. Maijer, IJsbrand A. Zijlstra, Mario Maas, Danielle M. Gerlag, Teunis B. H. Geijtenbeek, Paul P. Tak, Reina E. Mebius, Lisa G. M. van Baarsen
Publikováno v:
Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-12 (2018)
Abstract Background Systemic autoimmunity can be present years before clinical onset of rheumatoid arthritis (RA). Adaptive immunity is initiated in lymphoid tissue where lymph node stromal cells (LNSCs) regulate immune responses through their intima
Externí odkaz:
https://doaj.org/article/791ad70409a34ac39aabe61b93ef46c5
Autor:
Jennie H. M. Yang, Leena Khatri, Marius Mickunas, Evangelia Williams, Danijela Tatovic, Mohammad Alhadj Ali, Philippa Young, Penelope Moyle, Vishal Sahni, Ryan Wang, Rejbinder Kaur, Gillian M. Tannahill, Andrew R. Beaton, Danielle M. Gerlag, Caroline O. S. Savage, Antonella Napolitano Rosen, Frank Waldron-Lynch, Colin M. Dayan, Timothy I. M. Tree
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Background: Ultrasound guided sampling of human lymph node (LN) combined with advanced flow cytometry allows phenotypic analysis of multiple immune cell subsets. These may provide insights into immune processes and responses to immunotherapies not ap
Externí odkaz:
https://doaj.org/article/69d6c7577a7e4a29879bacbc563ce034