Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Geri Traver"'
Publikováno v:
Cancer letters
The ability of chemo-radiation therapy to control locally advanced stage III non-small cell lung cancer (NSCLC) is poor. While addition of consolidation immunotherapy has improved outcomes in subsets of patients there is still an urgent need for new
Autor:
Michael L. Freeman, Kelli L. Boyd, Daniel Dean, Rebecca A. Ihrie, Brent D. Cameron, Geri Traver, Joseph T. Roland, Asa A. Brockman, Levi Johnson
Publikováno v:
Stem Cells (Dayton, Ohio)
The ventricular–subventricular zone (V‐SVZ) of the mammalian brain is a site of adult neurogenesis. Within the V‐SVZ reside type B neural stem cells (NSCs) and type A neuroblasts. The V‐SVZ is also a primary site for very aggressive glioblast
Autor:
George X. Ding, David Gius, William Lawson, Konjeti R. Sekhar, Michael L. Freeman, Stacey Mont, Geri Traver
Publikováno v:
Free Radical Biology and Medicine. 112:578-586
The development of radiation-induced pulmonary fibrosis represents a critical clinical issue limiting delivery of therapeutic doses of radiation to non-small cell lung cancer. Identification of the cell types whose injury initiates a fibrotic respons
Publikováno v:
Clinical Cancer Research. 27:PR-003
NPM1 is a chaperone involved in base excision, translesion synthesis and homologous recombination (HR). In the presence of DNA DSBs pT199 NPM1 co-localizes with H2AX foci, a consequence of binding to K63-linked ubiquitinated histones that surround DS
Autor:
Konjeti R. Sekhar, Michael L. Freeman, Peter A. Crooks, Clayton A. Smith, Geri Traver, Stacey Mont
Publikováno v:
Oncotarget
// Clayton A. Smith 1, 2 , Stacey Mont 1 , Geri Traver 1 , Konjeti R. Sekhar 1 , Peter A. Crooks 3 , Michael L. Freeman 1 1 Department of Radiation Oncology, Vanderbilt University Medical Center, Nashville, TN 37232, USA 2 Current Address: Department
Publikováno v:
Cancer Research. 80:6164-6164
Nucleophosmin1 (NPM1) is rapidly recruited to sites of DNA double-strand breaks and is required for radiation-induced Rad51 foci formation. Inhibition of NPM1 or Rad51 is a radiosensitizing event. YTR107 is a small molecule, identified in a forward c
Autor:
Michael L. Freeman, Brent D. Cameron, Geri Traver, Kelli L. Boyd, Jialiang Wang, Rebecca A. Ihrie, Joseph T. Roland, Daniel Dean, Levi Johnson
Publikováno v:
Cancer Research. 79:3934-3934
The subventricular zone (SVZ) is the largest source of neural stem cells (NSCs) in the adult brain. Emerging research indicates that NSCs within the SVZ may be cells of origin for WHO grade IV astrocytoma (glioblastoma, GBM)1. GBM consists of multipl
Autor:
Michael L. Freeman, M. Fahhoum, Konjeti R. Sekhar, Jian Wang, L. Johnson, Geri Traver, D. Dean, Brent D. Cameron
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 102:e154
Autor:
Maxwell Ofori, Konjeti R. Sekhar, Michael L. Freeman, Peter A. Crooks, Geri Traver, Narsimha R. Renthala
Publikováno v:
Cancer Research. 78:3189-3189
Ewing sarcoma is a rare cancer found in children and young adults. Long term survival rates are approximately 70% for patients who present without clinically overt metastases. However, 5 year survival is less than 20% for patients with recurrent tumo
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 96:S78