Zobrazeno 1 - 10
of 156
pro vyhledávání: '"Gerhard Wunderlich"'
Autor:
Luisa Fernanda Ortega Sepulveda, Gabriela Mendes de Oliveira, Elaine Hellen Nunes Chagas, Nele Wild, Franciarli Silva da Paz, Carsten Wrenger, Gerhard Wunderlich
Publikováno v:
Future Pharmacology, Vol 3, Iss 4, Pp 846-861 (2023)
The complex life cycle of the malaria parasite Plasmodium requires the parasite to adequately adapt to different conditions. For this reason, Plasmodium strictly controls its gene expression, and given its evolutionary distance from the human host, t
Externí odkaz:
https://doaj.org/article/f6939caaf97c43e19f0a5075a1d12393
Autor:
Meseret W. Kassa, Wina Hasang, André Barateiro, Timon Damelang, Jessica Brewster, Jamille G. Dombrowski, Rhea J. Longley, Amy W. Chung, Gerhard Wunderlich, Ivo Mueller, Elizabeth H. Aitken, Claudio R. F. Marinho, Stephen J. Rogerson
Publikováno v:
Malaria Journal, Vol 21, Iss 1, Pp 1-14 (2022)
Abstract Background Pregnant women have increased susceptibility to Plasmodium falciparum malaria and acquire protective antibodies over successive pregnancies. Most studies that investigated malaria antibody responses in pregnant women are from high
Externí odkaz:
https://doaj.org/article/145769ab7c974e88849fdad194847212
Publikováno v:
Malaria Journal, Vol 20, Iss 1, Pp 1-7 (2021)
Abstract Background Molecular and genetic studies of blood-stage Plasmodium falciparum parasites require limiting dilution cloning and prolonged cultivation in microplates. The entire process is laborious and subject to errors due to inaccurate dilut
Externí odkaz:
https://doaj.org/article/50c1c3a57b3643f39947d1fd07117f16
Autor:
Wesley L. Fotoran, Jamile Ramos da Silva, Christiane Glitz, Luís Carlos de Souza Ferreira, Gerhard Wunderlich
Publikováno v:
Pharmaceutics, Vol 15, Iss 4, p 1223 (2023)
Background: Nucleic acid-based vaccines have been studied for the past four decades, but the approval of the first messenger RNA (mRNA) vaccines during the COVID-19 pandemic opened renewed perspectives for the development of similar vaccines against
Externí odkaz:
https://doaj.org/article/ee619de033b04cdca6ca0fd1c88d1dff
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Externí odkaz:
https://doaj.org/article/a55dd1ec78c340d8b06006c40987f1dd
Autor:
Eliana F. G. Cubillos, Isadora Oliveira Prata, Wesley Luzetti Fotoran, Lisa Ranford-Cartwright, Gerhard Wunderlich
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
The human malaria parasite Plasmodium falciparum expresses variant PfEMP1 proteins on the infected erythrocyte, which function as ligands for endothelial receptors in capillary vessels, leading to erythrocyte sequestration and severe malaria. The fac
Externí odkaz:
https://doaj.org/article/39f4b6f9987f4779b09b5064a0dd29bc
Autor:
Jamille Gregório Dombrowski, André Barateiro, Erika Paula Machado Peixoto, André Boler Cláudio da Silva Barros, Rodrigo Medeiros de Souza, Taane Gregory Clark, Susana Campino, Carsten Wrenger, Gerhard Wunderlich, Giuseppe Palmisano, Sabrina Epiphanio, Lígia Antunes Gonçalves, Claudio Romero Farias Marinho
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 4, p e0009390 (2021)
BackgroundMalaria in Brazil represents one of the highest percentages of Latin America cases, where approximately 84% of infections are attributed to Plasmodium (P.) vivax. Despite the high incidence, many aspects of gestational malaria resulting fro
Externí odkaz:
https://doaj.org/article/56dcc7cdad8346598cc17f1449dcbef0
Publikováno v:
Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 26 (2020)
Abstract Background: Liposomes are highly useful carriers for delivering drugs or antigens. The association of glycosylphosphatidylinositol (GPI)-anchored proteins to liposomes potentially enhances the immunogenic effect of vaccine antigens by increa
Externí odkaz:
https://doaj.org/article/8cc7df5e18554ca694313ca9b4c16326
Autor:
Wesley L. Fotoran, Rachele Santangelo, Beatriz N.M. de Miranda, Darrell J. Irvine, Gerhard Wunderlich
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 7, Iss C, Pp 1-10 (2017)
The delivery of antigens as DNA vaccines is an efficient alternative to induce immune responses against antigens, which are difficult to produce in recombinant form. However, the delivery of naked DNA is ineffective or relies on sophisticated ballist
Externí odkaz:
https://doaj.org/article/3edd3eab100346dcb95232f5cf63e7d5
Autor:
Eliana Ferreira Monteiro, Carmen Fernandez-Becerra, Izilda Curado, Gerhard Wunderlich, Meire Ioshie Hiyane, Karin Kirchgatter
Publikováno v:
Pathogens, Vol 10, Iss 9, p 1138 (2021)
Plasmodium malariae has a wide geographic distribution, but mainly at very low parasitemias and in co-infections, leading to an underestimated prevalence of this species. Studies for the detection of antibodies against Plasmodium recombinant proteins
Externí odkaz:
https://doaj.org/article/3148625c865046b3b302038978f84f1b