Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Gerhard Stadlmayr"'
Autor:
Stefan Vogt, Madhusudhan Reddy Bobbili, Gerhard Stadlmayr, Katharina Stadlbauer, Jørgen Kjems, Florian Rüker, Johannes Grillari, Gordana Wozniak‐Knopp
Publikováno v:
Journal of Extracellular Vesicles, Vol 10, Iss 11, Pp n/a-n/a (2021)
Abstract The research of extracellular vesicles (EVs) has boomed in the last decade, with the promise of them functioning as target‐directed drug delivery vehicles, able to modulate proliferation, migration, differentiation, and other properties of
Externí odkaz:
https://doaj.org/article/6bb7e1c4aa194071801a85a4ec26f2e8
Autor:
Filippo Benedetti, Florian Stracke, Gerhard Stadlmayr, Katharina Stadlbauer, Florian Rüker, Gordana Wozniak-Knopp
Publikováno v:
Biochemistry and Biophysics Reports, Vol 26, Iss , Pp 100959- (2021)
Monoclonal antibodies can acquire the property of engagement of a second antigen via fusion methods or modification of their CDR loops, but also by modification of their constant domains, such as in the mAb2 format where a set of mutated amino acid r
Externí odkaz:
https://doaj.org/article/c43f517524754880b430364cfea6437b
Autor:
Miriam Klausberger, Mark Duerkop, Helmuth Haslacher, Gordana Wozniak-Knopp, Monika Cserjan-Puschmann, Thomas Perkmann, Nico Lingg, Patricia Pereira Aguilar, Elisabeth Laurent, Jelle De Vos, Manuela Hofner, Barbara Holzer, Maria Stadler, Gabriele Manhart, Klemens Vierlinger, Margot Egger, Lisa Milchram, Elisabeth Gludovacz, Nicolas Marx, Christoph Köppl, Christopher Tauer, Jürgen Beck, Daniel Maresch, Clemens Grünwald-Gruber, Florian Strobl, Peter Satzer, Gerhard Stadlmayr, Ulrike Vavra, Jasmin Huber, Markus Wahrmann, Farsad Eskandary, Marie-Kathrin Breyer, Daniela Sieghart, Peter Quehenberger, Gerda Leitner, Robert Strassl, Alexander E. Egger, Christian Irsara, Andrea Griesmacher, Gregor Hoermann, Günter Weiss, Rosa Bellmann-Weiler, Judith Loeffler-Ragg, Nicole Borth, Richard Strasser, Alois Jungbauer, Rainer Hahn, Jürgen Mairhofer, Boris Hartmann, Nikolaus B. Binder, Gerald Striedner, Lukas Mach, Andreas Weinhäusel, Benjamin Dieplinger, Florian Grebien, Wilhelm Gerner, Christoph J. Binder, Reingard Grabherr
Publikováno v:
EBioMedicine, Vol 67, Iss , Pp 103348- (2021)
Background: Antibody tests are essential tools to investigate humoral immunity following SARS-CoV-2 infection or vaccination. While first-generation antibody tests have primarily provided qualitative results, accurate seroprevalence studies and track
Externí odkaz:
https://doaj.org/article/ba1f6bc358354ac0a5baccc4ebc09bec
Autor:
Aleksandra Rodak, Gerhard Stadlmayr, Katharina Stadlbauer, Dominic Lichtscheidl, Madhusudhan Reddy Bobbili, Florian Rüker, Gordana Wozniak-Knopp
Publikováno v:
Biomedicines, Vol 9, Iss 11, p 1568 (2021)
The increased incidence of allergies and asthma has sparked interest in IgE, the central player in the allergic response. Interaction with its high-affinity receptor FcεRI leads to sensitization and allergen presentation, extracellular membrane-prox
Externí odkaz:
https://doaj.org/article/d5a2f8f936e9455eb7b76ffab63946c1
Autor:
Filippo Benedetti, Katharina Stadlbauer, Gerhard Stadlmayr, Florian Rüker, Gordana Wozniak-Knopp
Publikováno v:
Life, Vol 11, Iss 11, p 1157 (2021)
The overexpression of tyrosine kinase HER2 in numerous cancers, connected with fierce signaling and uncontrolled proliferation, makes it a suitable target for immunotherapy. The acquisition of resistance to currently used compounds and the multiplici
Externí odkaz:
https://doaj.org/article/f42e6e0c6abc414a8056859947759502
Autor:
Gordana Wozniak-Knopp, Gerhard Stadlmayr, Jan Walther Perthold, Katharina Stadlbauer, Mathias Gotsmy, Stefan Becker, Florian Rüker
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0195442 (2018)
We have designed a complete antibody-like construct where the CH1 and Cκ domains are exchanged for a pair of the CH3 domains and efficient pairing of the heavy and light variable domain is achieved using "Knobs-into-Holes" strategy. This construct,
Externí odkaz:
https://doaj.org/article/6fd29778184a4a0396484ba2c6136214
Autor:
Stefan Vogt, Gerhard Stadlmayr, Katharina Stadlbauer, Flávio Sádio, Peter Andorfer, Johannes Grillari, Florian Rüker, Gordana Wozniak-Knopp
Publikováno v:
Pharmaceutics, Vol 10, Iss 3, p 138 (2018)
Tetraspan proteins are significantly enriched in the membranes of exosomal vesicles (EVs) and their extracellular domains are attractive targets for engineering towards specific antigen recognition units. To enhance the tolerance of a tetraspanin fol
Externí odkaz:
https://doaj.org/article/87f2b8d2374e4b10bd2d37e083e8ef0f
Autor:
Veronica Natale, Gerhard Stadlmayr, Filippo Benedetti, Katharina Stadlbauer, Florian Rüker, Gordana Wozniak-Knopp
Publikováno v:
Biological Chemistry. 403:509-523
Bispecific antibodies and antibody fragments are therapeutics of growing importance. They are clinically applied for effector cell engagement, enhanced targeting selectivity, addressing of multiple cellular pathways and active transfer of certain act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2169ac755ec1147e9b4af3c0ddc1bf7e
https://doi.org/10.1515/hsz-2021-0376
https://doi.org/10.1515/hsz-2021-0376
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ca8aa6046b950baeca0dfadff87bf3f
https://doi.org/10.2139/ssrn.4358880
https://doi.org/10.2139/ssrn.4358880
Publikováno v:
BIOspektrum. 27:495-499
Nearly seventy years have passed since the first attempts to fuse the antibodies, „magic bullets“ with exquisite target specificity, into multispecific agents that can connect a targeted cell with an effector immune cell. Such efforts have trigge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f74964416aabef0550eba71906f3a6f5
https://doi.org/10.1007/s12268-021-1618-0
https://doi.org/10.1007/s12268-021-1618-0