Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Gerhard Rubner"'
Autor:
Sandra Meieranz, Maria Stefanopoulou, Kerstin Bensdorf, Dominic Kubutat, Ronald Gust, William S. Sheldrick, Gerhard Rubner
Publikováno v:
Angewandte Chemie. 127:2876-2879
Autor:
Gerhard Rubner, Kerstin Bensdorf, Brigitte Kircher, Ronald Gust, Anja Wellner, Silke Bergemann, Ingo Ott
Publikováno v:
Journal of Medicinal Chemistry. 53:6889-6898
[(μ(4)-η(2))-(Prop-2-ynyl)-2-acetoxybenzoate]dicobalthexacarbonyl (Co-ASS), a derivative of aspirin (ASS), demonstrated high growth-inhibitory potential against various tumor cells with interference in the arachidonic acid cascade as probable mode
Autor:
William S. Sheldrick, Dominic Kubutat, Kerstin Bensdorf, Gerhard Rubner, Maria Stefanopoulou, Ronald Gust, Sandra Meieranz
Publikováno v:
Angewandte Chemie (International ed. in English). 54(9)
With the aim to design new biologically active bioinorganic drugs of aspirin, whose mode of action is based on the inhibition of the cyclooxygenase(COX) enzymes, derivatives of Zeise’s salt were synthesized in this structure–activity relationship
Autor:
Jinpei Zhou, Gerhard Rubner, Yanchun Zhang, Haoran Liu, Kerstin Bensdorf, Hai Qian, Can-Cheng Guo, Huibin Zhang, Ronald Gust, Wenlong Huang, Yubin Wang, Wukun Liu, Anja Wellner
Publikováno v:
European journal of medicinal chemistry. 46(3)
A series of C5-substituted licofelone ([2,2-dimethyl-6-(4-chlorophenyl)-7-phenyl-2,3-dihydro-1H-pyrrolizin-5-yl]acetic acid) derivatives were developed by a parallel synthesis approach and investigated for cytotoxicity against MCF-7 and MDA-MB-231 ce
Publikováno v:
European journal of medicinal chemistry. 45(11)
[(Prop-2-ynyl)-2-acetoxybenzoate]dicobalthexacarbonyl (Co-ASS), a derivative of the nonsteroidal anti-inflammatory drug aspirin(®) (ASS), demonstrated high cytotoxic potential against various tumor cells. The [acetylene]Co(2)(CO)(6) cluster strongly