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Publikováno v:
Angewandte Chemie. 107:195-197
Autor:
Jurij Stekar, Jürgen Engel, Rainer Voegeli, Gerhard Nößner, Wolfgang Schumacher, H. Rainer Maurer, Peter Hilgard, Bernhard Kutscher
Publikováno v:
Cancer chemotherapy and pharmacology. 32(6)
Octadecyl-[2-(N-methylpiperidinio)ethyl]-phosphate (OMPEP, D-20133), a heterocyclic analogue of hexadecylphosphocholine (MIL), has been synthesized in an attempt to increase the therapeutic range of the parent compound. The antineoplastic activity of