Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Gerhard Moser"'
Autor:
Marion Patxot, Daniel Trejo Banos, Athanasios Kousathanas, Etienne J. Orliac, Sven E. Ojavee, Gerhard Moser, Alexander Holloway, Julia Sidorenko, Zoltan Kutalik, Reedik Mägi, Peter M. Visscher, Lars Rönnegård, Matthew R. Robinson
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Improving inference in large-scale genetic data linked to electronic medical record data requires the development of novel computationally efficient regression methods. Here, the authors develop a Bayesian approach for association analyses to improve
Externí odkaz:
https://doaj.org/article/d0005592df464e3ea0bdfbf2ebf8a4d7
Autor:
Luke R. Lloyd-Jones, Jian Zeng, Julia Sidorenko, Loïc Yengo, Gerhard Moser, Kathryn E. Kemper, Huanwei Wang, Zhili Zheng, Reedik Magi, Tõnu Esko, Andres Metspalu, Naomi R. Wray, Michael E. Goddard, Jian Yang, Peter M. Visscher
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Various approaches are being used for polygenic prediction including Bayesian multiple regression methods that require access to individual-level genotype data. Here, the authors extend BayesR to utilise GWAS summary statistics (SBayesR) and show tha
Externí odkaz:
https://doaj.org/article/08ca063725f844dd8f1661fc58a72c97
Autor:
Guo-Bo Chen, Sang Hong Lee, Grant W. Montgomery, Naomi R. Wray, Peter M. Visscher, Richard B. Gearry, Ian C. Lawrance, Jane M. Andrews, Peter Bampton, Gillian Mahy, Sally Bell, Alissa Walsh, Susan Connor, Miles Sparrow, Lisa M. Bowdler, Lisa A. Simms, Krupa Krishnaprasad, the International IBD Genetics Consortium, Graham L. Radford-Smith, Gerhard Moser
Publikováno v:
BMC Medical Genetics, Vol 18, Iss 1, Pp 1-11 (2017)
Abstract Background Predicting risk of disease from genotypes is being increasingly proposed for a variety of diagnostic and prognostic purposes. Genome-wide association studies (GWAS) have identified a large number of genome-wide significant suscept
Externí odkaz:
https://doaj.org/article/7e80f872b9fa4900b531fd08ac729c24
Autor:
Teresa Magnes, Thomas Melchardt, Lukas Weiss, Christof Mittermair, Daniel Neureiter, Eckhard Klieser, Simon Gampenrieder, Gerhard Moser, Alexander Gaggl, Richard Greil, Alexander Egle
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0180995 (2017)
Despite modern treatment approaches, survival of patients with recurrent or metastatic squamous cell carcinoma of the head and neck (SCCHN) remains low and it is difficult to identify patients who derive optimal benefit from treatment. We therefore a
Externí odkaz:
https://doaj.org/article/6851cdc049dc49efac1a5f182ed27845
Publikováno v:
Cellular Physiology and Biochemistry, Vol 32, Iss 1, Pp 166-172 (2013)
Background: Sensorineural hearing loss (SNHL) in newborns is estimated with an incidence around 1:10,000 per year and is divided into syndromic and non-syndromic forms. In case of present retrocochlear function‚ cochlear implantation allows speech
Externí odkaz:
https://doaj.org/article/fc3956ff8f5a454881e832fb6d133978
Publikováno v:
PLoS Genetics, Vol 11, Iss 4, p e1004969 (2015)
Gene discovery, estimation of heritability captured by SNP arrays, inference on genetic architecture and prediction analyses of complex traits are usually performed using different statistical models and methods, leading to inefficiency and loss of p
Externí odkaz:
https://doaj.org/article/3074812b8139401f9cd28a7177b5827b
Autor:
Lukas D. Landegger, Clemens Honeder, Valerie Dahm, Christoph Arnoldner, Dominik Riss, Christian Matula, Gerhard Moser, Alice B. Auinger
Publikováno v:
Otology & Neurotology. 41:1266-1273
OBJECTIVE The aim of the study was to evaluate the predictive value regarding postoperative hearing benefit of electrically evoked auditory brainstem response audiometry in sporadic vestibular schwannoma patients undergoing simultaneous tumor resecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d9173b19593ab70c3cd24d9edcc2ba0
https://doi.org/10.1097/mao.0000000000002747
https://doi.org/10.1097/mao.0000000000002747
Autor:
G. Fastner, M. Kopp, Gerhard Moser, Christian Brandtner, Sebastian Roesch, Alexander Gaggl, Johannes Hachleitner
Publikováno v:
International Journal of Oral and Maxillofacial Surgery. 48:468-474
The purpose of this study was to describe a newly developed procedure for temporary mandibulotomy and subsequent osteosynthesis. Clinical outcomes were evaluated, including complications and the impact on postoperative treatment, particularly postope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66b0956de9f28313d5d7c3d69fea498b
https://doi.org/10.1016/j.ijom.2018.11.007
https://doi.org/10.1016/j.ijom.2018.11.007
Autor:
Lars Rönnegård, Athanasios Kousathanas, Gerhard Moser, Etienne J. Orliac, Alexander Holloway, Julia Sidorenko, Marion Patxot, Daniel Trejo Banos, Matthew R. Robinson, Peter M. Visscher, Sven Erik Ojavee, Reedik Mägi, Zoltán Kutalik
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
We develop a Bayesian model (BayesRR-RC) that provides robust SNP-heritability estimation, an alternative to marker discovery, and accurate genomic prediction, taking 22 seconds per iteration to estimate 8.4 million SNP-effects and 78 SNP-heritabilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80a6c14b16a6e0c7d3fb308f3634b6c5
http://urn.kb.se/resolve?urn=urn:nbn:se:du-39016
http://urn.kb.se/resolve?urn=urn:nbn:se:du-39016
Autor:
Gerhard Moser
In einfachen Worten erzählt der Protagonist aus seinem Leben. Nach einer glücklichen Kindheit folgt eine etwas kompliziertere Jugend, in welcher er sich fragt, warum er sich plötzlich in einen Jungen verliebt. Die Jahre bei den Jesus People und in