Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Gerhard Mihm"'
Autor:
Michael Goodfellow, Carsten H. Puder, Christina Bruntner, Alan C. Ward, Olivier Potterat, Alan T. Bull, Hans-Peter Fiedler, Gerhard Mihm
Publikováno v:
Antonie van Leeuwenhoek. 87:37-42
A set of 600 actinomycetes strains which were isolated from marine sediments from various sites in the Pacific and Atlantic Oceans were screened for the production of bioactive secondary metabolites. Marine streptomycete strains were found to be prod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::216271e73390855b6188a19558c9a91b
https://doi.org/10.1007/s10482-004-6538-8
https://doi.org/10.1007/s10482-004-6538-8
Autor:
Norbert Hauel, Wolfgang Wienen, Jacobus C. A. Van Meel, Berthold Narr, Kai M. Hasselbach, Uwe Ries, Helmut Wittneben, Gerhard Mihm, Michael Entzeroth
Publikováno v:
Journal of Medicinal Chemistry. 36:4040-4051
Starting from the recently reported nonpeptidic angiotensin II (AII) receptor antagonists DuP753 (1) and Exp 7711 (2), we have designed and investigated novel substituted benzimidazoles. Systemic variation of several substituents at the benzimidazole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6ead8ec4cc65146e06e80b97c72a90a
https://doi.org/10.1021/jm00077a007
https://doi.org/10.1021/jm00077a007
Autor:
Henri Doods, Ziegler Harald, Wolfhard Engel, Giovanni Battista Schiavi, Klaus Rudolf, Gerhard Mihm, Michael Entzeroth, Wolfgang Eberlein
Publikováno v:
European Journal of Pharmacology. 242:23-30
The present study was designed to characterize the receptor selectivity profile of the novel muscarinic M2 receptor antagonist BIBN 99 (5,11-dihydro-8-chloro-11-[[4-[3-[(2,2-dimethyl-1- oxopentyl)ethylamino]propyl]-1-piperidinyl]acetyl]-6H- pyrido[2,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::273a1c6f25ccbfb3713eaefef48aee43
https://doi.org/10.1016/0014-2999(93)90005-3
https://doi.org/10.1016/0014-2999(93)90005-3
Autor:
Hans-Peter Fiedler, Christina Bruntner, Walter Bolek, Tatiana Binder, Gerhard Mihm, Wasu Pathom-aree, Stefan Hörer, Angela Schmid, Carsten H. Puder, Michael Goodfellow, Olivier Potterat, Alan T. Bull, Klaus Wagner
Publikováno v:
The Journal of antibiotics. 58(5)
A new angucyclinone antibiotic, frigocyclinone, was isolated from Streptomyces griseus strain NTK 97, consisting of a tetrangomycin moiety attached through a C-glycosidic linkage with the aminodeoxysugar ossamine. Frigocyclinone showed antibacterial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::936b3991b5380a7cf745a63099e298ae
https://pubmed.ncbi.nlm.nih.gov/16060387
https://pubmed.ncbi.nlm.nih.gov/16060387
Autor:
Herbert Nar, Uwe Ries, Wolfgang Wienen, Henning Priepke, Sandra Handschuh, Gerhard Mihm, Jean Marie Stassen, Norbert Hauel
Publikováno v:
Bioorganicmedicinal chemistry letters. 13(14)
Quinoxalinone derivatives as prototypes of dual thrombin and factor Xa inhibitors have been discovered. Nanomolar inhibition of both coagulation enzymes resulted in very potent antithrombotic activity in vitro.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7307e01ec4e3529e8580b1a73516360
https://pubmed.ncbi.nlm.nih.gov/12824021
https://pubmed.ncbi.nlm.nih.gov/12824021
Publikováno v:
Angewandte Chemie. 94:864-865
Das vollstandige Manuskript dieser Zuschrift erscheint in: Angew. Chem. Suppl. 1982, 1785. DOI: 10.1002/ange.198217850
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::721680330cf5bd4cf776d59bfbb91e21
https://doi.org/10.1002/ange.19820941110
https://doi.org/10.1002/ange.19820941110
Autor:
Hans-Peter Fiedler, Christina Bruntner, Alan T. Bull, Alan C. Ward, Michael Goodfellow, Olivier Potterat, Carsten Puder, Gerhard Mihm
Publikováno v:
Antonie van Leeuwenhoek; Jan2005, Vol. 87 Issue 1, p37-42, 6p
Publikováno v:
Chemische Berichte. 117:2337-2350
Durch Kurzzeitpyrolyse der drei Silacyclohexadien-Derivate 5k, 5m und 7b last sich Silabenzol (1) erzeugen und in einer Argonmatrix bei 10 K isolieren. 1 zeichnet sich durch charakteristische IR- und UV-Spektren aus. Mittels photochemischer Anregung
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa868f2608975265472f4bc16369cdfd
https://doi.org/10.1002/cber.19841170707
https://doi.org/10.1002/cber.19841170707
Publikováno v:
Chemische Berichte. 117:2369-2381
Die Silaolefine 1 und dazu isomeren Methylsilylene 2 sind getrennt existenzfahige Spezies, lassen sich in einer Argonmatrix aber uber eine photochemisch induzierte 1,2-H-Wanderung leicht ineinander umwandeln. Bei thermischer Anregung in der Gasphase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d740c83b42379623f676a8cf1b4cdd0
https://doi.org/10.1002/cber.19841170709
https://doi.org/10.1002/cber.19841170709
Publikováno v:
Chemische Berichte. 117:2351-2368
Die Kombination von Vakuumblitzpyrolyse und Matrixisolierung gestattet es, Silaethen (1a) und seine einfach substituierten Derivate 1b – f ausgehend von den Silabicyclo[2.2.2]octadien-Vorlaufern 9a – f zu gewinnen. Die Silaolefine 1a – f sind i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee542ff754b95f540ad3969396b6bc42
https://doi.org/10.1002/cber.19841170708
https://doi.org/10.1002/cber.19841170708