Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Gerhard Ledinski"'
Autor:
Christine Rossmann, Cornelia Ranz, Gerd Kager, Gerhard Ledinski, Martin Koestenberger, Willibald Wonisch, Thomas Wagner, Sebastian P. Schwaminger, Bruno Di Geronimo, Andelko Hrzenjak, Seth Hallstöm, Gilbert Reibnegger, Gerhard Cvirn, Margret Paar
Publikováno v:
Pharmaceutics, Vol 15, Iss 8, p 2111 (2023)
Metformin is the most commonly prescribed glucose-lowering drug for the treatment of type 2 diabetes. The aim of this study was to investigate whether metformin is capable of impeding the oxidation of LDL, a crucial step in the development of endothe
Externí odkaz:
https://doaj.org/article/9bbf4f263d38442cb03d53efcf102673
Autor:
Christine Rossmann, Christoph Nusshold, Margret Paar, Gerhard Ledinski, Erwin Tafeit, Martin Koestenberger, Eva Maria Bernhart, Wolfgang Sattler, Gerhard Cvirn, Seth Hallström
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0191477 (2018)
Ethyl pyruvate (EP) exerts anti-inflammatory and anti-oxidative properties. The aim of our study was to investigate whether EP is capable of inhibiting the oxidation of LDL, a crucial step in atherogenesis. Additionally, we examined whether EP attenu
Externí odkaz:
https://doaj.org/article/fd4dc724112448d382148d5398527d18
Autor:
Gerd Hörl, Harald Froehlich, Ulrika Ferstl, Gerhard Ledinski, Josepha Binder, Gerhard Cvirn, Tatjana Stojakovic, Michael Trauner, Christoph Koidl, Erwin Tafeit, Karin Amrein, Hubert Scharnagl, Günther Jürgens, Seth Hallström
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0148210 (2016)
We investigated a polyethylene glycol non-precipitable low-density lipoprotein (LDL) subfraction targeted by IgG and the influence of statin therapy on plasma levels of these small LDL-IgG-immune complexes (LDL-IgG-IC). LDL-subfractions were isolated
Externí odkaz:
https://doaj.org/article/4e39da54b22f4e59ac7aff24a59deb8e
Autor:
Chiara Turrina, Anna Klassen, Davide Milani, Diana M. Rojas-González, Gerhard Ledinski, Doris Auer, Barbara Sartori, Gerhard Cvirn, Petra Mela, Sonja Berensmeier, Sebastian P. Schwaminger
Iron oxide nanoparticles (IONs) are of great interest in nanomedicine for imaging, drug delivery, or for hyperthermia treatment. Although many research groups have focused on the synthesis and application of IONs in nanomedicine, little is known abou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30ecb1f25826a39a693549d588673e6c
https://doi.org/10.26434/chemrxiv-2023-wx78h
https://doi.org/10.26434/chemrxiv-2023-wx78h
Autor:
Chiara Turrina, Anna Klassen, Davide Milani, Diana M. Rojas-González, Gerhard Ledinski, Doris Auer, Barbara Sartori, Gerhard Cvirn, Petra Mela, Sonja Berensmeier, Sebastian P. Schwaminger
Publikováno v:
Heliyon. 9:e16487
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3fe483510f56375ddf6e0c41b589d41e
https://doi.org/10.1016/j.heliyon.2023.e16487
https://doi.org/10.1016/j.heliyon.2023.e16487
Autor:
Irene, Schilcher, Gerhard, Ledinski, Snježana, Radulović, Seth, Hallström, Thomas, Eichmann, Tobias, Madl, Fangrong, Zhang, Gerd, Leitinger, Dagmar, Kolb-Lenz, Barbara, Darnhofer, Ruth, Birner-Gruenberger, Christian, Wadsack, Dagmar, Kratky, Gunther, Marsche, Saša, Frank, Gerhard, Cvirn
Publikováno v:
Biochimica et biophysica acta. Molecular and cell biology of lipids
Endothelial lipase (EL) is a strong determinant of structural and functional properties of high-density lipoprotein (HDL). We examined whether the antioxidative capacity of HDL is affected by EL. EL-modified HDL (EL-HDL) and control EV-HDL were gener
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::717f22209046fc956de0af784d329802
https://pubmed.ncbi.nlm.nih.gov/31220617
https://pubmed.ncbi.nlm.nih.gov/31220617
Autor:
Gerhard Cvirn, Axel Schlagenhauf, James Elvis Waha, Martin Koestenberger, Gerhard Ledinski, Bettina Leschnik, Nandu Goswami, Helmut Hinghofer-Szalkay, Erwin Tafeit
Publikováno v:
European Journal of Clinical Investigation. 45:63-69
Background Although there is no direct evidence, it is generally believed that bed rest shifts the haemostatic system towards hypercoagulability; thus, immobilized patients are commonly treated with anticoagulants. We therefore aimed to investigate w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47162b845dc0891335904fef1ecea316
https://doi.org/10.1111/eci.12383
https://doi.org/10.1111/eci.12383
Autor:
Guenther Juergens, Gerhard Cvirn, Thomas Gary, Martin Koestenberger, Gerhard Ledinski, Gerd Hoerl, Michael Thalhammer, Gerd Kager
Publikováno v:
Chemistry and Physics of Lipids. 184:38-41
Plaque formation is confined to the arterial trunk. We assumed that due to the higher aeration of arterial compared to venous blood, higher levels of the atherogenic agent oxidized LDL might be present in arteries, contributing to plaque formation. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bba558caf64b162c8155e6aac9d50d53
https://doi.org/10.1016/j.chemphyslip.2014.09.004
https://doi.org/10.1016/j.chemphyslip.2014.09.004
Autor:
Gernot Bruchelt, Gerhard Ledinski, Günther Jürgens, Claudia E. Gerber, Dietrich Niethammer, Joachim Greilberger
Publikováno v:
Redox Report. 7:111-119
The modification of low-density lipoprotein (LDL) by normal, myeloperoxidase (MPO)-deficient and NADPH oxidase-deficient granulocytes was investigated using the monoclonal antibody (mAb) OB/04, which was originally generated against copper-oxidized L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe87a131930dfabdb490469bcd4c784d
https://doi.org/10.1179/135100002125000343
https://doi.org/10.1179/135100002125000343
Autor:
Gunther Marsche, Saša Frank, Tobias Madl, Seth Hallström, Irene Schilcher, Thomas O. Eichmann, Sabine Kern, Gerhard Ledinski
Publikováno v:
Atherosclerosis. 263:e216
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c671eba13b6fddc1436dbfdc3c51a9e
https://doi.org/10.1016/j.atherosclerosis.2017.06.703
https://doi.org/10.1016/j.atherosclerosis.2017.06.703