Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Gerhard Koekemoer"'
Publikováno v:
South African Journal of Science, Vol 107, Iss 11/12 (2011)
Previous studies on gene mapping have firmly established variation in segments of the DNA structure amongst different population groups. SULT1A1 is one of four SULT1A genes that maps to the short arm of chromosome 16, and this area has been shown to
Externí odkaz:
https://doaj.org/article/4a93ebf04a7644c8b1e91e4ee475a486
Autor:
Gontse P. Moutloatse, Gerhard Koekemoer, Shayne Mason, A. Marceline van Furth, Regan Solomons, Carolus J. Reinecke, Mari van Reenen
Publikováno v:
Current Metabolomics, 2(1), 15-26. Bentham Science Publishers B.V.
Mason, S, Moutloatse, G, van Furth, A M, Solomons, R S, van Reenen, M, Reinecke, C & Koekemoer, G 2014, ' KEMREP: A New Qualitative Method for the Assessment of an Analyst’s Ability to Generate a Metabolomics Data Matrix by Gas Chromatography– Mass Spectrometry ', Current Metabolomics, vol. 2, no. 1, pp. 15-26 . https://doi.org/10.2174/2213235x02666140115214427
Mason, S, Moutloatse, G, van Furth, A M, Solomons, R S, van Reenen, M, Reinecke, C & Koekemoer, G 2014, ' KEMREP: A New Qualitative Method for the Assessment of an Analyst’s Ability to Generate a Metabolomics Data Matrix by Gas Chromatography– Mass Spectrometry ', Current Metabolomics, vol. 2, no. 1, pp. 15-26 . https://doi.org/10.2174/2213235x02666140115214427
Autor:
Lodewyk J. Mienie, Carolus J. Reinecke, Ronald J.A. Wanders, Marli Dercksen, Gerhard Koekemoer, Marinus Duran
Publikováno v:
Metabolomics, 9(4), 765-777. Springer New York
Isovaleric acidemia (IVA, MIM 248600) can be a severe and potentially life-threatening disease in affected neonates, but with a positive prognosis on treatment for some phenotypes. This study presents the first application of metabolomics to evaluate
Autor:
Gerhard Koekemoer, Roan Louw, Lodewyk J. Mienie, Carolus J. Reinecke, Izelle Smuts, Udo F. H. Engelke, Shayne Mason, Ron A. Wevers, Francois H. van der Westhuizen
Publikováno v:
Metabolomics, 9, 379-391
Metabolomics, 9, 2, pp. 379-391
Metabolomics, 9, 2, pp. 379-391
The diagnosis of respiratory chain deficiencies (RCDs) is complicated and the need for a diagnostic biomarker or biosignature has been widely expressed. In this study, the metabolic profile of a selected group of 29 RCD patients, with a predominantly
Autor:
Madelein E. Griffiths, Johannes M. Van Rooyen, Chris B. Vorster, Leoné Malan, Gerhard Koekemoer
Publikováno v:
Clinical and Experimental Hypertension. 34:363-369
Silent myocardial ischemia is a predictor of subclinical atherosclerosis driven by increased cardiovascular risk markers, although still unknown in Africans. The aim of this study was to assess if cardiovascular risk markers will be associated with s
Publikováno v:
Metabolomics. 8:1194-1203
Despite a number investigations using rapid sequencing and comparative genomic techniques, attempting to characterise the phenomenon of varying degrees of virulence within the Mycobacterium tuberculosis species, the underlying causes for this still r
Autor:
Debra Meyer, Carolus J. Reinecke, Zander Lindeque, Gerhard Koekemoer, Aurelia Alvina Williams
Publikováno v:
Metabolomics. 8:804-818
National Research Foundation; Biotechnology Partnerships and Development (BIOPAD, now called the Technology Innovation Agency); the Medical Research Council; the Centre for the Study of AIDS and the Faculty of Science at the University of Pretoria
Publikováno v:
Metabolomics. 8:17-28
Metabolomics data are typically complex and high dimensional. Multivariate dimension-reducing techniques have thus been developed for analysing metabolomics data to disclose underlying relationships, with principal component analysis (PCA) as the tec
Publikováno v:
Biochemical and Biophysical Research Communications. 401:32-36
Hereditary tyrosinemia type 1 is an autosomal recessive metabolic disorder, which is caused by a defective fumarylacetoacetate hydrolase enzyme, and consequently metabolites such as succinylacetone and p-hydroxyphenylpyruvate accumulate. We used a mo
Autor:
Gerhard Koekemoer, Jan W. H. Swanepoel
Publikováno v:
Journal of Computational and Graphical Statistics. 17:750-769
One of the main objectives of this article is to derive efficient nonparametric estimators for an unknown density fX. It is well known that the ordinary kernel density estimator has, despite several good properties, some serious drawbacks. For exampl