Výsledky vyhledávání - "Gerhard J. Leitz"

Efficacy and Safety of Rabeprazole in Children (1–11 Years) With Gastroesophageal Reflux Disease

Autor: Peter Hu, Jaroslaw Kierkus, Eduardo Tron, Gerhard J. Leitz, April Ulmer, Sheldon Sloan, Steven Silber, Ibrahim Haddad

Publikováno v: Journal of Pediatric Gastroenterology & Nutrition. 57:798-807

Evaluate the efficacy and safety of rabeprazole in children, 1 to 11 years old, with endoscopically/histologically proven gastroesophageal reflux disease (GERD).Children were randomized to 0.5- or 1.0-mg/kg rabeprazole granule formulation for 12 week

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de4d487cbe742fd11d7348f0a0a3f347
https://doi.org/10.1097/mpg.0b013e3182a4e718

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Lack of correlation of 24- vs. 48-h itraconazole minimum inhibitory concentrations with microbiological and survival outcomes in a guinea pig model of disseminated candidiasis

Autor: Luis Ostrosky-Zeichner, Zekaver Odabasi, Jose R. Rodriguez, Gerhard J. Leitz, Victor L. Paetznick, Enuo Chen, John H. Rex

Publikováno v: Mycoses. 53:438-442

Summary A ‘trailing’ effect has been commonly observed when azole antifungals are tested against Candida spp. Previous experience with fluconazole indicates that 24-h minimum inhibitory concentration (MIC) values are more compatible endpoints whe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cc91cabe6a061203e4ae156c077a5d59
https://doi.org/10.1111/j.1439-0507.2009.01733.x

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Erythropoietin is neuroprotective in models of HIV sensory neuropathy

Autor: Sanjay C. Keswani, Gerhard J. Leitz, Ahmet Hoke

Publikováno v: Neuroscience Letters. 371:102-105

HIV-associated sensory neuropathy (HIV-SN) is the most common neurological complication of HIV infection. Presently, there are no effective therapies for this painful neuropathy. The pathology of HIV-SN is characterized by 'dying back' sensory axonal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ead2fc20159c7c228d8d2428b35dc74f
https://doi.org/10.1016/j.neulet.2004.08.080

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Intravenous itraconazole for prophylaxis of systemic fungal infections in patients with acute myelogenous leukemia and high-risk myelodysplastic syndrome undergoing induction chemotherapy

Autor: Elihu H. Estey, Sherry Pierce, B. Nebiyou Bekele, Xian Zhou, Francis J. Giles, Stefan Faderl, Issam I Raad, Gerhard J. Leitz, Jo Ann Lim, Hagop M. Kantarjian, Jorge E. Cortes, Gloria Mattiuzzi, Dimitrios P. Kontoyiannis, Susan O'Brien

Publikováno v: Cancer. 100:568-573

BACKGROUND Systemic fungal infections remain the leading cause of mortality in patients with newly diagnosed acute myelogenous leukemia (AML) and high-risk myelodysplastic syndrome (MDS). The objective of the current study was to determine whether in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd35fea34713975c5d173fc13ab25132
https://doi.org/10.1002/cncr.11930

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Maintenance of efficacy and safety of rabeprazole in children with endoscopically proven GERD

Autor: Ibrahim Haddad, Steven Silber, April Ulmer, Jaroslaw Kierkus, Gerhard J. Leitz, Eduardo Tron, Sheldon Sloan, Peter Hu

Publikováno v: Journal of pediatric gastroenterology and nutrition. 58(4)

The aim of the present study was to evaluate 24-week maintenance of efficacy and safety of rabeprazole in children with endoscopically proven gastroesophageal reflux disease (GERD).Children ages 1 to 11 years who achieved endoscopic/histologic healin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11b79e248249ec59eeb540dec7e1c5f7
https://pubmed.ncbi.nlm.nih.gov/24164904

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Pharmacokinetics of Intravenous Itraconazole in Stable Hemodialysis Patients

Autor: John F. Mohr, John H. Rex, Jose R. Rodriguez, Gerhard J. Leitz, Luis Ostrosky-Zeichner, Kevin W. Finkel

Publikováno v: Antimicrobial Agents and Chemotherapy. 48:3151-3153

The pharmacokinetics of intravenous itraconazole (ITC) was studied in dialysis patients. Dialysis had no effect on the half-life and clearance of ITC or OH-ITC. However, dialysis allowed the clearance of hydroxypropyl-β-cyclodextrin (HP-β-CD). The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3edd14c26e711b5c4a638851b998486e
https://doi.org/10.1128/aac.48.8.3151-3153.2004

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Lack of correlation of 24- vs. 48-h itraconazole minimum inhibitory concentrations with microbiological and survival outcomes in a guinea pig model of disseminated candidiasis

Autor: Zekaver, Odabasi, Victor L, Paetznick, Jose R, Rodriguez, Enuo, Chen, John H, Rex, Gerhard J, Leitz, Luis, Ostrosky-Zeichner

Publikováno v: Mycoses. 53(5)

A 'trailing' effect has been commonly observed when azole antifungals are tested against Candida spp. Previous experience with fluconazole indicates that 24-h minimum inhibitory concentration (MIC) values are more compatible endpoints when compared w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9695e02001eff0bfb4424f65a767e173
https://pubmed.ncbi.nlm.nih.gov/19500259

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Open-label, randomized comparison of itraconazole versus caspofungin for prophylaxis in patients with hematologic malignancies

Autor: Gerhard J. Leitz, Elihu H. Estey, Xian Zhou, B. Nebiyou Bekele, Gladys Alvarado, Ivonne Lopez-Roman, Srdan Verstovsek, Jorge E. Cortes, Susan O'Brien, Stefan Faderl, Gloria Mattiuzzi, Issam I Raad, Francis J. Giles, Luis Ostrosky-Zeichner

Publikováno v: Antimicrobial agents and chemotherapy. 50(1)

Invasive fungal infection remains the most common cause of infectious death in acute leukemia. In this open-label, randomized study, we compared the efficacy and safety of caspofungin with that of intravenous itraconazole for antifungal prophylaxis i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac734d86d691eb39c5b682a1cdf05373
https://pubmed.ncbi.nlm.nih.gov/16377679

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A novel endogenous erythropoietin mediated pathway prevents axonal degeneration

Autor: Ulas Buldanlioglu, Sanjay C. Keswani, Nicole Reed, Hong Liang, Ahmet Hoke, Chunhua Zhou, Gerhard J. Leitz, Michelle Polley, Christelene Jack, Angela Fischer

Publikováno v: Annals of neurology. 56(6)

Clinically relevant peripheral neuropathies (such as diabetic and human immunodeficiency virus sensory neuropathies) are characterized by distal axonal degeneration, rather than neuronal death. Here, we describe a novel, endogenous pathway that preve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::426160013119648358be0ae62bed7592
https://pubmed.ncbi.nlm.nih.gov/15470751

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Intravenous and oral itraconazole versus intravenous and oral fluconazole for long-term antifungal prophylaxis in allogeneic hematopoietic stem-cell transplant recipients. A multicenter, randomized trial

Autor: Gerhard J. Leitz, Mitchell Goldman, Pranatharthi H. Chandrasekar, Mary C. Territo, Drew J. Winston, Hillard M. Lazarus, Jeffrey L. Blumer, Richard T. Maziarz

Publikováno v: Annals of internal medicine. 138(9)

Allogeneic hematopoietic stem-cell transplant recipients often receive fluconazole or an amphotericin B preparation for antifungal prophylaxis. Because of concerns about fungal resistance with fluconazole and toxicity with amphotericin B, alternative

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::470031d78b1d4fa5a3d4e2dcceedee13
https://pubmed.ncbi.nlm.nih.gov/15068993

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