Zobrazeno 1 - 10
of 428
pro vyhledávání: '"Gerhard Gründer"'
Autor:
Bruno Pedraz-Petrozzi, Moritz Spangemacher, Anton Deicher, Lena Drews, Julie Defert, Ana Yaiza Silva-Colmenero, Paul Wein, Elena Riedinger, Gerhard Gründer, Maria Gilles, Alexander Sartorius, Jonathan R. Reinwald
Publikováno v:
Frontiers in Psychiatry, Vol 15 (2024)
BackgroundNeuroinflammatory processes in depression are associated with treatment resistance to conventional antidepressants. Ketamine is an effective new therapeutic option for treatment-resistant depression (TRD). Its well-established immunomodulat
Externí odkaz:
https://doaj.org/article/b4a244cf9acf4d0e8816451713955e18
Autor:
Arnim J. Gaebler, Nilüfer Fakour, Felix Stöhr, Jana Zweerings, Arezoo Taebi, Mariia Suslova, Juergen Dukart, Joerg F. Hipp, Bhim M. Adhikari, Peter Kochunov, Suresh D. Muthukumaraswamy, Anna Forsyth, Thomas Eggermann, Florian Kraft, Ingo Kurth, Michael Paulzen, Gerhard Gründer, Frank Schneider, Klaus Mathiak
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Both, pharmacological and genome-wide association studies suggest N-methyl-D-aspartate receptor (NMDAR) dysfunction and excitatory/inhibitory (E/I)-imbalance as a major pathophysiological mechanism of schizophrenia. The identification of sha
Externí odkaz:
https://doaj.org/article/2a27b92802e64b309b19055bac2f2fa8
Autor:
Luzie Eichentopf, Christoph Hiemke, Andreas Conca, Jan Engelmann, Manfred Gerlach, Ursula Havemann-Reinecke, Gudrun Hefner, Vincenzo Florio, Maxim Kuzin, Klaus Lieb, Margareta Reis, Thomas G. Riemer, Alessandro Serretti, Georgios Schoretsanitis, Gerald Zernig, Gerhard Gründer, Xenia M. Hart
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2022)
IntroductionA titration within a certain therapeutic reference range presupposes a relationship between the blood concentration and the therapeutic effect of a drug. However, this has not been systematically investigated for escitalopram. Furthermore
Externí odkaz:
https://doaj.org/article/d11abfae948b48b08146a8a3d4e2d368
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2022)
Positron emission tomography (PET) has been used since the late 1980s for the assessment of relationships between occupancy of D2/3 receptors by antipsychotic drugs in the human brain and the clinical effects and side effects of these compounds in pa
Externí odkaz:
https://doaj.org/article/19575aa9d7e54d61a944493889d0f08a
Autor:
Cleo S. M. Funk, Xenia M. Hart, Gerhard Gründer, Christoph Hiemke, Björn Elsner, Reinhold Kreutz, Thomas G. Riemer
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2022)
Inter-individual differences in antidepressant drug concentrations attained in blood may limit the efficacy of pharmacological treatment of depressive disorders. Therapeutic drug monitoring (TDM) enables to determine drug concentrations in blood and
Externí odkaz:
https://doaj.org/article/25fecbd735b34f5bbd899fc97374ed36
Autor:
Xenia M. Hart, Luzie Eichentopf, Xenija Lense, Thomas Riemer, Katja Wesner, Christoph Hiemke, Gerhard Gründer
Publikováno v:
Frontiers in Psychiatry, Vol 12 (2021)
Background: For many psychotropic drugs, monitoring of drug concentrations in the blood (Therapeutic Drug Monitoring; TDM) has been proven useful to individualize treatments and optimize drug effects. Clinicians hereby compare individual drug concent
Externí odkaz:
https://doaj.org/article/9c2559bab1ee4d849d3f9c62798725a5
Autor:
Max Wolff, Ricarda Evens, Lea J. Mertens, Michael Koslowski, Felix Betzler, Gerhard Gründer, Henrik Jungaberle
Publikováno v:
Frontiers in Psychiatry, Vol 11 (2020)
The efficacy of psychedelic-assisted therapies for mental disorders has been attributed to the lasting change from experiential avoidance to acceptance that these treatments appear to facilitate. This article presents a conceptual model that specifie
Externí odkaz:
https://doaj.org/article/8eee16b4e1d94d96bae7b238e22da0d0
Autor:
Yoshitaka Kumakura, Albert Gjedde, Daniele Caprioli, Thorsten Kienast, Anne Beck, Michail Plotkin, Florian Schlagenhauf, Ingo Vernaleken, Gerhard Gründer, Peter Bartenstein, Andreas Heinz, Paul Cumming
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73903 (2013)
A previous study of the DOPA decarboxylase substrate 6-[(18)F]fluoro-L-DOPA (FDOPA) with positron emission tomography (PET) detected no difference of the net blood-brain transfer rate (Kin(app)) between detoxified alcoholic patients and healthy contr
Externí odkaz:
https://doaj.org/article/baa5db6b554046a09d9cb06c057a7f92
Publikováno v:
Pharmacopsychiatry. 56:73-80
Introduction Cross sectional therapeutic drug monitoring (TDM) data mining introduces new opportunities for the investigation of medication treatment effects to find optimal therapeutic windows. Medication discontinuation has been proven useful as an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::818ecc03421d2c3181338dcbdb7f2bb4
https://doi.org/10.1055/a-2039-2829
https://doi.org/10.1055/a-2039-2829
Autor:
Gerhard Gründer, Manuela Brand, Laura Kärtner, Dennis Scharf, Christian Schmitz, Moritz Spangemacher, Lea J. Mertens
Publikováno v:
Der Nervenarzt. 93:254-262
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e881b18cb38f8d6768ced270b5a8e204
https://doi.org/10.1007/s00115-021-01255-1
https://doi.org/10.1007/s00115-021-01255-1