Zobrazeno 1 - 10
of 173
pro vyhledávání: '"Gerhard Fürstenberger"'
Autor:
René Hennig, Timo Kehl, Seema Noor, Xian-Zhong Ding, Sambasiva M. Rao, Frank Bergmann, Gerhard Fürstenberger, Markus W. Büchler, Helmut Friess, Peter Krieg, Thomas E. Adrian
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 9, Iss 11, Pp 917-926 (2007)
Pancreatic cancer patients have an abysmal prognosis because of late diagnosis and lack of therapeutic options. Pancreatic intraepithelial neoplasias (PaniNs), the precursor lesions, are a potential target for chemoprevention. Targeting eicosanoid pa
Externí odkaz:
https://doaj.org/article/9c16cb6c7c9d45d2ad4270d0813265b2
Publikováno v:
Journal of Lipid Research, Vol 48, Iss 3, Pp 553-564 (2007)
Human 15-lipoxygenase (LOX)-2 and mouse 8-LOX represent orthologous members of the LOX family but display different positional specificities and tissue distribution. To study the functional role of 15-LOX-2 and 8-LOX in keratinocytes, an inducible Te
Externí odkaz:
https://doaj.org/article/f1cfd50027b9422c905643fba96138f7
Autor:
Peter Krieg, Gerhard Fürstenberger
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1841:390-400
Lipoxygenases (LOX) are key enzymes in the biosynthesis of a variety of highly active oxylipins which act as signaling molecules involved in the regulation of many biological processes. LOX are also able to oxidize complex lipids and modify membrane
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::112438923f957cda9206ff8dd8908af5
https://doi.org/10.1016/j.bbalip.2013.08.005
https://doi.org/10.1016/j.bbalip.2013.08.005
Autor:
Peter Krieg, Gerhard Fürstenberger
Publikováno v:
Lipoxygenases in Inflammation ISBN: 9783319277646
The skin is the primary barrier between the external environment and the internal milieu of the host protecting the body from physical and chemical insults and injury and preventing the loss of water. An active lipid metabolism and fatty acid-derived
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83f432502f1064001ca515498a684103
https://doi.org/10.1007/978-3-319-27766-0_8
https://doi.org/10.1007/978-3-319-27766-0_8
Autor:
P. Krieg, W. Bednar, D. Massudom, Gerhard Fürstenberger, M. Klimpfinger, I. Kalny, Lukas F. Mager, E. Bogner, T. Klampfl, Walter Berger, Brigitte Marian, Christine Heinzle, Josef Karner, Stefan Stättner
Publikováno v:
Experimental Cell Research
12(S)-Lipoxygenase (LOX) and its product 12(S)-hydroxyeicosatetraenic (HETE) acid have been implicated in angiogenesis and tumour invasion in several tumour types while their role in colorectal cancer progression has not yet been studied. We have ana
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18eb44518a68866526ba036a3d45aec0
https://doi.org/10.1016/j.yexcr.2011.12.017
https://doi.org/10.1016/j.yexcr.2011.12.017
Autor:
Karin Müller-Decker, Alexander Enk, Peter P. Nawroth, Christoffer Gebhardt, Angelika Bierhaus, Julia Németh, Jochen Hess, Gerhard Fürstenberger, Astrid Riehl, Peter Angel, Moritz Durchdewald, Bernd Arnold
Publikováno v:
The Journal of Experimental Medicine
A broad range of experimental and clinical evidence has highlighted the central role of chronic inflammation in promoting tumor development. However, the molecular mechanisms converting a transient inflammatory tissue reaction into a tumor-promoting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f548867270608c8a26894a66f4fd6c0e
https://doi.org/10.1084/jem.20070679
https://doi.org/10.1084/jem.20070679
Autor:
Frank Bergmann, Seema Noor, Sambasiva Rao, Rene Hennig, Xian-Zhong Ding, Helmut Friess, Peter Krieg, Markus W. Büchler, Thomas E. Adrian, Gerhard Fürstenberger, Timo Kehl
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 9, Iss 11, Pp 917-926 (2007)
Pancreatic cancer patients have an abysmal prognosis because of late diagnosis and lack of therapeutic options. Pancreatic intraepithelial neoplasias (PaniNs), the precursor lesions, are a potential target for chemoprevention. Targeting eicosanoid pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::428bbd88214a583621ed33b053e92f20
http://www.sciencedirect.com/science/article/pii/S1476558607800200
http://www.sciencedirect.com/science/article/pii/S1476558607800200
Publikováno v:
Experimental Dermatology. 16:445-453
Prostaglandin (PG) E(2), the predominant PG in skin, accumulates in experimentally produced mouse skin tumors. PGE(2) induces proliferation of mouse keratinocytes in vitro, epidermal hyperplasia and dysplasia, a promoted epidermis phenotype, and angi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54a6263116f078e4473ce6c89a28a1ea
https://doi.org/10.1111/j.1600-0625.2007.00549.x
https://doi.org/10.1111/j.1600-0625.2007.00549.x
Autor:
Ingrid Hausser, Silvia de Juanes, Michael Leitges, Karsten Müller, Gerhard Liebisch, Peter Krieg, Nikolas Epp, Florian Thieme, Gerd Schmitz, Gerhard Fürstenberger
Publikováno v:
The Journal of Cell Biology
12R-lipoxygenase (12R-LOX) and the epidermal LOX-3 (eLOX-3) constitute a novel LOX pathway involved in terminal differentiation in skin. This view is supported by recent studies showing that inactivating mutations in 12R-LOX and eLOX-3 are linked to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7d093d043df38e016d4f557051a457b
https://doi.org/10.1083/jcb.200612116
https://doi.org/10.1083/jcb.200612116
Publikováno v:
Journal of Lipid Research, Vol 48, Iss 3, Pp 553-564 (2007)
Human 15-lipoxygenase (LOX)-2 and mouse 8-LOX represent orthologous members of the LOX family but display different positional specificities and tissue distribution. To study the functional role of 15-LOX-2 and 8-LOX in keratinocytes, an inducible Te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8b2fb12288bdfa292cdf6cb46836a69
https://doi.org/10.1194/jlr.m600311-jlr200
https://doi.org/10.1194/jlr.m600311-jlr200