Zobrazeno 1 - 10
of 1 079
pro vyhledávání: '"Gerhard, Rogler"'
Autor:
Jacqueline Wyss, Tina Raselli, Annika Wyss, Anja Telzerow, Gerhard Rogler, Niklas Krupka, Bahtiyar Yilmaz, Thomas S. B. Schmidt, Benjamin Misselwitz
Publikováno v:
BMC Microbiology, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Liver steatosis is the most frequent liver disorder and its advanced stage, non-alcoholic steatohepatitis (NASH), will soon become the main reason for liver fibrosis and cirrhosis. The “multiple hits hypothesis” suggests that progression
Externí odkaz:
https://doaj.org/article/64a0228787cf4ef0a13a6ec4944cab18
Autor:
Carla Ammann, Rina Maqkaj, Marcel Andre Schneider, Stefanie Josefine Hehl, Ralph Fritsch, Daniel Pohl, Gerhard Rogler, Christoph Gubler, Matthias Turina, Michael Scharl
Publikováno v:
Swiss Medical Weekly, Vol 154, Iss 7 (2024)
OBJECTIVES: Colorectal carcinoma remains one of the most common malignancies worldwide. Colonoscopy screening is most effective for early detection and tumour prevention and is currently recommended in Europe for adults aged over 50 years. However, g
Externí odkaz:
https://doaj.org/article/102b9f7d63d94f5799966eaf1b2b4eb4
Autor:
Andrea Kreienbuehl, Gerhard Rogler, Burri Emanuel, Luc Biedermann, Christian Meier, Pascal Juillerat, Sophie Restellini, Peter Hruz, Stefan R. Vavricka, Daniel Aeberli, Frank Seibold
Publikováno v:
Swiss Medical Weekly, Vol 154, Iss 6 (2024)
Patients with inflammatory bowel disease (IBD) are prone to reduced bone mineral density and elevated overall fracture risk. Osteopenia affects up to 40% of patients with IBD (high regional variability). Besides disease activity, IBD specialists must
Externí odkaz:
https://doaj.org/article/e62a86297c764765b3bb445ce1658d35
Autor:
Marlene Schwarzfischer, Tano S. Ruoss, Anna Niechcial, Sung Sik Lee, Marcin Wawrzyniak, Andrea Laimbacher, Kirstin Atrott, Roberto Manzini, Marijn Wilmink, Luise Linzmeier, Yasser Morsy, Silvia Lang, Gerhard Rogler, Ralf Kaegi, Michael Scharl, Marianne R. Spalinger
Publikováno v:
Nanomaterials, Vol 14, Iss 16, p 1350 (2024)
Background: The increasing presence of plastics in the human diet is raising public concern about the potential risks posed by nanoplastic (NP) particles, which can emerge from the degradation of plastic debris. NP ingestion poses particular risks to
Externí odkaz:
https://doaj.org/article/7a341b7c98c64d56b31dd3f8a2d9dd1c
Autor:
Marie Schaad, Alain Schoepfer, Jean-Benoît Rossel, Mamadou Pathé Barry, Gerhard Rogler, Dieter Hahnloser
Publikováno v:
Medicina, Vol 60, Iss 7, p 1035 (2024)
Background and Objectives: Patients with perianal Crohn’s (CD) fistula often need repetitive surgeries and none of the established techniques was shown to be superior or preferable. Furthermore, the long-term outcome of fistula Seton drainage is no
Externí odkaz:
https://doaj.org/article/c815ca7a6b8148429b767ef41d4f1293
Autor:
Marianna Carone, Marianne R. Spalinger, Robert A. Gaultney, Raffaele Mezzenga, Kristýna Hlavačková, Aart Mookhoek, Philippe Krebs, Gerhard Rogler, Paola Luciani, Simone Aleandri
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Ulcerative colitis is a chronic inflammatory bowel disease that strongly affects patient quality of life. Side effects of current therapies necessitate new treatment strategies that maximise the drug concentration at the site of inflammation
Externí odkaz:
https://doaj.org/article/2d75cfd0314f4f04b7c907fb1bf398fb
Autor:
Fionä Caratis, Mikołaj Opiełka, Martin Hausmann, Maria Velasco-Estevez, Bartłomiej Rojek, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Bartosz Karaszewski, Aleksandra Rutkowska
Publikováno v:
PLoS ONE, Vol 19, Iss 3, p e0283060 (2024)
Acidosis is one of the hallmarks of demyelinating central nervous system (CNS) lesions in multiple sclerosis (MS). The response to acidic pH is primarily mediated by a family of G protein-coupled proton-sensing receptors: OGR1, GPR4 and TDAG8. These
Externí odkaz:
https://doaj.org/article/ec819292dc9944ad9a7599de537dd7fa
Autor:
Fabienne Kurt, Gabriel E. Leventhal, Marianne Rebecca Spalinger, Laura Anthamatten, Philipp Rogalla von Bieberstein, Carmen Menzi, Markus Reichlin, Marco Meola, Florian Rosenthal, Gerhard Rogler, Christophe Lacroix, Tomas de Wouters
Publikováno v:
Gut Microbes, Vol 15, Iss 1 (2023)
ABSTRACTThe success of fecal microbiota transplants (FMT) has provided the necessary proof-of-concept for microbiome therapeutics. Yet, feces-based therapies have many associated risks and uncertainties, and hence defined microbial consortia that mod
Externí odkaz:
https://doaj.org/article/90151f7cd74f4bf8aed4068ee8ff03a9
Autor:
Severin A. Lautenschlager, Mamadou Pathé Barry, Gerhard Rogler, Luc Biedermann, Philipp Schreiner, Alexander R. Siebenhüner, Swiss IBD Cohort Study Group
Publikováno v:
BMC Gastroenterology, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Background Various environmental risk factors have been associated with the pathogenesis of inflammatory bowel disease. In this study we aimed to identify lifestyle factors that affect the onset of Crohn’s disease and ulcerative colitis. M
Externí odkaz:
https://doaj.org/article/050e64a7b7204c5d8e745f68f1130a31
Autor:
Janine Häfliger, Marlene Schwarzfischer, Kirstin Atrott, Claudia Stanzel, Yasser Morsy, Marcin Wawrzyniak, Silvia Lang, Tomas Valenta, Konrad Basler, Gerhard Rogler, Michael Scharl, Marianne R. Spalinger
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 15, Iss 3, Pp 717-739 (2023)
Background & Aims: Glycoprotein (GP)96 is an endoplasmic reticulum–resident master chaperone for cell surface receptors including the Wnt co-receptors low-density lipoprotein-receptor–related protein 5/6. Intestinal epithelial cell (IEC)-specific
Externí odkaz:
https://doaj.org/article/9a20e5b0ea1a40e19da95551ede99806