Zobrazeno 1 - 10
of 636
pro vyhledávání: '"Gerhard, Opelz"'
Autor:
Matthias Schaier, Christian Morath, Lei Wang, Christian Kleist, Gerhard Opelz, Thuong Hien Tran, Sabine Scherer, Lien Pham, Naruemol Ekpoom, Caner Süsal, Gerald Ponath, Florian Kälble, Claudius Speer, Louise Benning, Christian Nusshag, Christoph F. Mahler, Luiza Pego da Silva, Claudia Sommerer, Angela Hückelhoven-Krauss, David Czock, Arianeb Mehrabi, Constantin Schwab, Rüdiger Waldherr, Paul Schnitzler, Uta Merle, Vedat Schwenger, Markus Krautter, Stephan Kemmner, Michael Fischereder, Manfred Stangl, Ingeborg A. Hauser, Anna-Isabelle Kälsch, Bernhard K. Krämer, Georg A. Böhmig, Carsten Müller-Tidow, Jochen Reiser, Martin Zeier, Michael Schmitt, Peter Terness, Anita Schmitt, Volker Daniel
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundThe administration of modified immune cells (MIC) before kidney transplantation led to specific immunosuppression against the allogeneic donor and a significant increase in regulatory B lymphocytes. We wondered how this approach affected th
Externí odkaz:
https://doaj.org/article/e8a3a583d0ee42d7b2d399e91afea0aa
Autor:
Eman H Ibrahim, Mostafa Aly, Christian Morath, Douaa M Sayed, Naruemol Ekpoom, Gerhard Opelz, Caner Süsal, Volker Daniel
Publikováno v:
Immunity, Inflammation and Disease, Vol 9, Iss 4, Pp 1252-1271 (2021)
Abstract Objectives Regulatory B cells (Bregs) and T cells (Tregs) are thought to be involved in the regulation of graft acceptance in renal transplant recipients. However, mechanisms that affect Breg differentiation and interaction with Tregs are ra
Externí odkaz:
https://doaj.org/article/1ff313b744e84b828f6c6c0efd04c5d6
Autor:
Lei Wang, Arianeb Mehrabi, Maria-Luisa Schubert, Anita Schmitt, Brigitte Neuber, Alexander Kunz, Angela Hückelhoven-Krauss, Carsten Müller-Tidow, Michael Schmitt, Christian Morath, Martin Zeier, Constantin Schwab, Anja Sander, Sabine Scherer, Claudius Speer, Christian Kleist, Claudia Sommerer, Florian Kälble, Christian Nusshag, Matthias Schaier, Louise Benning, Vedat Schwenger, Caner Süsal, Gerhard Opelz, T. Hien Tran, Stephan Kemmner, Michael Fischereder, Manfred Stangl, Ingeborg A. Hauser, Christian Bischofs, Sandra Sauer, Rüdiger Waldherr, Christopher Büsch, David Czock, Georg A Böhmig, Jochen Reiser, Axel Roers, Peter Terness, Volker Daniel
Publikováno v:
BMJ Open, Vol 12, Iss 11 (2022)
Introduction Donor-derived modified immune cells (MIC) induced long-term specific immunosuppression against the allogeneic donor in preclinical models of transplantation. In a phase I clinical trial (TOL-1 Study), MIC treatment resulted in a cellular
Externí odkaz:
https://doaj.org/article/6362680b60bd43139a9d0cb0059a65b3
Autor:
Eman H. Ibrahim, Mostafa G. Aly, Gerhard Opelz, Christian Morath, Martin Zeier, Caner Süsal, Douaa M. Sayed, Eman Hassan, Naruemol Ekpoom, Volker Daniel
Publikováno v:
BMC Nephrology, Vol 22, Iss 1, Pp 1-13 (2021)
Abstract Background The Identification of B cell subsets with regulatory functions might open the way to new therapeutic strategies in the field of transplantation, which aim to reduce the dose of immunosuppressive drugs and prolong the graft surviva
Externí odkaz:
https://doaj.org/article/c4ae3619c3204b3e878997fc8f37957b
Autor:
Mostafa G. Aly, Eman H. Ibrahim, Hristos Karakizlis, Rolf Weimer, Gerhard Opelz, Christian Morath, Martin Zeier, Naruemol Ekpoom, Volker Daniel
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
IntroductionGaps still exist regarding knowledge on regulatory cells in transplant recipients. We studied the phenotypic patterns of CD4+, CD8+CD28- Tregs, and CD19+IL-10+ Bregs in the blood of healthy controls (HC), end-stage kidney disease patients
Externí odkaz:
https://doaj.org/article/8e845bd7cc804384bc930c0c873adb99
Autor:
Li Zhu, Mostafa Aly, Ruben Jeremias Kuon, Bettina Toth, Haihao Wang, Hristos Karakizlis, Rolf Weimer, Christian Morath, Eman Ibrahim, Naruemol Ekpoom, Gerhard Opelz, Volker Daniel
Publikováno v:
BMC Immunology, Vol 20, Iss 1, Pp 1-15 (2019)
Abstract Background Previously, we demonstrated up-regulated activated CD4+ and CD8+ T lymphocytes as well as up-regulated cytotoxic NK cells in the blood of patients with idiopathic recurrent miscarriage. In the present study, we tried to identify d
Externí odkaz:
https://doaj.org/article/2b8bde390034493c8e313a14e7aa3170
Autor:
Christian, Morath, Matthias, Schaier, Eman, Ibrahim, Lei, Wang, Christian, Kleist, Gerhard, Opelz, Caner, Süsal, Gerald, Ponath, Mostafa, Aly, Cristiam, Alvarez, Florian, Kälble, Claudius, Speer, Louise, Benning, Christian, Nusshag, Luiza Pego, da Silva, Claudia, Sommerer, Angela, Hückelhoven-Krauss, David, Czock, Arianeb, Mehrabi, Constantin, Schwab, Rüdiger, Waldherr, Paul, Schnitzler, Uta, Merle, Thuong Hien, Tran, Sabine, Scherer, Georg, Boehmig, Carsten, Müller-Tidow, Jochen, Reiser, Anita, Schmitt, Martin, Zeier, Michael, Schmitt, Peter, Terness, Volker, Daniel
Publikováno v:
Journal of the American Society of Nephrology. 34:160-174
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9b799aad78abf85ea0be245339a600d
https://doi.org/10.1681/asn.2022020210
https://doi.org/10.1681/asn.2022020210
Autor:
Caner Süsal, Bernd Döhler, Andrea Ruhenstroth, Christian Morath, Antonij Slavcev, Thomas Fehr, Eric Wagner, Bernd Krüger, Margaret Rees, Sanja Balen, Stela Živčić-Ćosić, Douglas J. Norman, Dirk Kuypers, Marie-Paule Emonds, Przemyslaw Pisarski, Claudia Bösmüller, Rolf Weimer, Joannis Mytilineos, Sabine Scherer, Thuong H. Tran, Petra Gombos, Peter Schemmer, Martin Zeier, Gerhard Opelz
Publikováno v:
EBioMedicine, Vol 9, Iss C, Pp 366-371 (2016)
Background: It is an unresolved issue why some kidney transplant recipients with pretransplant donor-specific HLA antibodies (DSA) show a high transplant failure rate, whereas in other patients DSA do not harm the graft. We investigated whether help
Externí odkaz:
https://doaj.org/article/d8fac3df054742369a5e2c36fac9cbc6
Publikováno v:
Transplantation Direct, Vol 4, Iss 7, p e365 (2018)
Background. Even in the modern era of kidney transplantation with improved surgical techniques, immunosuppression, and clinical care, HLA matching has been shown to be important in allograft survival in adults who receive an organ from either a decea
Externí odkaz:
https://doaj.org/article/fb2d175ea1ef431f80485273f1251f84
Autor:
Christian Morath, Anita Schmitt, Michael Schmitt, Lei Wang, Christian Kleist, Gerhard Opelz, Caner Süsal, T. Hien Tran, Sabine Scherer, Vedat Schwenger, Stephan Kemmner, Michael Fischereder, Manfred Stangl, Ingeborg A. Hauser, Claudia Sommerer, Christian Nusshag, Florian Kälble, Claudius Speer, Louise Benning, Christian Bischofs, Sandra Sauer, Maria-Luisa Schubert, Alexander Kunz, Angela Hückelhoven-Krauss, Brigitte Neuber, Arianeb Mehrabi, Constantin Schwab, Rüdiger Waldherr, Anja Sander, Christopher Büsch, David Czock, Georg A Böhmig, Jochen Reiser, Axel Roers, Carsten Müller-Tidow, Peter Terness, Martin Zeier, Volker Daniel, Matthias Schaier
Publikováno v:
BMJ Open
Introduction: donor-derived modified immune cells (MIC) induced long-term specific immunosuppression against the allogeneic donor in preclinical models of transplantation. In a phase I clinical trial (TOL-1 Study), MIC treatment resulted in a cellula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdae35ecb3897be27de7aeaa3db10e71
https://pubmed.ncbi.nlm.nih.gov/36368749
https://pubmed.ncbi.nlm.nih.gov/36368749