Zobrazeno 1 - 10
of 403
pro vyhledávání: '"Gerhard, Bauer"'
Autor:
Susanna S. Park, MD, PhD, Gerhard Bauer, Brian Fury, MS, Mehrdad Abedi, MD, Nicholas Perotti, MD, Dane Colead-Bergum, MA, Jan A. Nolta, PhD
Publikováno v:
Ophthalmology Science, Vol 5, Iss 1, Pp 100589- (2025)
Purpose: To evaluate the feasibility and safety of intravitreal injection of autologous CD34+ stem cells from bone marrow (BMSCs) in eyes with vision loss from retinitis pigmentosa (RP). Design: Phase I prospective, open-label, single-center study. P
Externí odkaz:
https://doaj.org/article/be2b2d0c7beb4b80a5ba13ef531f448f
Autor:
Laura Schnetzer, Jürgen Steinbacher, Gerhard Bauer, Alexander Baden Kunz, Jürgen Bergmann, Martin Kronbichler, Eugen Trinka, Mark McCoy
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 16 (2023)
The locked-in syndrome (LiS) is defined as the loss of most voluntary muscle movements with preserved cognitive abilities due to a ventral pontine lesion. However, some patients may also have severe impairment of consciousness [locked-in plus syndrom
Externí odkaz:
https://doaj.org/article/51744a2da65d49a3b0f7d827408ed7e2
Autor:
Deepak Bhere, Sung Hugh Choi, Pim van de Donk, David Hope, Kiki Gortzak, Amina Kunnummal, Jasneet Khalsa, Esther Revai Lechtich, Clemens Reinshagen, Victoria Leon, Nabil Nissar, Wenya Linda Bi, Cheng Feng, Hongbin Li, Yu Shrike Zhang, Steven H. Liang, Neil Vasdev, Walid Ibn Essayed, Pablo Valdes Quevedo, Alexandra Golby, Naima Banouni, Anna Palagina, Reza Abdi, Brian Fury, Stelios Smirnakis, Alarice Lowe, Brock Reeve, Arthur Hiller, E. Antonio Chiocca, Glenn Prestwich, Hiroaki Wakimoto, Gerhard Bauer, Khalid Shah
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Abstract Cellular therapies offer a promising therapeutic strategy for the highly malignant brain tumor, glioblastoma (GBM). However, their clinical translation is limited by the lack of effective target identification and stringent testing in pre-cl
Externí odkaz:
https://doaj.org/article/c3728edd112e43e6baeb95ff129c6000
Autor:
Gerhard Bauer, Joseph S. Anderson
This Brief describes the concept and realization of gene therapy for HIV from the unique historic perspective and insight of two pioneers of the clinical applications of stem cell gene therapy for HIV.Gerhard Bauer applied ribozyme-anti-HIV and other
Autor:
Mohamed Abou-el-Enein, Aris Angelis, Frederick R. Appelbaum, Nancy C. Andrews, Susan E. Bates, Arlene S. Bierman, Malcolm K. Brenner, Marina Cavazzana, Michael A. Caligiuri, Hans Clevers, Emer Cooke, George Q. Daley, Victor J. Dzau, Lee M. Ellis, Harvey V. Fineberg, Lawrence S.B. Goldstein, Stephen Gottschalk, Margaret A. Hamburg, Donald E. Ingber, Donald B. Kohn, Adrian R. Krainer, Marcela V. Maus, Peter Marks, Christine L. Mummery, Roderic I. Pettigrew, Joni L. Rutter, Sarah A. Teichmann, Andre Terzic, Fyodor D. Urnov, David A. Williams, Jedd D. Wolchok, Mark Lawler, Cameron J. Turtle, Gerhard Bauer, John P.A. Ioannidis
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 22, Iss , Pp 11-14 (2021)
Externí odkaz:
https://doaj.org/article/c3fa45c6e32349f68ffd7fcab701dc16
Autor:
Peter Belafsky, Shannon M Clayton, Joehleen A Archard, Jordan P Pavlic, Shyam Rao, D Gregory Farwell, Maggie Kuhn, Peter Deng, Julian Halmai, Gerhard Bauer, Kyle D Fink, Brian Fury, Nicholas H Perotti, Jon E Walker, Angela M Beliveau, Andrew Birkeland, Marianne Abouyared, Whitney Cary, Jan A Nolta, Johnathon D Anderson
Publikováno v:
Journal of Medical Sciences, Vol 41, Iss 4, Pp 201-210 (2021)
Approximately 50% of oncology patients receive radiotherapy, with the dose of radiation often being limited to mitigate normal tissue damage of proximal critical/sensitive structures. Currently, no preclinical models exist to study a putative drug's
Externí odkaz:
https://doaj.org/article/6ce166ed881d47c89cfef8aae0ed21ab
Autor:
Gerson D. Hernandez, Christine M. Solinsky, Wendy J. Mack, Naoko Kono, Kathleen E. Rodgers, Chun‐Yi Wu, Ana R. Mollo, Claudia M. Lopez, Sonia Pawluczyk, Gerhard Bauer, Dawn Matthews, Yonggang Shi, Meng Law, Michael A. Rogawski, Lon S. Schneider, Roberta D. Brinton
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 6, Iss 1, Pp n/a-n/a (2020)
Abstract Introduction Allopregnanolone is an endogenous neurosteroid with the potential to be a novel regenerative therapeutic for Alzheimer's disease (AD). Foundations of mechanistic understanding and well‐established preclinical safety efficacy m
Externí odkaz:
https://doaj.org/article/5850674a3da74dfebad3206ffcd3f5dc
Publikováno v:
Stem Cells Translational Medicine, Vol 7, Iss 9, Pp 676-685 (2018)
Abstract The promise of stem cell (SC) therapies to restore functions of damaged tissues and organs brings enormous hope to patients, their families, loved ones, and caregivers. However, limits may exist for which indications SC therapies might be us
Externí odkaz:
https://doaj.org/article/f515164d21144454bf21609077a79dc3
Autor:
Jack C. Reidling, Aroa Relaño-Ginés, Sandra M. Holley, Joseph Ochaba, Cindy Moore, Brian Fury, Alice Lau, Andrew H. Tran, Sylvia Yeung, Delaram Salamati, Chunni Zhu, Asa Hatami, Carlos Cepeda, Joshua A. Barry, Talia Kamdjou, Alvin King, Dane Coleal-Bergum, Nicholas R. Franich, Frank M. LaFerla, Joan S. Steffan, Mathew Blurton-Jones, Charles K. Meshul, Gerhard Bauer, Michael S. Levine, Marie-Francoise Chesselet, Leslie M. Thompson
Publikováno v:
Stem Cell Reports, Vol 10, Iss 1, Pp 58-72 (2018)
Summary: Huntington's disease (HD) is an inherited neurodegenerative disorder with no disease-modifying treatment. Expansion of the glutamine-encoding repeat in the Huntingtin (HTT) gene causes broad effects that are a challenge for single treatment
Externí odkaz:
https://doaj.org/article/6a20e0b98a194e96bbd0862727f88f6d
Autor:
Barbara Savoldo, Gerhard Bauer, Brian G. Till, Peter Marks, Helen E. Heslop, Andrew D. Fesnak, Steven A. Feldman, Magdi Elsallab, Mohamed Abou-el-Enein
Supplementary Data from Scalable Manufacturing of CAR T Cells for Cancer Immunotherapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40c9f72194e95c7d56059a0c2e79e392
https://doi.org/10.1158/2643-3230.22543887
https://doi.org/10.1158/2643-3230.22543887