The novel pre-rRNA detection workflow “Riboprobing” allows simple identification of undescribed RNA species

Autor: Gerhalter, Magdalena, Kofler, Lisa, Zisser, Gertrude, Merl-Pham, Juliane, Hauck, Stefanie M., Bergler, Helmut

Publikováno v: RNA; 2024, Vol. 30 Issue: 7 p807-823, 17p

The novel ribosome biogenesis inhibitor usnic acid blocks nucleolar pre-60S maturation.

Autor: Kofler L; Institute of Molecular Biosciences, University of Graz, Graz, 8010, Austria., Grundmann L; Research Institute of Molecular Pathology (IMP), Vienna BioCenter, Vienna, 1030, Austria.; Vienna BioCenter PhD Program, Doctoral School of the University of Vienna and Medical University of Vienna, 1030, Vienna, Austria., Gerhalter M; Institute of Molecular Biosciences, University of Graz, Graz, 8010, Austria., Prattes M; Institute of Molecular Biosciences, University of Graz, Graz, 8010, Austria., Merl-Pham J; Core Facility Metabolomics and Proteomics (CF-MPC), Helmholtz Center Munich, German Center for Environmental Health GmbH, D-80939, Munich, Germany., Zisser G; Institute of Molecular Biosciences, University of Graz, Graz, 8010, Austria., Grishkovskaya I; Research Institute of Molecular Pathology (IMP), Vienna BioCenter, Vienna, 1030, Austria., Hodirnau VV; Institute of Science and Technology Austria, Klosterneuburg, Austria., Vareka M; Institute of Organic Chemistry, Graz University of Technology, Stremayrgasse 9, Graz, 8010, Austria., Breinbauer R; Institute of Organic Chemistry, Graz University of Technology, Stremayrgasse 9, Graz, 8010, Austria., Hauck SM; Core Facility Metabolomics and Proteomics (CF-MPC), Helmholtz Center Munich, German Center for Environmental Health GmbH, D-80939, Munich, Germany., Haselbach D; Research Institute of Molecular Pathology (IMP), Vienna BioCenter, Vienna, 1030, Austria. david.haselbach@imp.ac.at., Bergler H; Institute of Molecular Biosciences, University of Graz, Graz, 8010, Austria. helmut.bergler@uni-graz.at.

Publikováno v: Nature communications [Nat Commun] 2024 Aug 29; Vol. 15 (1), pp. 7511. Date of Electronic Publication: 2024 Aug 29.