Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Gergely Kali"'
Enhanced Mucoadhesion of Thiolated β‑Cyclodextrin by S‑Protection with 2‑Mercaptoethanesulfonic Acid
Autor:
Gergely Kali, Ali Magdi Mahmoud Mahmoud Taha, Emiliano Campanella, Martyna Truszkowska, Soheil Haddadzadegan, Nunzio Denora, Andreas Bernkop-Schnürch
Publikováno v:
ACS Omega, Vol 9, Iss 5, Pp 5819-5828 (2024)
Externí odkaz:
https://doaj.org/article/c9c0802d02884772b80a8738a1a103e4
Publikováno v:
Pharmaceutics, Vol 15, Iss 7, p 1993 (2023)
Aim: This study aims to design a novel thiolated κ-carrageenan (κ-CA-SH) and evaluate its potential as an excipient for the design of mucoadhesive drug delivery systems. Methods: Native κ-carrageenan (κ-CA) was thiolated with phosphorous pentasul
Externí odkaz:
https://doaj.org/article/c6b802d5d6e84ae4a969ac917afea84b
Autor:
Brunella Grassiri, Andrea Cesari, Federica Balzano, Chiara Migone, Gergely Kali, Andreas Bernkop-Schnürch, Gloria Uccello-Barretta, Ylenia Zambito, Anna Maria Piras
Publikováno v:
Polymers, Vol 14, Iss 15, p 3170 (2022)
Thiolated cyclodextrins are structurally simple mucoadhesive macromolecules, which are able to host drugs and increase their apparent water solubility, as well as interact with the mucus layer prolonging drug residence time on the site of absorption.
Externí odkaz:
https://doaj.org/article/256c08a5f7834a9aac957f09c907fd55
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 13, Iss 1, Pp 1310-1315 (2017)
The aqueous reversible addition fragmentation chain-transfer (RAFT) copolymerization of isoprene and bulky comonomers, an acrylate and an acrylamide in the presence of methylated β-cyclodextrin was employed for the first time to synthesize block-cop
Externí odkaz:
https://doaj.org/article/50abfe9f5c084e41943d30653dd0c484
Publikováno v:
CHIMIA, Vol 66, Iss 1-2 (2012)
Externí odkaz:
https://doaj.org/article/149d9de4174e4c5c8117ea1232068b1f
Autor:
Dennis To, Anant Kakar, Gergely Kali, Richard Wibel, Patrick Knoll, Florentine Marx, Andreas Bernkop-Schnürch
Publikováno v:
Journal of Colloid and Interface Science. 630:164-178
Aminoglycosides are well known, cationic antimicrobial drugs. However, biofilm-based antibiotic resistance significantly limits their efficacy. Masking the polycationic character of these drugs, followed by incorporation into self-emulsifying drug de
Autor:
Andrea, Fürst, Iram, Shahzadi, Zeynep, Burcu Akkuş-Dağdeviren, Gergely, Kali, Andrea, Hupfauf, Ronald, Gust, Andreas, Bernkop-Schnürch
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 181:292-299
The aim of this study was the synthesis and evaluation of entirely S-protected thiolated hydroxyethylcellulose (HEC) with low and high viscosity, as well as thiolated poly-L-lysine (poly-L-Lys) used as dual-acting ionic as well as thiol-disulfide exc
Autor:
Nguyet-Minh Nguyen Le, Sarah Zsák, Bao Le-Vinh, Julian David Friedl, Gergely Kali, Patrick Knoll, Hartwig Wolfram Seitter, Alexandra Koschak, Andreas Bernkop-Schnürch
Publikováno v:
ACS Applied Materials & Interfaces. 14:44981-44991
This study aimed to develop phosphatase-responsive ζ potential converting nanocarriers utilizing polyphosphate-coated cell-penetrating peptide (CPP)-decorated nanoemulsions (NEs) as a novel gene delivery system to retinal cells.Poly-l-lysine (PLL) w
Autor:
Rahul Kumar, Amit K. Thakur, Gergely Kali, Kancharlapalli Chinaraga Pitchaiah, Raj Kumar Arya, Anurag Kulabhi
Publikováno v:
Drug delivery and translational research.
The low aqueous solubility and subsequently slow dissolution rate, as well as the poor bioavailability of several active pharmaceutical ingredients (APIs), are major challenges in the pharmaceutical industry. In this review, the particle engineering
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 180
The aim of this study was to improve the mucoadhesive properties of hydroxyethyl cellulose (HEC) via the covalent attachment of betaine. Synthesis was carried out through esterification of HEC utilizing N-chlorobetainyl chloride. Betaine-modified HEC