Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Gergana Zahmanova"'
Publikováno v:
Viruses, Vol 16, Iss 5, p 684 (2024)
The hepatitis E virus is a serious health concern worldwide, with 20 million cases each year. Growing numbers of autochthonous HEV infections in industrialized nations are brought on via the zoonotic transmission of HEV genotypes 3 and 4. Pigs and wi
Externí odkaz:
https://doaj.org/article/6ff67d5eac1749f0b177c38f0e140d61
Autor:
Gergana Zahmanova, Katerina Takova, Valeria Tonova, Tsvetoslav Koynarski, Laura L. Lukov, Ivan Minkov, Maria Pishmisheva, Stanislav Kotsev, Ilia Tsachev, Magdalena Baymakova, Anton P. Andonov
Publikováno v:
Viruses, Vol 15, Iss 7, p 1558 (2023)
Hepatitis E virus (HEV) is one of the leading causes of acute viral hepatitis. Transmission of HEV mainly occurs via the fecal-oral route (ingesting contaminated water or food) or by contact with infected animals and their raw meat products. Some ani
Externí odkaz:
https://doaj.org/article/8483b76e2c264918964b9e7f5b380c16
Autor:
Ilia Tsachev, Krasimira Gospodinova, Roman Pepovich, Katerina Takova, Todor Kundurzhiev, Gergana Zahmanova, Kristin Kaneva, Magdalena Baymakova
Publikováno v:
Viruses, Vol 15, Iss 7, p 1594 (2023)
In recent years, hepatitis E virus (HEV) infection has been found to be widespread among different animal species worldwide. In Bulgaria, high HEV seropositivity was found among pigs (60.3%), wild boars (40.8%), and East Balkan swine (82.5%). The aim
Externí odkaz:
https://doaj.org/article/7dcb742b3c594d05b46dd77a333f6663
Autor:
Gergana Zahmanova, Katerina Takova, Rumyana Valkova, Valentina Toneva, Ivan Minkov, Anton Andonov, Georgi L. Lukov
Publikováno v:
Life, Vol 12, Iss 2, p 156 (2022)
Emerging and re-emerging zoonotic diseases cause serious illness with billions of cases, and millions of deaths. The most effective way to restrict the spread of zoonotic viruses among humans and animals and prevent disease is vaccination. Recombinan
Externí odkaz:
https://doaj.org/article/2bb71954fdf34264acc74cba51b898c9
Autor:
Katerina Takova, Tsvetoslav Koynarski, George Minkov, Valentina Toneva, Eugenia Mardanova, Nikolai Ravin, Georgi L. Lukov, Gergana Zahmanova
Publikováno v:
Vaccines, Vol 9, Iss 9, p 991 (2021)
Hepatitis E is an emerging global disease, mainly transmitted via the fecal–oral route in developing countries, and in a zoonotic manner in the developed world. Pigs and wild boar constitute the primary Hepatitis E virus (HEV) zoonotic reservoir. C
Externí odkaz:
https://doaj.org/article/a58b28eecd9449daac6629310f155372
Autor:
Gergana Zahmanova, Milena Mazalovska, Katerina Takova, Valentina Toneva, Ivan Minkov, Hadrien Peyret, George Lomonossoff
Publikováno v:
Life, Vol 11, Iss 1, p 64 (2021)
The core antigen of hepatitis B virus (HBcAg) is capable of self-assembly into virus-like particles (VLPs) when expressed in a number of heterologous systems. Such VLPs are potential carriers of foreign antigenic sequences for vaccine design. In this
Externí odkaz:
https://doaj.org/article/0225d3a7c678437abf9cc13f97102b28
Autor:
Katerina Takova, Tsvetoslav Koynarski, Ivan Minkov, Zdravka Ivanova, Valentina Toneva, Gergana Zahmanova
Publikováno v:
Animals, Vol 10, Iss 9, p 1521 (2020)
(1) Background: Hepatitis E virus (HEV) is a causative agent of acute viral hepatitis, predominantly transmitted by the fecal–oral route. In developed countries, HEV is considered to be an emerging pathogen since the number of autochthonous cases i
Externí odkaz:
https://doaj.org/article/7f5f8b6679bb46d8b8029707f9642849
Autor:
Eugenia S. Mardanova, Roman Y. Kotlyarov, Maya D. Stuchinskaya, Lyudmila I. Nikolaeva, Gergana Zahmanova, Nikolai V. Ravin
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 24; Pages: 15684
Capsid protein of Hepatitis E virus (HEV) is capable of self-assembly into virus-like particles (VLPs) when expressed in Nicotiana benthamiana plants. Such VLPs could be used as carriers of antigens for vaccine development. In this study, we obtained
Publikováno v:
Plant Biotechnology Journal
We have investigated the use of transient expression to produce virus-like particles (VLPs) of severe acute respiratory syndrome coronavirus 2, the causative agent of COVID-19, in Nicotiana benthamiana. Expression of a native form of the spike (S) pr
Autor:
Gergana Zahmanova, Alaa A. Aljabali, Katerina Takova, Valentina Toneva, Murtaza M. Tambuwala, Anton P. Andonov, Georgi L. Lukov, Ivan Minkov
Publikováno v:
International Journal of Molecular Sciences. 24:1533
Plant viruses have traditionally been studied as pathogens in the context of understanding the molecular and cellular mechanisms of a particular disease affecting crops. In recent years, viruses have emerged as a new alternative for producing biologi