Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Gergő Mótyán"'
Autor:
Gergő Mótyán, László Mérai, Márton Attila Kiss, Zsuzsanna Schelz, Izabella Sinka, István Zupkó, Éva Frank
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 2589-2596 (2018)
Multistep syntheses of novel 17β-pyrazol-5'-ones in the Δ5-androstane series were efficiently carried out from pregnenolone acetate. A steroidal 17-carboxylic acid was first synthesized as a norpregnene precursor by the bromoform reaction and subse
Externí odkaz:
https://doaj.org/article/f9a17cab8b254c7e9580fb8e06d3e1b2
Autor:
Gergő Mótyán, Ádám Baji, Małgorzata Anna Marć, Mohana Krishna Gopisetty, Dóra I. Adamecz, Mónika Kiricsi, Éva A. Enyedy, Éva Frank
Publikováno v:
Applied Sciences, Vol 10, Iss 1, p 229 (2019)
Taking into account the pharmacological relevance of heterocycle-fused natural steroids, the objective of the current study was to develop a multistep reaction sequence for the efficient synthesis of novel D-ring-condensed 5-amino-1-arylpyrazoles fro
Externí odkaz:
https://doaj.org/article/fa472267a0364580a33e5b289a4d108a
Publikováno v:
Molecules, Vol 24, Iss 3, p 569 (2019)
Microwave-assisted syntheses of novel ring d-condensed 2-pyrazolines in the estrone series were efficiently carried out from steroidal α,β-enones and hydrazine derivatives. The ring-closure reaction of 16-benzylidene estrone 3-methyl ether with hyd
Externí odkaz:
https://doaj.org/article/73bbe660ad53452aafbc3e76af138a31
Autor:
Miroslav Peřina, Márton A. Kiss, Gergő Mótyán, Eva Szczyrbová, Martin Eliáš, Vladimír Študent, Daniela Kurfurstová, Markéta Kovalová, Lukáš Mada, Jan Bouchal, Éva Frank, Radek Jorda
High expression of the androgen receptor (AR) and the disruption of its regulation are strongly responsible for the development of prostate cancer (PCa). Therapeutically relevant non-steroidal or steroidal antiandrogens are able to block the AR effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ee539e9d7d65a76ef251939759ee609
https://doi.org/10.1101/2022.12.17.520850
https://doi.org/10.1101/2022.12.17.520850
Autor:
Barnabás Molnár, Njangiru Isaac Kinyua, Gergő Mótyán, Péter Leits, István Zupkó, Renáta Minorics, György T. Balogh, Éva Frank
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 219:106064
The unique estrogen receptor (ER)-independent antiproliferative and apoptotic activity of 2-methoxyestradiol (2ME2) is well known, however, its use has been limited because of its poor oral bioavailability. In this study, novel 2-aminomethylated estr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8991f28e753562c646b7e28e678432e
https://doi.org/10.1016/j.jsbmb.2022.106064
https://doi.org/10.1016/j.jsbmb.2022.106064
Autor:
Dóra Izabella Adamecz, Ádám Baji, Małgorzata Anna Marć, Mohana Krishna Gopisetty, Gergő Mótyán, Éva A. Enyedy, Mónika Kiricsi, Éva Frank
Publikováno v:
Applied Sciences
Volume 10
Issue 1
Applied Sciences, Vol 10, Iss 1, p 229 (2019)
Volume 10
Issue 1
Applied Sciences, Vol 10, Iss 1, p 229 (2019)
Taking into account the pharmacological relevance of heterocycle-fused natural steroids, the objective of the current study was to develop a multistep reaction sequence for the efficient synthesis of novel D-ring-condensed 5-amino-1-arylpyrazoles fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a5b9b64144e577ec6b129a8dda7c507
Publikováno v:
Molecules
Volume 24
Issue 3
Molecules, Vol 24, Iss 3, p 569 (2019)
Volume 24
Issue 3
Molecules, Vol 24, Iss 3, p 569 (2019)
Microwave-assisted syntheses of novel ring d-condensed 2-pyrazolines in the estrone series were efficiently carried out from steroidal α,β-enones and hydrazine derivatives. The ring-closure reaction of 16-benzylidene estrone 3-methyl ether with hyd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a425e8d109d641b32146311c3886645b
Publikováno v:
Journal of Molecular Structure. 1110:143-149
Efficient syntheses of some pregnane-fused isoxazolines from 16-dehydropregnenolone acetate with different arylnitrile oxides were carried out by 1,3-dipolar cycloadditions. The intermolecular ring-closures occurred in a highly regio- and stereoselec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59691b40a230278bcd21d4df1ae298f3
https://doi.org/10.1016/j.molstruc.2016.01.050
https://doi.org/10.1016/j.molstruc.2016.01.050
Autor:
Imre Ocsovszki, Ádám Baji, János Wölfling, Éva Frank, Gergő Mótyán, Ferenc Kovács, István Zupkó, Gyula Schneider, Izabella Sinka
Publikováno v:
Steroids. 126
Novel androstanopyrazoles have been efficiently synthesized from steroidal β-ketoaldehydes with different arylhydrazine hydrochlorides both under acidic and basic conditions. Knorr-type transformations of 16-hydroxymethylene-dehydroepiandrosterone c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3935fac09965a40599f1ca24fbd41188
https://pubmed.ncbi.nlm.nih.gov/28803210
https://pubmed.ncbi.nlm.nih.gov/28803210