Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Geremy Knapp"'
Autor:
Gail M. Nelson, Kirk T. Kitchin, Gene J. Ahlborn, James W. Allen, Hongzu Ren, Bhalchandra A. Diwan, J. Christopher Corton, Geremy Knapp, Don A. Delker, Michael P. Waalkes
Publikováno v:
Toxicology
Exposure of male C3H mice in utero (from gestational days 8–18) to 85 ppm sodium arsenite via the dams’ drinking water has previously been shown to increase liver tumor incidence by 2 years of age. However, in our companion study (Ahlborn et al.,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d6cc82d323ff40e126e0cb8a3987ee3
https://doi.org/10.1016/j.tox.2009.10.004
https://doi.org/10.1016/j.tox.2009.10.004
Autor:
R. Woodrow Setzer, James C Fuscoe, William L. Bigbee, Julia B Scheerer, Liqiang Xi, Geremy Knapp
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 431:291-303
We used a direct polymerase chain reaction (PCR) method for quantification of HPRT exons 2+3 deletions and t(14;18) translocations as a measure of illegitimate V(D)J recombination. We determined the baseline frequencies of these two mutations in mono
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::690d1cee4048931c56f368eeb6c05502
https://doi.org/10.1016/s0027-5107(99)00173-6
https://doi.org/10.1016/s0027-5107(99)00173-6
Publikováno v:
Journal of biochemical and molecular toxicology. 24(3)
In mammals, pyrethroids are neurotoxicants that interfere with ion channel function in excitable neuronal membranes. Previous work demonstrated increases in the expression of Ca(2+)/calmodulin-dependent protein kinase 1-gamma (Camk1g) mRNA following
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::783c8ce85c666daa295266b4e865497c
https://pubmed.ncbi.nlm.nih.gov/20143453
https://pubmed.ncbi.nlm.nih.gov/20143453
Autor:
Kathryn Bailey, Judy L. Mumford, William O. Ward, Jinyao Mo, Russell D. Owen, Geremy Knapp, Yajuan Xia, Sheau-Fung Thai
Publikováno v:
Toxicologic pathology. 37(7)
The skin is an organ that is highly sensitive to chronic arsenic (As) exposure. Skin lesions such as hyperkeratoses (HKs) are common early manifestations of arsenicosis in humans. HKs can be precursor lesions of nonmelanoma skin cancers (NMSCs), but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57842a88767610e1084396be59e2a1f4
https://pubmed.ncbi.nlm.nih.gov/19841129
https://pubmed.ncbi.nlm.nih.gov/19841129
Autor:
William O. Ward, James W. Allen, Thomas G. O'Brien, Geremy Knapp, Yan Chen, Barbara C. Roop, Don A. Delker, Gail M. Nelson, Kirk T. Kitchin, Gene J. Ahlborn, Ming Ouyang
Publikováno v:
Toxicology and applied pharmacology. 227(3)
Chronic drinking water exposure to inorganic arsenic and its metabolites increases tumor frequency in the skin of K6/ODC transgenic mice. To identify potential biomarkers and modes of action for this skin tumorigenicity, we characterized gene express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f584c831577d6f8db51a4b102d0ba52
https://pubmed.ncbi.nlm.nih.gov/18191166
https://pubmed.ncbi.nlm.nih.gov/18191166
Autor:
William O. Ward, Geremy Knapp, Steffen Porwollik, Nancy M. Hanley, Carol D. Swartz, David M. DeMarini, Michael McClelland, Sarah H. Warren
Publikováno v:
Ward, WO; Swartz, CD; Porwollik, S; Warren, SH; Hanley, NM; Knapp, GW; et al.(2007). Toxicogenomic analysis incorporating operon-transcriptional coupling and toxicant concentration-expression response: Analysis of MX-treated Salmonella. BMC Bioinformatics, 8. doi: 10.1186/1471-2105-8-378. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/3cd4f6jp
BMC Bioinformatics, Vol 8, Iss 1, p 378 (2007)
BMC Bioinformatics
BMC Bioinformatics, Vol 8, Iss 1, p 378 (2007)
BMC Bioinformatics
Background Deficiencies in microarray technology cause unwanted variation in the hybridization signal, obscuring the true measurements of intracellular transcript levels. Here we describe a general method that can improve microarray analysis of toxic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60578a925f7dcf2e2df840f0272e5835
Autor:
Geremy Knapp, James C Fuscoe, J T Sandlund, Nancy M. Hanley, Mary V. Relling, C H Pui, R W Setzer
Publikováno v:
Mutation research. 419(1-3)
Etoposide is among the most widely used anti-cancer drugs. Its use, however, has been associated with increased risk of secondary acute myeloid leukemia (AML) which is characterized by chromosomal translocations suggesting involvement of recombinatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f058b13639aca1b806838618207f6db
https://pubmed.ncbi.nlm.nih.gov/9804912
https://pubmed.ncbi.nlm.nih.gov/9804912
Autor:
J. Christopher Corton, Barbara D. Abbott, Geremy Knapp, Hongzu Ren, William O. Ward, Karen J. Ho, Janice S. Lee, Beena Vallanat, Seth J. Karp
Publikováno v:
BMC Genomics
BMC Genomics, Vol 13, Iss 1, p 33 (2012)
BMC Genomics, Vol 13, Iss 1, p 33 (2012)
Background During embryogenesis the liver is derived from endodermal cells lining the digestive tract. These endodermal progenitor cells contribute to forming the parenchyma of a number of organs including the liver and pancreas. Early in organogenes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65ffc80f1ec3a0545acf4cdc1d451eed
https://doi.org/10.1186/1471-2164-13-33
https://doi.org/10.1186/1471-2164-13-33
Publikováno v:
Neurotoxicology and Teratology. 32:504
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7b442b5c278b34a885950bc9b367d63
https://doi.org/10.1016/j.ntt.2010.04.029
https://doi.org/10.1016/j.ntt.2010.04.029
Autor:
Shannahan, J.H.1 (AUTHOR), Ghio, A.J.2 (AUTHOR), Schladweiler, M.C.3 (AUTHOR), Richards, J.H.3 (AUTHOR), Andrews, D.4 (AUTHOR), Gavett, S.H.3 (AUTHOR), Kodavanti, U.P.3 (AUTHOR) kodavanti.urmila@epa.gov
Publikováno v:
Inhalation Toxicology. Jan2012, Vol. 24 Issue 1, p60-69. 10p.