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Akademický článek

Generation of an induced pluripotent stem cell line, JHUi005-A, from a Marfan Syndrome patient harboring a pathogenic c.3338-2A>C intronic splicing variant

Autor: Franklyn D. Hall, III, Christine N. Miller, Sharon Gerecht, Kenneth R. Boheler

Publikováno v: Stem Cell Research, Vol 79, Iss , Pp 103475- (2024)

Marfan Syndrome, a connective tissue disorder caused by Fibrillin-1 (FBN1) gene mutations, induces disease in the ocular, musculoskeletal, and cardiovascular systems and increases aortic vulnerability to rupture associated with high mortality rates.

Externí odkaz: https://doaj.org/article/30bcc2fb1d364247a85bcd16618f551d

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Akademický článek

Deep brain stimulation for the treatment of substance use disorders: a promising approach requiring caution

Autor: Joseph T. Sakai, Jody Tanabe, Sharonya Battula, Morgan Zipperly, Susan K. Mikulich-Gilbertson, Drew S. Kern, John A. Thompson, Kristen Raymond, Pamela David Gerecht, Katrina Foster, Aviva Abosch

Publikováno v: Frontiers in Psychiatry, Vol 15 (2024)

Substance use disorders are prevalent, causing extensive morbidity and mortality worldwide. Evidence-based treatments are of low to moderate effect size. Growth in the neurobiological understanding of addiction (e.g., craving) along with technologica

Externí odkaz: https://doaj.org/article/fc28c5c040df42488d1ea36aa2252179

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Akademický článek

Hydrogels with tunable mechanical plasticity regulate endothelial cell outgrowth in vasculogenesis and angiogenesis

Autor: Zhao Wei, Meng Lei, Yaohui Wang, Yizhou Xie, Xueyong Xie, Dongwei Lan, Yuanbo Jia, Jingyi Liu, Yufei Ma, Bo Cheng, Sharon Gerecht, Feng Xu

Publikováno v: Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)

Abstract The endothelial cell (EC) outgrowth in both vasculogenesis and angiogenesis starts with remodeling surrounding matrix and proceeds with the crosstalk between cells for the multicellular vasculature formation. The mechanical plasticity of mat

Externí odkaz: https://doaj.org/article/7b7130a161d54a99b0bf8bf9a9110e0d

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Akademický článek

Out-of-Hospital Cardiac Arrest

Autor: Gerecht, Ryan B., Nable, Jose V.

Publikováno v: In Cardiology Clinics May 2024 42(2):317-331

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Akademický článek

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Akademický článek

Author Correction: Hydrogels with tunable mechanical plasticity regulate endothelial cell outgrowth in vasculogenesis and angiogenesis

Autor: Zhao Wei, Meng Lei, Yaohui Wang, Yizhou Xie, Xueyong Xie, Dongwei Lan, Yuanbo Jia, Jingyi Liu, Yufei Ma, Bo Cheng, Sharon Gerecht, Feng Xu

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)

Externí odkaz: https://doaj.org/article/59dcaf2133d147f49fa1ba87fe21fd85

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Akademický článek

Out-of-Hospital Cardiac Arrest

Autor: Gerecht, Ryan B., Nable, Jose V.

Publikováno v: In Emergency Medicine Clinics of North America August 2023 41(3):433-453

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Akademický článek

In vitro systems to study endothelial/pericyte cell interactions

Autor: Emily Warren, Sharon Gerecht

Publikováno v: Vascular Biology, Vol 5, Iss 1, Pp 1-11 (2023)

The vasculature is crucial for tissue development and survival, and the stability of blood vessels to perform these functions relies on the interplay between endothelial cells (ECs) and mural cells. Pericytes are a subtype of mural cells found in the

Externí odkaz: https://doaj.org/article/a62c44eda5f4413381a90bcc98fd4db9

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