Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Gerda Szakonyi"'
Autor:
Attila Tököli, Brigitta Bodnár, Ferenc Bogár, Gábor Paragi, Anasztázia Hetényi, Éva Bartus, Edit Wéber, Zsófia Hegedüs, Zoltán Szabó, Gábor Kecskeméti, Gerda Szakonyi, Tamás A. Martinek
Publikováno v:
Pharmaceutics, Vol 15, Iss 4, p 1032 (2023)
Single-stranded DNA-binding protein (SSB) is a bacterial interaction hub and an appealing target for antimicrobial therapy. Understanding the structural adaptation of the disordered SSB C-terminus (SSB-Ct) to DNA metabolizing enzymes (e.g., ExoI and
Externí odkaz:
https://doaj.org/article/171a5d32aa4d46fab92fec3fbf67804e
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47780 (2012)
YjdL from E. coli is an unusual proton-coupled oligopeptide transporter (POT). Unlike prototypical POTs, dipeptides are preferred over tripeptides, in particular dipeptides with a positively charged C-terminal residue. To further understand this diff
Externí odkaz:
https://doaj.org/article/9ca9cb5b0f21476ab58bf47bbb992a88
Publikováno v:
Acta Pharmaceutica Hungarica. 92:20-37
With the increasing development of antibiotic resistance among key bacterial pathogens, there is an urgent need to discover novel classes of antibiotics. Although antimicrobial peptides (AMP) with their specific mode of action are considered major ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de19715e66e2827c6d734c7bdba9500c
https://doi.org/10.33892/aph.2022.92.20-37
https://doi.org/10.33892/aph.2022.92.20-37
Autor:
Edit Wéber, Gerda Szakonyi, Tamás A. Martinek, Beáta Mag, Éva Bartus, László Nyitray, Éva Monostori, Attila Tököli, Ágnes Czibula, Márton A. Simon
Publikováno v:
Chemical Science
The fragment-centric design promises a means to develop complex xenobiotic protein surface mimetics, but it is challenging to find locally biomimetic structures. To address this issue, foldameric local surface mimetic (LSM) libraries were constructed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c96a4aa1f5cd124cd40351b941903b4d
https://pubmed.ncbi.nlm.nih.gov/34094300
https://pubmed.ncbi.nlm.nih.gov/34094300
Publikováno v:
III. Symposium of Young Researchers on Pharmaceutical Technology, Biotechnology and Regulatory Science.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0fc646eedbfb7cba785475ced19f6f72
https://doi.org/10.14232/syrptbrs.2021.op8
https://doi.org/10.14232/syrptbrs.2021.op8
Publikováno v:
III. Fiatal Technológusok Fóruma absztraktfüzet.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f7be961ecedf002380d34a761d2186a
https://doi.org/10.14232/ftf.2020.op10
https://doi.org/10.14232/ftf.2020.op10
Autor:
Joachim Ulrich, Patrick Frohberg, Piroska Szabó-Révész, Zoltán Aigner, Gerda Szakonyi, Tímea Tari, Dániel Madarász, Ildikó Csóka, Rita Ambrus
Publikováno v:
Chemical Engineering & Technology. 40:1323-1331
Additives selectively inhibit or enhance the growth of crystal faces and effectively change crystal morphology. This paper demonstrates the first use of potassium chloride as additive during impinging jet crystallization of glycine, and also describe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::485d4accba5b521b7d607e3b1426c050
https://doi.org/10.1002/ceat.201600634
https://doi.org/10.1002/ceat.201600634
Publikováno v:
I. Symposium of Young Researchers on Pharmaceutical Technology, Biotechnology and Regulatory Science.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ddfcc64f605c29ef4e1cba6d5571ffd
https://doi.org/10.14232/syrptbrs.2019.op10
https://doi.org/10.14232/syrptbrs.2019.op10
Autor:
Katalin Jósvay, Éva Bartus, Zoltán Oláh, Gerda Szakonyi, Lukács Németh, Anasztázia Hetényi, Tamás A. Martinek, Edit Wéber, Zoltán Winter
Publikováno v:
FEBS Letters. 590:2768-2775
There is enormous interest toward vanilloid agonists of the pain receptor TRPV1 in analgesic therapy, but the mechanisms of their sensory neuron-blocking effects at high or repeated doses are still a matter of debate. Our results have demonstrated th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8cfaa4d3f18bf9d3116772ad177ff1b
https://doi.org/10.1002/1873-3468.12267
https://doi.org/10.1002/1873-3468.12267
Publikováno v:
ChemistryOpen
Protein–protein interactions stabilized by multiple separate hot spots are highly challenging targets for synthetic scaffolds. Surface‐mimetic foldamers bearing multiple recognition segments are promising candidate inhibitors. In this work, a mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ead77cdfd7fd1fa0ce57aab93d837aa1
https://pubmed.ncbi.nlm.nih.gov/28413758
https://pubmed.ncbi.nlm.nih.gov/28413758