Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Gerd Woehrle"'
Autor:
Samuel O. Kyeremateng, Sergei G. Kazarian, James A. Kimber, Leonardo A.M. Williams, Gerd Woehrle, Holger van Lishaut, Marieke Pudlas
Publikováno v:
European Journal of Pharmaceutical Sciences
The drug release performance of hot-melt extrudate formulations is mainly affected by its composition and interactions between excipients, drug and the dissolution media. For targeted formulation development, it is crucial to understand the role of t
Autor:
Sebastian H. Dreis-Kühne, Samuel O. Kyeremateng, Frank Theil, Gerd Woehrle, Holger van Lishaut, Jörg Rosenberg, Markus Mägerlein, Sankaran Anantharaman
Publikováno v:
Molecular pharmaceutics. 14(1)
Kinetically stabilized amorphous solid dispersions are inherently metastable systems. Therefore, such systems are generally considered prone to recrystallization. In some cases, the formation of crystals will impact the bioavailability of the active
Publikováno v:
Journal of pharmaceutical sciences. 103(9)
A novel empirical analytical approach for estimating solubility of crystalline drugs in polymers has been developed. The approach utilizes a combination of differential scanning calorimetry measurements and a reliable mathematical algorithm to constr