Zobrazeno 1 - 10
of 567
pro vyhledávání: '"Gerd Ulrich"'
Autor:
Jingzhe Guo, Wilhelmina T Van De Ven, Aleksandra Skirycz, Venkatesh P. Thirumalaikumar, Liping Zeng, Quanqing Zhang, Gerd Ulrich Balcke, Alain Tissier, Katayoon Dehesh
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Methylerythritol cyclodiphosphate (MEcPP) is an intermediate in the biosynthesis of isoprenoids in plant plastids and in bacteria, and acts as a stress signal in plants. Here, we show that MEcPP regulates biofilm formation in Escherichia col
Externí odkaz:
https://doaj.org/article/e2c1cd53eb3346aaa868c94c7d503e6b
Autor:
Martin Štefl, Masanari Takamiya, Volker Middel, Miyase Tekpınar, Karin Nienhaus, Tanja Beil, Sepand Rastegar, Uwe Strähle, Gerd Ulrich Nienhaus
Publikováno v:
iScience, Vol 27, Iss 2, Pp 108849- (2024)
Summary: Repair of lesions in the plasma membrane is key to sustaining cellular homeostasis. Cells maintain cytoplasmic as well as membrane-bound stores of repair proteins that can rapidly precipitate at the site of membrane lesions. However, little
Externí odkaz:
https://doaj.org/article/b4511a54e95f4dbc9f67e39a510c4315
Autor:
Manuel Hüpfel, Gerd Ulrich Nienhaus
Publikováno v:
JPhys Photonics, Vol 6, Iss 3, p 035003 (2024)
Thanks to its unique optical sectioning capability, light-sheet fluorescence microscopy has proven to be a powerful technique for volumetric imaging of entire model organisms with high spatial and temporal resolution. For light sheet generation with
Externí odkaz:
https://doaj.org/article/35c2ef1b5f5548bba1e8d598ed4f0251
Autor:
Agnieszka Pancholi, Tim Klingberg, Weichun Zhang, Roshan Prizak, Irina Mamontova, Amra Noa, Marcel Sobucki, Andrei Yu Kobitski, Gerd Ulrich Nienhaus, Vasily Zaburdaev, Lennart Hilbert
Publikováno v:
Molecular Systems Biology, Vol 17, Iss 9, Pp 1-26 (2021)
Abstract It is essential for cells to control which genes are transcribed into RNA. In eukaryotes, two major control points are recruitment of RNA polymerase II (Pol II) into a paused state, and subsequent pause release toward transcription. Pol II r
Externí odkaz:
https://doaj.org/article/e2cf57e85b014bc6b986a21ecfb1a26b
Autor:
Katharina Puzik, Veronika Tonnier, Isabell Opper, Antonia Eckert, Lu Zhou, Marie-Claire Kratzer, Ferdinand le Noble, Gerd Ulrich Nienhaus, Dietmar Gradl
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
Abstract The activation of distinct branches of the Wnt signaling network is essential for regulating early vertebrate development. Activation of the canonical Wnt/β-catenin pathway stimulates expression of β-catenin-Lef/Tcf regulated Wnt target ge
Externí odkaz:
https://doaj.org/article/5d0d6020b0a44fca92dd365bddb89771
Autor:
Meltem Weger, Benjamin D Weger, Andrea Schink, Masanari Takamiya, Johannes Stegmaier, Cédric Gobet, Alice Parisi, Andrei Yu Kobitski, Jonas Mertes, Nils Krone, Uwe Strähle, Gerd Ulrich Nienhaus, Ralf Mikut, Frédéric Gachon, Philipp Gut, Thomas Dickmeis
Publikováno v:
eLife, Vol 9 (2020)
The glucose-sensing Mondo pathway regulates expression of metabolic genes in mammals. Here, we characterized its function in the zebrafish and revealed an unexpected role of this pathway in vertebrate embryonic development. We showed that knockdown o
Externí odkaz:
https://doaj.org/article/3ce0c8c614c1482a8e39f6ec82430ce8
Autor:
Masanari Takamiya, Johannes Stegmaier, Andrei Yu Kobitski, Benjamin Schott, Benjamin D Weger, Dimitra Margariti, Angel R Cereceda Delgado, Victor Gourain, Tim Scherr, Lixin Yang, Sebastian Sorge, Jens C Otte, Volker Hartmann, Jos van Wezel, Rainer Stotzka, Thomas Reinhard, Günther Schlunck, Thomas Dickmeis, Sepand Rastegar, Ralf Mikut, Gerd Ulrich Nienhaus, Uwe Strähle
Publikováno v:
PLoS Genetics, Vol 16, Iss 6, p e1008774 (2020)
Cranial neural crest (NC) contributes to the developing vertebrate eye. By multidimensional, quantitative imaging, we traced the origin of the ocular NC cells to two distinct NC populations that differ in the maintenance of sox10 expression, Wnt sign
Externí odkaz:
https://doaj.org/article/8e4da45e746442678c656ac1c39e9a74
Autor:
Antonia Franziska Eckert, Peng Gao, Janine Wesslowski, Xianxian Wang, Jasmijn Rath, Karin Nienhaus, Gary Davidson, Gerd Ulrich Nienhaus
Publikováno v:
eLife, Vol 9 (2020)
Development and homeostasis of multicellular organisms is largely controlled by complex cell-cell signaling networks that rely on specific binding of secreted ligands to cell surface receptors. The Wnt signaling network, as an example, involves multi
Externí odkaz:
https://doaj.org/article/eda06825faa94ae3b299d7bc550f4be1
Autor:
Thomas Kowoll, Susanne Fritsch-Decker, Silvia Diabaté, Gerd Ulrich Nienhaus, Dagmar Gerthsen, Carsten Weiss
Publikováno v:
Journal of Nanobiotechnology, Vol 16, Iss 1, Pp 1-15 (2018)
Abstract Background Particokinetic models are important to predict the effective cellular dose, which is key to understanding the interactions of particles with biological systems. For the reliable establishment of dose–response curves in, e.g., th
Externí odkaz:
https://doaj.org/article/d8f854b784224db883c980cd9d97daeb
Autor:
Ulschan Scheler, Wolfgang Brandt, Andrea Porzel, Kathleen Rothe, David Manzano, Dragana Božić, Dimitra Papaefthimiou, Gerd Ulrich Balcke, Anja Henning, Swanhild Lohse, Sylvestre Marillonnet, Angelos K. Kanellis, Albert Ferrer, Alain Tissier
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Diterpenes are plant products with high antioxidant properties and potential application as food additives and therapeutics. Here, the authors describe the complete biosynthetic pathway of carnosic acid and reconstruct it in yeast, opening the way to
Externí odkaz:
https://doaj.org/article/eae7c8f3c7ec41be8b6d83b1c48ac17f