Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Gerd Schreurs"'
Autor:
Gerd Schreurs, Stuart Maudsley, Cynthia Nast, Marleen Praet, Sylvina Da Silva Fernandes, Peter Boor, Patrick D’Haese, Marc E. De Broe, Benjamin A. Vervaet
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract CINAC-patients present renal proximal tubular cell lysosomal lesions which are also observed in patients experiencing calcineurin inhibitor (CNI) nephrotoxicity, suggesting that CINAC is a toxin-induced nephropathy. An alternative hypothesis
Externí odkaz:
https://doaj.org/article/6be3755f172742d2a584a36cadf387ba
Autor:
Cynthia C. Nast, Channa Jayasumana, Nika Kojc, Gerd Schreurs, Marc E. De Broe, Chula Herath, Benjamin A. Vervaet
Publikováno v:
Néphrologie & thérapeutique
Chronic interstitial nephritis in agricultural communities is a devastating kidney disease with a globally increasing prevalence. Its cause is unknown. Two predominant etiologies are hypothesised: recurrent episodes of dehydration and exposure to env
Autor:
Walter E. Cabrera J, Benjamin A. Vervaet, Gerd Schreurs, Cynthia C. Nast, Francisco Santa-Cruz, Marc E. De Broe
Publikováno v:
Kidney International Reports
Autor:
Marc E. De Broe, Vahid Samaee, Frank Roels, Channa Jayasumana, Rajeewa Dassanayake, Vincent Vuiblet, Benjamin A. Vervaet, Swarnalata Gowrishankar, Christiane Mousson, Sonali Rodrigo, Claire Rigothier, Patrick C. D'Haese, Cynthia C. Nast, Carlos M. Orantes, Chula Herath, Nika Kojc, Gerd Schreurs
Publikováno v:
Kidney international
Almost 30 years after the detection of chronic interstitial nephritis in agricultural communities (CINAC) its etiology remains unknown. To help define this we examined 34 renal biopsies from Sri Lanka, El Salvador, India and France of patients with c
Autor:
Channa Jayasumana, Chula Herath, Gerd Schreurs, Marc E. De Broe, Cynthia C. Nast, Benjamin A. Vervaet
Publikováno v:
Kidney International. 98:787-789
Autor:
Annelies Breynaert, Laura Peeters, Anja Verhulst, Nina Hermans, Kenn Foubert, Luc Pieters, Gerd Schreurs
Publikováno v:
Journal of ethnopharmacology
Ethnopharmacological relevance: Herniaria hirsuta is traditionally used in Moroccan folk medicine for treatment of urinary stones and as a diuretic. It is rich in saponins, which are known to be deglycosylated in the colon, whereafter aglycones such
Autor:
Gerd Schreurs, Nika Kojc, Swarnalata Gowrishankar, Vincent Vuiblet, Claire Rigothier, Patrick C. D'Haese, Rajeewa Dassanayake, Marc E. De Broe, Sonali Rodrigo, Christiane Mousson, Vahid Samaee, Chula Herath, Carlos M. Orantes, Cynthia C. Nast, Benjamin A. Vervaet, Frank Roels, Channa Jayasumana
Publikováno v:
Nephrology Dialysis Transplantation. 35
Background and Aims In CINAC patients from Sri Lanka, we recently observed a sensitive constellation of proximal tubular cell findings including cellular/tubular atrophy, cell fragment shedding and, by electron microscopy (EM), the presence of an inc
Autor:
Marc E. De Broe, Benjamin A. Vervaet, Patrick C. D'Haese, Gerd Schreurs, Cynthia C. Nast, Nika Kojc
Publikováno v:
Nephrology Dialysis Transplantation. 35
Background and Aims Calcineurin inhibitor therapy has changed the field of (renal) transplantation by considerably prolonging graft survival. Yet, all immunosuppressive calcineurin inhibitors are nephrotoxic that eventually contribute to complete sca
Autor:
Gerd Schreurs, Patrick C. D'Haese, Cynthia C. Nast, Marc E. De Broe, Benjamin A. Vervaet, Stuart Maudsley
Publikováno v:
Nephrology Dialysis Transplantation. 35
Background and Aims CINAC patients present a newly discovered constellation of proximal tubular lysosomal lesions which is also observed in patients experiencing calcineurin inhibitor (CNI) nephrotoxicity, suggesting that CINAC is a toxin-induced nep
Autor:
Frank Roels, Patrick C. D'Haese, Sonali Rodrigo, Carlos M. Orantes, Claire Rigothier, Gerd Schreurs, Channa Jayasumana, Vincent Vuiblet, Vahid Samaee, Nika Kojc, Rajeewa Dassanayake, Cynthia C. Nast, Chula Herath, Benjamin A. Vervaet, Christiane Mousson, Swarnalata Gowrishankar, Marc E. De Broe
Publikováno v:
Nephrology Dialysis Transplantation. 35
Background and Aims 30 years after the detection of CINAC, there is no consensus on its etiology. Heat stress/dehydration and toxic exposure are the two most likely etiologies. There are no diagnostic criteria that can directly identify CINAC patient