Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Gerd Osswald"'
Autor:
J. L. Ives, Bronk Brian Scott, Gerd Osswald, Wesley F. Austin, Nathan O. Fuller, Jed L. Hubbs, Ruichao Shen
Publikováno v:
Organic Process Research & Development. 18:683-692
This work describes the demonstration of a kilogram-scale synthesis of a γ-secretase modulator from a plant-sterol-derived starting material. Key to developing a synthetic route capable of delivering a kilogram of the target compound was the develop
Autor:
Dieter Haag, Mark A. Findeis, Wesley F. Austin, Nathan O. Fuller, Janos Kovacs, Ruichao Shen, Steffen Phillip Creaser, Gerd Osswald, Jed L. Hubbs, J. L. Ives, Bronk Brian Scott
Publikováno v:
Organic Process Research & Development. 18:676-682
The process development and production of two cycloartenol triterpenoid glycosides on a multikilogram scale are described. The two compounds were used as key intermediates for the synthesis of a γ-secretase modulator and a novel potential therapeuti