Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Gerd Mittelstädt"'
Autor:
Christin Radon, Gerd Mittelstädt, Benjamin R. Duffus, Jörg Bürger, Tobias Hartmann, Thorsten Mielke, Christian Teutloff, Silke Leimkühler, Petra Wendler
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Rhodobacter capsulatus NAD+ dependent formate dehydrogenase (RcFDH) is a molybdoenzyme that catalyses the reversible oxidation of formate to carbon dioxide, and is of interest for biotechnological applications. Here the authors present the cryo-EM st
Externí odkaz:
https://doaj.org/article/ee6fb5dae1e445018b0579d644893722
Publikováno v:
Biochemistry. 61:1883-1893
Enzyme-catalyzed hydrolysis is a fundamental chemical transformation involved in many essential metabolic processes. The enzyme 5'-methylthioadenosine/
Publikováno v:
Philosophical Transactions of the Royal Society B: Biological Sciences. 378
Anthranilate phosphoribosyltransferase catalyses the second reaction in the biosynthesis of tryptophan from chorismate in microorganisms and plants. The enzyme is homodimeric with the active site located in the hinge region between two domains. A ran
Autor:
Isabelle Montgomerie, Thomas W. Bird, Olga R. Palmer, Ngarangi C. Mason, Theresa E. Pankhurst, Blair Lawley, Leonor C. Hernández, Rhodri Harfoot, Astrid Authier-Hall, Danielle E. Anderson, Kerry L. Hilligan, Kaitlin H. Buick, Naasson M. Mbenza, Gerd Mittelstädt, Samara Maxwell, Shubhra Sinha, Joanna Kuang, Kanta Subbarao, Emily J. Parker, Alan Sher, Ian F. Hermans, James E. Ussher, Miguel E. Quiñones-Mateu, Davide Comoletti, Lisa M. Connor
Publikováno v:
iScience. 26:106256
Autor:
Isabelle Stewart, Thomas W. Bird, Olga Rose Palmer, Ngarangi Claire Mason, Theresa Ellen Pankhurst, Blair Lawley, Leonor C. Hernández, Rhodri Harfoot, Astrid Authier-Hall, Kerry L. Hilligan, Kaitlin Buick, Naasson M. Mbenza, Gerd Mittelstädt, Samara Maxwell, Shubra Sinha, Joanna Kuang, Emily Parker, Alan Sher, Ian F. Hermans, James Ussher, Miguel E. Quiñones-Mateu, Davide Comoletti, Lisa M Connor, VAANZ Group
Publikováno v:
SSRN Electronic Journal.
Autor:
Silke Leimkühler, Petra Wendler, Benjamin R. Duffus, Jörg Bürger, Thorsten Mielke, Tobias Hartmann, Christian Teutloff, Christin Radon, Gerd Mittelstädt
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Metal-containing formate dehydrogenases (FDH) catalyse the reversible oxidation of formate to carbon dioxide at their molybdenum or tungsten active site. They display a diverse subunit and cofactor composition, but structural information on these enz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2b62ab6f961453be82b899d84cabd69
https://hdl.handle.net/21.11116/0000-0006-4E44-721.11116/0000-0006-4E46-5
https://hdl.handle.net/21.11116/0000-0006-4E44-721.11116/0000-0006-4E46-5
Autor:
Gerd Mittelstädt, Emma K. Livingstone, Wanting Jiao, Emily J. Parker, Gert-Jan Moggré, Ali Reza Nazmi
Publikováno v:
Biochemical Journal. 475:247-260
Adenosine triphosphate (ATP) phosphoribosyltransferase (ATP-PRT) catalyses the first committed step of histidine biosynthesis in plants and microorganisms. Two forms of ATP-PRT have been reported, which differ in their molecular architecture and mech
Hinge Twists and Population Shifts Deliver Regulated Catalysis for ATP-PRT in Histidine Biosynthesis
Publikováno v:
Biophys J
Allosteric regulation plays an important role in the control of metabolic flux in biosynthetic pathways. In microorganisms, many enzymes in these pathways adopt different strategies of allostery to allow the tuning of their activities in response to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e784395c32aa2368f7303dd3458c502
https://europepmc.org/articles/PMC6531924/
https://europepmc.org/articles/PMC6531924/
Publikováno v:
FEBS Letters. 590:2603-2610
ATP-phosphoribosyltransferase (ATP-PRT) catalyses the first step of histidine biosynthesis. Two different forms of ATP-PRT have been described; the homo-hexameric long form, and the hetero-octameric short form. Lactococcus lactis possesses the short
Publikováno v:
Protein Science. 25:1492-1506
Adenosine triphosphate phosphoribosyltransferase (ATP-PRT) catalyzes the first committed step of the histidine biosynthesis in plants and microorganisms. Here, we present the functional and structural characterization of the ATP-PRT from the pathogen