Zobrazeno 1 - 10 of 143 pro vyhledávání: '"Gerd Kobal"'
1
The roles of TRPV1, TRPA1 and TRPM8 channels in chemical and thermal sensitivity of the mouse oral mucosa
Autor: Winfried Neuhuber, Tatjana I. Kichko, Gerd Kobal, Peter W. Reeh
Publikováno v: European Journal of Neuroscience. 47:201-210
Spices in food and beverages and compounds in tobacco smoke interact with sensory irritant receptors of the transient receptor potential (TRP) cation channel family. TRPV1 (vanilloid type 1), TRPA1 (ankyrin 1) and TRPM8 (melastatin 8) not only elicit
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00ccc0925e26ecf6c60a5b62b312095e
https://doi.org/10.1111/ejn.13799
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2
Chemo-somatosensory evoked potentials
Autor: Bertold Renner, Gerd Kobal, Miriam Kunz, Stefan Lautenbacher, Stephan Roscher, Parvaneh Mohammadian
Publikováno v: Somatosensory & Motor Research, 31(2), 100-10. Taylor & Francis Ltd
UNLABELLED: Abstract Background: Chemo-somatosensory evoked potentials (CSSEPs) elicited by chemical stimulation (CO₂ gas) of the nasal mucosa have been shown to be sensitive enough to pick up even weak analgesic effects. With the present study we
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b51a1bde6180335525ec093656f8e06e
https://hdl.handle.net/11370/ca0d23be-c909-48c5-8b04-32415e5c1d2d
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3
Tonic stimulation of the pharyngeal mucosa causes pain and a reversible increase of inflammatory mediators
Autor: Bertold Renner, Gabi Ahne, Gerd Kobal, Adrian Shephard, Birgit Kettenmann, Elke Grosan
Publikováno v: Inflammation Research
Objective and design To develop a model of the inflammatory component of non-infectious sore throat using tonic stimulation and quantification of inflammatory mediators in pharyngeal lavage fluid. Material or subjects Forty-five healthy volunteers. T
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e3bcf43d651b7c6232d4abeb83637fb
https://doi.org/10.1007/s00011-013-0663-7
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4
Bimodal Concentration-Response of Nicotine Involves the Nicotinic Acetylcholine Receptor, Transient Receptor Potential Vanilloid Type 1, and Transient Receptor Potential Ankyrin 1 Channels in Mouse Trachea and Sensory Neurons
Autor: Gerd Kobal, Tatjana I. Kichko, Mirjam Eberhardt, Peter W. Reeh, Winfried Neuhuber, Jochen K. Lennerz, Ramona Madalina Babes
Publikováno v: Journal of Pharmacology and Experimental Therapeutics. 347:529-539
High concentrations of nicotine, as in the saliva of oral tobacco consumers or in smoking cessation aids, have been shown to sensitize/activate recombinant transient receptor potential vanilloid type 1 (rTRPV1) and mouse TRPA1 (mTRPA1) channels. By m
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99b5cf3bbadb4677d91d728085a5ebf4
https://doi.org/10.1124/jpet.113.205971
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5
Evaluation of the Effect of Ammonia on Nicotine Pharmacokinetics Using Rapid Arterial Sampling
Autor: William H. Barr, Gerd Kobal, Kelly Fisher, Diana Mckinney, W. Hans Carter, Maria Gogova, Viswanathan Ramakrishnan, Bruce D. Davies, William R. Garnett, Sunil S. Iyer, H. Thomas Karnes, Amit A. Somani
Publikováno v: Nicotine & Tobacco Research. 14:586-595
INTRODUCTION: The nicotine bolus theory states that the dependence-producing potential of cigarettes relates to a rapid increase in nicotine at brain receptor sites. It has been suggested that ammonia, a compound typically found in tobacco products,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1dc3a03e65a0140f8434e3596c448dc
https://doi.org/10.1093/ntr/ntr257
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6
The Candy Smell Test in Clinical Routine
Autor: Andreas Faldum, Stephan Letzel, Bertold Renner, Shannon Bertz-Duffy, Gerd Kobal, Bernhard Stein, Sokrates Trellakis, Boris R. Haxel, Axel Muttray, Wolf J. Mann
Publikováno v: American Journal of Rhinology & Allergy. 25:e145-e148
Background The “Candy Smell Test” (CST) has been introduced as a new testing method for the evaluation of the human sense of smell. In contrast to other established orthonasal smell tests, the CST addresses the retronasal application of odors, ty
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ec84e4dea7ced9aaae31b48d5d96fc5
https://doi.org/10.2500/ajra.2011.25.3611
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7
Rapid automated blood sampling system for pharmacokinetics studies of cigarette smoking
Autor: William M. Adams, Diana Mckinney, William H. Barr, William R. Garnett, Sunil S. Iyer, Maria Gogova, Gerd Kobal, H. Thomas Karnes, Wayne Lewis, Chad Powell, Bruce D. Davies
Publikováno v: Nicotine & Tobacco Research. 12:319-325
Introduction We developed an automated sampling system to allow multiple, discrete blood samples from a human participant to be collected rapidly and immediately following cigarette smoke exposure. We reported the details of the sampling system along
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e7c63a55a2ffbdf84d9b5add482d4d1
https://doi.org/10.1093/ntr/ntp190
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8
Effect of Nicotine on Chorda Tympani Responses to Salty and Sour Stimuli
Autor: Vijay Lyall, Tam-Hao T. Phan, Gerd Kobal, John A. DeSimone, Shobha Mummalaneni, Mahdis Mansouri, Gerard L. Heck
Publikováno v: Journal of Neurophysiology. 98:1662-1674
The effect of nicotine on the benzamil (Bz)-insensitive (transient receptor potential vanilloid-1 variant cation channel, TRPV1t) and the Bz-sensitive (epithelial Na+ channel, ENaC) salt taste receptors and sour taste was investigated by monitoring i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3872a235c17800792e2dd3e50b14a8ea
https://doi.org/10.1152/jn.00366.2007
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9
Normative data for the 'Sniffin’ Sticks' including tests of odor identification, odor discrimination, and olfactory thresholds: an upgrade based on a group of more than 3,000 subjects
Autor: Alan Mackay-Sim, Hilmar Gudziol, Gerd Kobal, Thomas Hummel
Publikováno v: European Archives of Oto-Rhino-Laryngology. 264:237-243
"Sniffin' Sticks" is a test of nasal chemosensory function that is based on pen-like odor dispensing devices, introduced some 10 years ago by Kobal and co-workers. It consists of tests for odor threshold, discrimination, and identification. Previous
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::694f9d5cd347986318b547b0e09a6c95
https://doi.org/10.1007/s00405-006-0173-0
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10
Electro-olfactograms are present when odorous stimuli have not been perceived
Autor: Jos Mojet, Thomas Hummel, Gerd Kobal
Publikováno v: Neuroscience Letters, 397(3), 224-228
Neuroscience Letters 397 (2006) 3
76. Jahresversammlung der Deutschen Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf-und Hals-Chirurgie e.V.; 20050504-20050508; Erfurt; DOC05hno479 /20050922/
After chemical stimulation of the human olfactory epithelium it is possible to record a negative response (electro-olfactogram, EOG) which is interpreted as the summated generator potential of olfactory neurons. The aim of the present investigation w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f7c360275215db08c2b48089ef31868
https://doi.org/10.1016/j.neulet.2005.12.048
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