Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Gerd Kager"'
Autor:
Christine Rossmann, Cornelia Ranz, Gerd Kager, Gerhard Ledinski, Martin Koestenberger, Willibald Wonisch, Thomas Wagner, Sebastian P. Schwaminger, Bruno Di Geronimo, Andelko Hrzenjak, Seth Hallstöm, Gilbert Reibnegger, Gerhard Cvirn, Margret Paar
Publikováno v:
Pharmaceutics, Vol 15, Iss 8, p 2111 (2023)
Metformin is the most commonly prescribed glucose-lowering drug for the treatment of type 2 diabetes. The aim of this study was to investigate whether metformin is capable of impeding the oxidation of LDL, a crucial step in the development of endothe
Externí odkaz:
https://doaj.org/article/9bbf4f263d38442cb03d53efcf102673
Autor:
Shalett Mathew, Ouafa Hamza, Bruno K. Podesser, Eylem Acar, Attila Kiss, Christopher Dostal, Simon Watzinger, Petra L. Szabo, Gerd Kager, Seth Hallström, Patrick M. Pilz
Publikováno v:
Journal of Cardiovascular Pharmacology and Therapeutics
Background: Vascular stiffness and endothelial dysfunction are accelerated by acute myocardial infarction (AMI) and subsequently increase the risk for recurrent coronary events. Aim: To explore whether remote ischemic perconditioning (RIPerc) protect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23468c1dbbcfde381a00a5ccedc11c6b
https://doi.org/10.1177/10742484211031327
https://doi.org/10.1177/10742484211031327
Autor:
Karl H. Schneider, Christian Grasl, Seth Hallström, Heinrich Schima, Marjan Enayati, Johann Wojta, Lubos Budinsky, Beat H. Walpoth, Barbara Messner, Gerd Kager, Bruno K. Podesser, Ingrid Walter, Christoph Kaun, Ciarra Almeria, Sabrina Rohringer, Helga Bergmeister
Publikováno v:
Acta biomaterialia. 134
Currently available synthetic small diameter vascular grafts reveal low patency rates due to thrombosis and intimal hyperplasia. Biofunctionalized grafts releasing nitric oxide (NO) in situ may overcome these limitations. In this study, a drug-elutin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0671ea90f6b0b609929309867827de2e
https://pubmed.ncbi.nlm.nih.gov/34329787
https://pubmed.ncbi.nlm.nih.gov/34329787
Autor:
Guenther Juergens, Gerhard Cvirn, Thomas Gary, Martin Koestenberger, Gerhard Ledinski, Gerd Hoerl, Michael Thalhammer, Gerd Kager
Publikováno v:
Chemistry and Physics of Lipids. 184:38-41
Plaque formation is confined to the arterial trunk. We assumed that due to the higher aeration of arterial compared to venous blood, higher levels of the atherogenic agent oxidized LDL might be present in arteries, contributing to plaque formation. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bba558caf64b162c8155e6aac9d50d53
https://doi.org/10.1016/j.chemphyslip.2014.09.004
https://doi.org/10.1016/j.chemphyslip.2014.09.004
Autor:
Gerhard Cvirn, Gerd Kager, Günther Jürgens, Gerhard Ledinski, Erwin Tafeit, Gerd Hörl, Seth Hallström, Martin Koestenberger
Publikováno v:
Chemistry and physics of lipids. 183
Recent studies suggest that ozone is present in atherosclerotic lesions. Since these lesions are characterized by a dramatic accumulation of low-density lipoprotein (LDL), we aimed to investigate whether ozone is capable of oxidizing LDL, thereby ren
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fca2b3e9700ab6361ce7ceb4218d7d52
https://pubmed.ncbi.nlm.nih.gov/24835738
https://pubmed.ncbi.nlm.nih.gov/24835738
Publikováno v:
Journal of Cellular Biochemistry. 81:557-569
Oxidatively modified low-density lipoprotein (LDL) has been found in vivo, and oxidized LDL (oxLDL) could bind to scavenger receptors, leading to foam cell formation. Macrophages bear a number of different scavenger receptors for oxLDL, and macrophag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68f1420072a603454132470bd1689457
https://doi.org/10.1002/1097-4644(20010601)81:3<557::aid-jcb1069>3.0.co
https://doi.org/10.1002/1097-4644(20010601)81:3<557::aid-jcb1069>3.0.co
Autor:
Judith S. Fabjan, Astrid Burda, H. P. Hofer, Ernst Pilger, Andrea Obernosterer, Günther Jürgens, G. Egger, Gerd Kager, Heike Mitterhammer
Publikováno v:
Inflammation. 25:129-135
The aim of the study was to demonstrate an activation of polymorpho-nuclear leukocytes (PMNs) in chronic progressive atherosclerosis (ATH). A group of patients with ATH, and a group of ATH patients under aspirin (ASA) therapy were compared with contr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57b4c271d737978ff809bff01872156d
https://doi.org/10.1023/a:1007174723608
https://doi.org/10.1023/a:1007174723608
Autor:
Gerhard Ledinski, Günther Jürgens, Darko Cerne, Gerd Kager, Joachim Greilberger, Xiasong Wang
Publikováno v:
cclm. 38:529-538
We compared several “new” risk factors (autoantibodies to oxidatively modified low density lipoprotein (LDL), sialic acid content of LDL, bilirubin and C-reactive protein) with “conventional” risk factors (apolipoprotein (apo) AI, AII and B,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9975c98734056494d9f4acd5cdb72cda
https://doi.org/10.1515/cclm.2000.078
https://doi.org/10.1515/cclm.2000.078
Autor:
Joachim Greilberger, Günther Jürgens, Xiaosong Wang, Gerhard Ledinski, Gerd Kager, Beverly Paigen
Publikováno v:
Atherosclerosis. 172(2)
There is accumulating evidence that LDL oxidation is essential for atherogenesis, and that antioxidants that prevent this oxidation may either slow down or prevent atherogenesis. In the present study, we found that Commiphora mukul and its cholestero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c2ee3bf2373f30dac226d8efc226eef
https://pubmed.ncbi.nlm.nih.gov/15019533
https://pubmed.ncbi.nlm.nih.gov/15019533
Autor:
Günther Jürgens, Jana Lukac-Bajalo, Darko Cerne, Joachim Greilberger, Gerd Kager, Gerhard Ledinski
Publikováno v:
Clinical Chemistry and Laboratory Medicine. 40
To determine whether the sialic acid (SA) content of the low-density lipoprotein (LDL) is related to the plasma concentration of autoantibodies to oxidized LDL (oxLDL), we measured the SA content of LDL and the concentrations of oxLDL and autoantibod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3def49a9eb4e6a0d869cdaa60e16398
https://doi.org/10.1515/cclm.2002.004
https://doi.org/10.1515/cclm.2002.004