Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Gerd Heimlich"'
Autor:
Gerd Heimlich, John A. Cidlowski
Publikováno v:
Journal of Biological Chemistry. 281:2232-2241
Apoptosis is a genetic program for the removal of unwanted cells from an organism, which is distinct from necrosis by its characteristic volume loss or apoptotic volume decrease. This cell shrinkage is the result of ion redistribution that is crucial
Autor:
Gerd Heimlich, Karin Roberg, Ann-Charlotte Johansson, Nancy Wang, Uno Johansson, Juliane M. Jürgensmeier, Karin Öllinger, Katarina Kågedal
Publikováno v:
International Journal of Experimental Pathology. 86:309-321
Bcl-2 family members have long been known to control permeabilization of the mitochondrial membrane during apoptosis, but involvement of these proteins in lysosomal membrane permeabilization (LMP) was not considered until recently. The aim of this st
Autor:
Alastair D. McKinnon, Juliane M. Jürgensmeier, Katussevani Bernardo, Martin Krönke, Gerd Heimlich, Dieter Brdiczka, Renate Kain, John C. Reed
Publikováno v:
Biochemical Journal. 378:247-255
The pro-apoptotic protein Bax plays a key role in the mitochondrial signalling pathway. Upon induction of apoptosis, Bax undergoes a conformational change and translocates to mitochondrial membranes, where it inserts and mediates the release of cytoc
Autor:
Dieter Brdiczka, Gerd Heimlich, Ljubava D. Zorova, Dmitry B. Zorov, Juliane M. Jürgensmeier, Dietmar Schreiner, Michail Vyssokikh
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1644:27-36
The mechanism of Bax-dependent cytochrome c release is still controversial and may also depend on the actual localisation of cytochrome C: (i) we studied the distribution of cytochrome c in sub-fractions of rat kidney mitochondria and found that 10-2
Autor:
Gerd Heimlich, Dieter Brdiczka, Dmitry B. Zorov, Juliane M. Jürgensmeier, Mikhail Yu. Vyssokikh, Ljubava D. Zorova
Publikováno v:
Molecular Biology Reports. 29:93-96
The mechanism by which external Bax releases cytochrome c is still controversial and may also depend on the type of mitochondria and the actual localisation of cytochrome c. Outer membrane porin acquires high binding affinity for hexokinase by intera
Publikováno v:
Journal of the American Chemical Society. 122:4742-4749
The electron-transfer rate constants for oligonucleotides containing adjacent guanines were determined by digital simulation of cyclic voltammograms of Ru(bpy)32+ in the presence of the oligonucleotides (bpy = 2,2‘-bipyridine). These experiments sh
Publikováno v:
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 12(6)
AIMS: Cardiac resynchronization therapy (CRT) is the standard treatment for heart failure with severe reduced left ventricular (LV) function and wide QRS complex. Coronary sinus (CS) lead implantation is challenging and accompanied by substantial dis
Publikováno v:
Advances in experimental medicine and biology. 559
Publikováno v:
Cell Volume and Signaling ISBN: 9780387232997
The understanding of programmed cell death or apoptosis has become one of the most studied and fastest growing fields in the life science area. The implication of volume regulatory mechanisms, ion channels as well as ion movements, are recognized as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88390b9fc9e5e07fbef02b680c9b0554
https://doi.org/10.1007/0-387-23752-6_18
https://doi.org/10.1007/0-387-23752-6_18
Autor:
Hinrich Abken, Gerd Heimlich, Anke Deggerich, Benjamin Yazdanpanah, Jens Michael Seeger, Hamid Kashkar, M Krönke, Andreas Hombach, Olaf Utermohlen
Publikováno v:
Blood. 108(10)
The immunosurveillance of Hodgkin lymphoma (HL) by cytotoxic T lymphocytes (CTLs) is insufficient, and the clinical experience with adoptive transfer of CTLs is limited. We have previously reported that defects in mitochondrial apoptotic pathways and