Zobrazeno 1 - 10
of 233
pro vyhledávání: '"Gerd, Sutter"'
Autor:
Yiqi Huang, Valter Bergant, Vincent Grass, Quirin Emslander, M. Sabri Hamad, Philipp Hubel, Julia Mergner, Antonio Piras, Karsten Krey, Alexander Henrici, Rupert Öllinger, Yonas M. Tesfamariam, Ilaria Dalla Rosa, Till Bunse, Gerd Sutter, Gregor Ebert, Florian I. Schmidt, Michael Way, Roland Rad, Andrew G. Bowie, Ulrike Protzer, Andreas Pichlmair
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Multiple omics analyzes of Vaccinia virus (VACV) infection have defined molecular characteristics of poxvirus biology. However, little is known about the monkeypox (mpox) virus (MPXV) in humans, which has a different disease manifestation de
Externí odkaz:
https://doaj.org/article/b2ed5b05f7224f76b575fd05ca07bceb
Autor:
Leonie M. Weskamm, Paulina Tarnow, Charlotte Harms, Melanie Huchon, Matthijs P. Raadsen, Monika Friedrich, Laura Rübenacker, Cordula Grüttner, Mariana G. Garcia, Till Koch, Stephan Becker, Gerd Sutter, Edouard Lhomme, Bart L. Haagmans, Anahita Fathi, Sandra M. Blois, Christine Dahlke, Laura Richert, Marylyn M. Addo
Publikováno v:
iScience, Vol 27, Iss 8, Pp 110470- (2024)
Summary: Besides neutralizing antibodies, which are considered an important measure for vaccine immunogenicity, Fc-mediated antibody functions can contribute to antibody-mediated protection. They are strongly influenced by structural antibody propert
Externí odkaz:
https://doaj.org/article/608910de3c4f4ba4ae8af02bb275eee1
Autor:
Leonie Mayer, Leonie M. Weskamm, Anahita Fathi, Maya Kono, Jasmin Heidepriem, Verena Krähling, Sibylle C. Mellinghoff, My Linh Ly, Monika Friedrich, Svenja Hardtke, Saskia Borregaard, Thomas Hesterkamp, Felix F. Loeffler, Asisa Volz, Gerd Sutter, Stephan Becker, Christine Dahlke, Marylyn M. Addo
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-14 (2024)
Abstract In response to the COVID-19 pandemic, multiple vaccines were developed using platforms such as viral vectors and mRNA technology. Here, we report humoral and cellular immunogenicity data from human phase 1 clinical trials investigating two r
Externí odkaz:
https://doaj.org/article/5b1fea1ceb2340e395b1e673ec685d27
Autor:
Christian Meyer zu Natrup, Lisa-Marie Schünemann, Giulietta Saletti, Sabrina Clever, Vanessa Herder, Sunitha Joseph, Marina Rodriguez, Ulrich Wernery, Gerd Sutter, Asisa Volz
Publikováno v:
Emerging Infectious Diseases, Vol 29, Iss 6, Pp 1236-1239 (2023)
We developed an ELISPOT assay for evaluating Middle East respiratory syndrome coronavirus (MERS-CoV)‒specific T-cell responses in dromedary camels. After single modified vaccinia virus Ankara-MERS-S vaccination, seropositive camels showed increased
Externí odkaz:
https://doaj.org/article/cf3fc1d60ad049a2b69d302403f46045
Autor:
Jeffy G. Mattathil, Asisa Volz, Olusegun O. Onabajo, Sean Maynard, Sandra L. Bixler, Xiaoying X. Shen, Diego Vargas-Inchaustegui, Marjorie Robert-Guroff, Celia Lebranche, Georgia Tomaras, David Montefiori, Gerd Sutter, Joseph J. Mattapallil
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Mucosal surfaces are a primary route of HIV entry, yet the compartmentalisation between mucosal and peripheral immune systems remain a challenge for HIV vaccine candidates. Authors utilise a combination of intranodal tonsil MALT and systemic vaccinat
Externí odkaz:
https://doaj.org/article/5c95e638f47643898cb93e8cea9c171f
Autor:
Sabrina Clever, Leonard Limpinsel, Christian Meyer zu Natrup, Lisa-Marie Schünemann, Georg Beythien, Malgorzata Rosiak, Kirsten Hülskötter, Katharina Manuela Gregor, Tamara Tuchel, Georgia Kalodimou, Astrid Freudenstein, Satendra Kumar, Wolfgang Baumgärtner, Gerd Sutter, Alina Tscherne, Asisa Volz
Publikováno v:
Viruses, Vol 16, Iss 3, p 417 (2024)
The sudden emergence of SARS-CoV-2 demonstrates the need for new vaccines that rapidly protect in the case of an emergency. In this study, we developed a recombinant MVA vaccine co-expressing SARS-CoV-2 prefusion-stabilized spike protein (ST) and SAR
Externí odkaz:
https://doaj.org/article/dce965dac07f41e881175ae99326794b
Autor:
Kim Thi Hoang Do, Stefanie Willenzon, Jasmin Ristenpart, Anika Janssen, Asisa Volz, Gerd Sutter, Reinhold Förster, Berislav Bošnjak
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
Background and aimsModified Vaccinia virus Ankara (MVA) represents a promising vaccine vector for respiratory administration to induce protective lung immunity including tertiary lymphoid structure, the bronchus-associated lymphoid tissue (BALT). How
Externí odkaz:
https://doaj.org/article/de6be87cc416489f89eb6de74080f119
Autor:
Jana Beicht, Mareike Kubinski, Isabel Zdora, Christina Puff, Jeannine Biermann, Thomas Gerlach, Wolfgang Baumgärtner, Gerd Sutter, Albert D. M. E. Osterhaus, Chittappen Kandiyil Prajeeth, Guus F. Rimmelzwaan
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionTick-borne encephalitis virus (TBEV) is one of the most relevant tick-transmitted neurotropic arboviruses in Europe and Asia and the causative agent of tick-borne encephalitis (TBE). Annually more than 10,000 TBE cases are reported despit
Externí odkaz:
https://doaj.org/article/a2faeb296baf45aca76be3b627a5edda
Autor:
Sabrina Clever, Lisa-Marie Schünemann, Federico Armando, Christian Meyer zu Natrup, Tamara Tuchel, Alina Tscherne, Malgorzata Ciurkiewicz, Wolfgang Baumgärtner, Gerd Sutter, Asisa Volz
Publikováno v:
Vaccines, Vol 12, Iss 1, p 52 (2024)
Aging is associated with a decline in immune system functionality. So-called immunosenescence may impair the successful vaccination of elderly people. Thus, improved vaccination strategies also suitable for an aged immune system are required. Modifie
Externí odkaz:
https://doaj.org/article/ef0ed1f946e847349fdcdb39a1bdf45f
Autor:
Mareike Kubinski, Jana Beicht, Thomas Gerlach, Amare Aregay, Albert D. M. E. Osterhaus, Alina Tscherne, Gerd Sutter, Chittappen Kandiyil Prajeeth, Guus F. Rimmelzwaan
Publikováno v:
Vaccines, Vol 12, Iss 1, p 105 (2024)
Tick-borne encephalitis (TBE) is a serious neurological disease caused by TBE virus (TBEV). Because antiviral treatment options are not available, vaccination is the key prophylactic measure against TBEV infections. Despite the availability of effect
Externí odkaz:
https://doaj.org/article/6995d27a9c67459589803e595b8ce85e