Zobrazeno 1 - 10
of 217
pro vyhledávání: '"Gerd, Hause"'
Autor:
Tim Kingreen, Stefanie Kewitz-Hempel, Christian Rohde, Gerd Hause, Cord Sunderkötter, Dennis Gerloff
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Invasive growth is a critical process in tumor progression, requiring the activation of various molecular processes in tumor cells at the invasive front. Intercellular communication between heterogeneous tumor cells enhances cellular activat
Externí odkaz:
https://doaj.org/article/6a25d09d622840aa9966b69db9f1b09e
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Pancreatic stellate cells (PSC) are one source of cancer-associated fibroblasts (CAF) and play, therefore, an essential role in pancreatic ductal adenocarcinoma (PDA). Paracrine signalling between PDA cells and CAF has been widely studied, y
Externí odkaz:
https://doaj.org/article/f1f8916a50834787be736600dc324404
Autor:
Lisa Schmidt, Christian Tüting, Fotis L. Kyrilis, Farzad Hamdi, Dmitry A. Semchonok, Gerd Hause, Annette Meister, Christian Ihling, Milton T. Stubbs, Andrea Sinz, Panagiotis L. Kastritis
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-12 (2024)
Abstract The high abundance of most viruses in infected host cells benefits their structural characterization. However, endogenous viruses are present in low copy numbers and are therefore challenging to investigate. Here, we retrieve cell extracts e
Externí odkaz:
https://doaj.org/article/b2213ea566234e8b8a773838896395a9
Autor:
Stefanie Kewitz‐Hempel, Nicola Windisch, Gerd Hause, Lutz Müller, Cord Sunderkötter, Dennis Gerloff
Publikováno v:
Journal of Extracellular Vesicles, Vol 13, Iss 9, Pp n/a-n/a (2024)
Abstract In melanoma, carcinoma‐associated fibroblasts (CAFs) are important cellular components in the tumour microenvironment due to their potential to promote tumour growth and metastatic spread of malignant cells. Melanoma cells have the ability
Externí odkaz:
https://doaj.org/article/afe2576122cf4d9bb5cab3b1c6a9657c
Autor:
Ioannis Skalidis, Fotis L. Kyrilis, Christian Tüting, Farzad Hamdi, Toni K. Träger, Jaydeep Belapure, Gerd Hause, Marta Fratini, Francis J. O’Reilly, Ingo Heilmann, Juri Rappsilber, Panagiotis L. Kastritis
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-15 (2023)
Abstract The oxoglutarate dehydrogenase complex (OGDHc) participates in the tricarboxylic acid cycle and, in a multi-step reaction, decarboxylates α-ketoglutarate, transfers succinyl to CoA, and reduces NAD+. Due to its pivotal role in metabolism, O
Externí odkaz:
https://doaj.org/article/35a1a0d0d41747198ab9194230348b40
Publikováno v:
Frontiers in Plant Science, Vol 14 (2023)
For many metabolites, the major barrier between cytosol and mitochondrial matrix is the inner membrane of mitochondria, the site of the respiratory electron transport chain. In consequence, it houses numerous transporters which facilitate the control
Externí odkaz:
https://doaj.org/article/8e5d2c5913334e0fb921d0676bd40676
Autor:
Dennis Gerloff, Stefanie Kewitz-Hempel, Gerd Hause, Jovine Ehrenreich, Linda Golle, Tim Kingreen, Cord Sunderkötter
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Extracellular vesicles (EVs) are important mediators in the intercellular communication, influencing the function and phenotype of different cell types within the tumor micro-milieu and thus promote tumor progression. Since EVs safely transport packa
Externí odkaz:
https://doaj.org/article/783a0a47f98e473289882abd897b2744
Autor:
Susann Allelein, Paula Medina-Perez, Ana Leonor Heitor Lopes, Sabrina Rau, Gerd Hause, Andreas Kölsch, Dirk Kuhlmeier
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Extracellular vesicles (EVs) have attracted interest due to their ability to provide diagnostic information from liquid biopsies. Cells constantly release vesicles divers in size, content and features depending on the biogenesis, origin and
Externí odkaz:
https://doaj.org/article/a42e3d10d3c249a29323c9224424764c
Publikováno v:
ACS Omega, Vol 5, Iss 30, Pp 19020-19028 (2020)
Externí odkaz:
https://doaj.org/article/5660e4d2a20a4c98857307789f76a05d
Autor:
Julia Grimmer, Stefan Helm, Dirk Dobritzsch, Gerd Hause, Gerta Shema, René P. Zahedi, Sacha Baginsky
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Most chloroplast proteins are imported from the cytosol and thus transiently exposed to the cytosolic proteasome. Here the authors show that impairment of the cytosolic proteasome can elevate precursor protein abundance and photosynthetic activity su
Externí odkaz:
https://doaj.org/article/69490422533c4a51abd07417825ad799