Growth Hormone Receptor Regulation in Cancer and Chronic Diseases

Autor: Ger J. Strous, Ana Da Silva Almeida, Joyce Putters, Julia Schantl, Magdalena Sedek, Johan A. Slotman, Tobias Nespital, Gerco C. Hassink, Jan A. Mol

Publikováno v: Frontiers in Endocrinology, Vol 11 (2020)

The GHR signaling pathway plays important roles in growth, metabolism, cell cycle control, immunity, homeostatic processes, and chemoresistance via both the JAK/STAT and the SRC pathways. Dysregulation of GHR signaling is associated with various dise

Externí odkaz: https://doaj.org/article/f54837c6dbd34bc3a5f7c91870b0008a

The Association between Hypoxia-Induced Low Activity and Apoptosis Strongly Resembles That between TTX-Induced Silencing and Apoptosis

Autor: Domitilla Taxis di Bordonia e Valnigra, Gerco C. Hassink, Marloes R. Levers, Monica Frega, Jeannette Hofmeijer, Michel J. A. M. van Putten, Joost le Feber

Publikováno v: International journal of molecular sciences, 23(5):2754. MDPI
International Journal of Molecular Sciences; Volume 23; Issue 5; Pages: 2754

In the penumbra of a brain infarct, neurons initially remain structurally intact, but perfusion is insufficient to maintain neuronal activity at physiological levels. Improving neuronal recovery in the penumbra has large potential to advance recovery

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8fbd12324d63686b374f0aaac8949c5
https://research.utwente.nl/en/publications/0d2b5bae-4e4a-40c4-b19b-26bfe2f36ca4