Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Gerben Bouma"'
Autor:
Stefania Vetrano, Gerben Bouma, Robert J. Benschop, Thomas Birngruber, Antonio Costanzo, G. R. A. M. D’Haens, Loredana Frasca, Rainer Hillenbrand, Lars Iversen, Claus Johansen, Arthur Kaser, Hans J. P. M. Koenen, Christa Noehammer, Laurent Peyrin-Biroulet, Jeroen Raes, Leonardo Ricotti, Philip Rosenstiel, Venkata P. Satagopam, Stefan Schreiber, Severine Vermeire, Andreas Wollenberg, Stephan Weidinger, Daniel Ziemek, Silvio Danese, ImmUniverse Consortium, Alessandro Armuzzi, Alessia Butera, Andrea Cafarelli, Lucia Ciglar, Ellen van den Bogaard, Elke MGJ de Jong, Ernst Dow, Marjolijn Duijvenstein, Ahmed Essaghir, Rebecca Favaro, Gionata Fiorino, Soumyabrata Ghosh, Wei Gu, Robert Häsler, Xuehui He, Roberto Lande, Judith Logmans, Christoph Magnes, Karl Nocka, Loulou Peisl, Samuel Pineda Chavez, Angela Sorriento, Klemens Vierlinger, Laurien Waaijer, Xinhui Wang, Nicolas Wisniacki, Mary Zuniga
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Immune mediated inflammatory diseases (IMIDs) are a heterogeneous group of debilitating, multifactorial and unrelated conditions featured by a dysregulated immune response leading to destructive chronic inflammation. The immune dysregulation can affe
Externí odkaz:
https://doaj.org/article/25c0b3e1103d4243ac5ad47318b6a393
Autor:
Susan B Laffan, Andrew S Thomson, Shing Mai, Cindy Fishman, Takahito Kambara, Kiran Nistala, James T Raymond, Shugui Chen, Thulasi Ramani, Laura Pageon, Rodd Polsky, Mark Watkins, Gemma Ottolangui, John R White, Curtis Maier, Michael Herdman, Gerben Bouma
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0231655 (2020)
Despite the potential for the chemokine class as therapeutic targets in immune mediated disease, success has been limited. Many chemokines can bind to multiple receptors and many receptors have multiple ligands, with few exceptions. One of those exce
Externí odkaz:
https://doaj.org/article/ee33790a5c0946eb8e5ea303f460bcc0
Autor:
Cees E. van der Poel, Goran Bajic, Charles W. Macaulay, Theo van den Broek, Christian D. Ellson, Gerben Bouma, Gabriel D. Victora, Søren E. Degn, Michael C. Carroll
Publikováno v:
Cell Reports, Vol 29, Iss 9, Pp 2745-2755.e4 (2019)
Summary: Follicular dendritic cells (FDCs), a rare and enigmatic stromal cell type in the B cell follicles of secondary lymphoid organs, store and present antigen to B cells. While essential for germinal center (GC) responses, their exact role during
Externí odkaz:
https://doaj.org/article/808ea57c369d473fa9c886315dd46bd7
Autor:
Pamela P. Lee, Damián Lobato-Márquez, Nayani Pramanik, Andrea Sirianni, Vanessa Daza-Cajigal, Elizabeth Rivers, Alessia Cavazza, Gerben Bouma, Dale Moulding, Kjell Hultenby, Lisa S. Westerberg, Michael Hollinshead, Yu-Lung Lau, Siobhan O. Burns, Serge Mostowy, Mona Bajaj-Elliott, Adrian J. Thrasher
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Wiskott-Aldrich syndrome protein (WASp) is essential for controlling the cytoskeleton, but its function in innate immunity is unclear. Here the authors show that WASp deficiency is associated with dysregulated septin cage formation, excessive inflamm
Externí odkaz:
https://doaj.org/article/7f189439f64c4318ac3cf0baaa3c3614
Autor:
Marisa A. P. Baptista, Marton Keszei, Mariana Oliveira, Karen K. S. Sunahara, John Andersson, Carin I. M. Dahlberg, Austen J. Worth, Agne Liedén, I-Chun Kuo, Robert P. A. Wallin, Scott B. Snapper, Liv Eidsmo, Annika Scheynius, Mikael C. I. Karlsson, Gerben Bouma, Siobhan O. Burns, Mattias N. E. Forsell, Adrian J. Thrasher, Susanne Nylén, Lisa S. Westerberg
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
Wiskott–Aldrich syndrome (WAS) is a severe X-linked primary immunodeficiency syndrome. Here, the authors show that loss of WAS gene in dendritic cells results in increased activity of Rac2, increase of phagosomal pH, and more efficient cross-presen
Externí odkaz:
https://doaj.org/article/b30cb5531b534a4c9f3e0c5bebf69da8
Autor:
Chiara Beilin, Kaushik Choudhuri, Gerben Bouma, Dessislava Malinova, Jaime Llodra, David L. Stokes, Motumu Shimaoka, Timothy A. Springer, Michael L. Dustin, Adrian J. Thrasher, Siobhan O. Burns
Publikováno v:
Wellcome Open Research, Vol 3 (2018)
Background: Mutations of the common cytokine receptor gamma chain (γc) cause Severe Combined Immunodeficiency characterized by absent T and NK cell development. Although stem cell therapy restores these lineages, residual immune defects are observed
Externí odkaz:
https://doaj.org/article/9aa513bc8f90470ea569c3a6faafd9ca
Autor:
John Anderson, Nichola Cooper, Steven J. Howe, Ayad Eddaoudi, Jo Buddle, Ben Seddon, Rebecca Wallace, Daniel Morgenstern, Gerben Bouma, Mengyong Yan, Nourredine Himoudi
Supplementary Figure 2 from Migratory and Antigen Presentation Functions of IFN-Producing Killer Dendritic Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13ce02489bba4cc881cad0fe25835947
https://doi.org/10.1158/0008-5472.22378145
https://doi.org/10.1158/0008-5472.22378145
Autor:
John Anderson, Nichola Cooper, Steven J. Howe, Ayad Eddaoudi, Jo Buddle, Ben Seddon, Rebecca Wallace, Daniel Morgenstern, Gerben Bouma, Mengyong Yan, Nourredine Himoudi
Supplementary Figure 1 from Migratory and Antigen Presentation Functions of IFN-Producing Killer Dendritic Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19240a75171b3ce3c56bf9e87ff84db6
https://doi.org/10.1158/0008-5472.22378148
https://doi.org/10.1158/0008-5472.22378148
Autor:
John Anderson, Nichola Cooper, Steven J. Howe, Ayad Eddaoudi, Jo Buddle, Ben Seddon, Rebecca Wallace, Daniel Morgenstern, Gerben Bouma, Mengyong Yan, Nourredine Himoudi
Supplementary Figure Legends 1-2 from Migratory and Antigen Presentation Functions of IFN-Producing Killer Dendritic Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::491c1dfef055f0d0e313a3ce41c753b2
https://doi.org/10.1158/0008-5472.22378142
https://doi.org/10.1158/0008-5472.22378142
Autor:
Stephen H. Trulli, J. David Taylor, Shugui Chen, Michael Herdman, Charles S Hottenstein, Michael Byrne, Joseph Minetti, John R. White, Andrew S. Thomson, Gerben Bouma, Shing H. Mai
Publikováno v:
The Journal of Immunology. 206:1067-1076
mAbs have revolutionized the treatment of autoimmune disorders. Even though mAbs have shown impressive efficacy in blocking T cell or B cell activation and/or recruitment to sites of inflammation, this group of biologicals are not devoid of adverse e