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Increased Hepatic PDGF-AA Signaling Mediates Liver Insulin Resistance in Obesity-Associated Type 2 Diabetes

Autor: Abderrahmani, A, Yengo, L, Caiazzo, R, Canouil, M, Cauchi, S, Raverdy, V, Plaisance, V, Pawlowski, V, Lobbens, S, Maillet, J, Rolland, L, Boutry, R, Queniat, G, Kwapich, M, Tenenbaum, M, Bricambert, J, Saussenthaler, S, Anthony, E, Jha, P, Derop, J, Sand, O, Rabearivelo, I, Leloire, A, Pigeyre, M, Daujat-Chavanieu, M, Gerbal-Chaloin, S, Dayeh, T, Lassailly, G, Mathurin, P, Staels, B, Auwerx, J, Schurmann, A, Postic, C, Schafmayer, C, Hampe, J, Bonnefond, A, Pattou, F, Froguel, P

Publikováno v: Diabetes
Diabetes, 2018, 67 (7), pp.1310-1321. ⟨10.2337/db17-1539⟩
Diabetes, American Diabetes Association, 2018, 67 (7), pp.1310-1321. ⟨10.2337/db17-1539⟩

In type 2 diabetes (T2D), hepatic insulin resistance is strongly associated with nonalcoholic fatty liver disease (NAFLD). In this study, we hypothesized that the DNA methylome of livers from patients with T2D compared with livers of individuals with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::7caea1ff0303921e008e575c4cb29c5b
https://hal.umontpellier.fr/hal-01837153

Cross-talk between xenobiotic detoxication and other signalling pathways: clinical and toxicological consequences.

Autor: Pascussi, J.-M.¹, Gerbal-Chaloin, S.¹, Drocourt, L.¹, Assénat, E.², Larrey, D.², Pichard-Garcia, L.¹, Vilarem, M.-J.¹, Maurel, P.¹ maurel@montp.inserm.fr

Publikováno v: Xenobiotica. Jul2004, Vol. 34 Issue 7, p633-664. 32p.

p53-paralog DNp73 oncogene is repressed by IFNα/STAT2 through the recruitment of the Ezh2 polycomb group transcriptional repressor

Autor: Testoni, B, Schinzari, V, Guerrieri, Francesca, GERBAL CHALOIN, S, Blandino, G, Levrero, Massimo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3686::f7d83ebc87dc9e048332bdb413c7473f
http://hdl.handle.net/11573/378211

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