Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Gerasimos J Zaharatos"'
Autor:
Sandhya Vasan, Sarah J Schlesinger, Zhiwei Chen, Arlene Hurley, Angela Lombardo, Soe Than, Phumla Adesanya, Catherine Bunce, Mark Boaz, Rosanne Boyle, Eddy Sayeed, Lorna Clark, Daniel Dugin, Mar Boente-Carrera, Claudia Schmidt, Qing Fang, LeiBa, Yaoxing Huang, Gerasimos J Zaharatos, David F Gardiner, Marina Caskey, Laura Seamons, Martin Ho, Len Dally, Carol Smith, Josephine Cox, Dilbinder Gill, Jill Gilmour, Michael C Keefer, Patricia Fast, David D Ho
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8816 (2010)
We conducted a Phase I dose-escalation trial of ADMVA, a Clade-B'/C-based HIV-1 candidate vaccine expressing env, gag, pol, nef, and tat in a modified vaccinia Ankara viral vector. Sequences were derived from a prevalent circulating HIV-1 recombinant
Externí odkaz:
https://doaj.org/article/25b6bfc4047d47d09e9a293a9d14fcdd
Autor:
Yves Longtin, Leighanne O. Parkes, Hugues Charest, Stacy Rajarison, Gerasimos J. Zaharatos, Judith Fafard, Michel Roger, Gaston De Serres
Publikováno v:
Infection Control and Hospital Epidemiology
We performed viral culture of nasopharyngeal specimens in individuals aged 79 and older, infected with severe acute respiratory coronavirus virus 2 (SARS-CoV-2), 10 days after symptom onset. A positive viral culture was obtained in 10 (45%) of 22 par
Autor:
John P, Thornhill, Sapha, Barkati, Sharon, Walmsley, Juergen, Rockstroh, Andrea, Antinori, Luke B, Harrison, Romain, Palich, Achyuta, Nori, Iain, Reeves, Maximillian S, Habibi, Vanessa, Apea, Christoph, Boesecke, Linos, Vandekerckhove, Michal, Yakubovsky, Elena, Sendagorta, Jose L, Blanco, Eric, Florence, Davide, Moschese, Fernando M, Maltez, Abraham, Goorhuis, Valerie, Pourcher, Pascal, Migaud, Sebastian, Noe, Claire, Pintado, Fabrizio, Maggi, Ann-Brit E, Hansen, Christian, Hoffmann, Jezer I, Lezama, Cristina, Mussini, AnnaMaria, Cattelan, Keletso, Makofane, Darrell, Tan, Silvia, Nozza, Johannes, Nemeth, Marina B, Klein, Chloe M, Orkin, Gerasimos J, Zaharatos
Publikováno v:
SHARE-net Clinical Group 2022, ' Monkeypox Virus Infection in Humans across 16 Countries-April-June 2022 ', The New England Journal of Medicine, vol. 387, no. 8, pp. 679-691 . https://doi.org/10.1056/NEJMoa2207323
The New England journal of medicine, 387(8), 679-691. Massachussetts Medical Society
The New England journal of medicine, 387(8), 679-691. Massachussetts Medical Society
BACKGROUND: Before April 2022, monkeypox virus infection in humans was seldom reported outside African regions where it is endemic. Currently, cases are occurring worldwide. Transmission, risk factors, clinical presentation, and outcomes of infection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9061b68612348a3f2d2da86ef5a14db0
https://hdl.handle.net/11380/1289204
https://hdl.handle.net/11380/1289204
Autor:
Gabrielle Gendron-Lepage, Cedric P. Yansouni, Rachel Corsini, Antonia Dibernardo, Chelsea Caya, Michael A. Drebot, Mehdi Benlarbi, Kathy Manguiat, Momar Ndao, Jérémie Prévost, Matthew P. Cheng, Gerasimos J Zaharatos, Renée Bazin, Andrés Finzi, Romain Gasser, L. Robbin Lindsay, Guillaume Beaudoin-Bussières, Heidi Wood, Emelissa J Mendoza, Jesse Papenburg
BackgroundSARS-CoV-2 surrogate neutralization assays that obviate the need for viral culture offer substantial advantages regarding throughput and cost. The cPass SARS-CoV-2 Neutralization Antibody Detection Kit (Genscript) is the first such commerci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6bc0c06fb56faed51fcef268bbc9b33
https://doi.org/10.1101/2021.01.23.21250325
https://doi.org/10.1101/2021.01.23.21250325
Autor:
Leighanne O Parkes, Matthew P. Cheng, Kym Antonation, Gerasimos J. Zaharatos, Sadjia BekalS. Bekal
Publikováno v:
Official Journal of the Association of Medical Microbiology and Infectious Disease Canada. 3:108-113
Melioidosis, a “great mimicker,” is a potentially severe and fatal illness. In this paper we present a Québec case of imported pulmonary melioidosis in a young patient who failed to demonstrate any of the risk factors traditionally associated wi
Publikováno v:
Viruses
Viruses, Vol 10, Iss 3, p 100 (2018)
Viruses; Volume 10; Issue 3; Pages: 100
Viruses, Vol 10, Iss 3, p 100 (2018)
Viruses; Volume 10; Issue 3; Pages: 100
Flagellin’s potential as a vaccine adjuvant has been increasingly explored over the last three decades. Monomeric flagellin proteins are the only known agonists of Toll-like receptor 5 (TLR5). This interaction evokes a pro-inflammatory state that i
Autor:
Jiaming Liang, Lara Ajamian, Luca Melnychuk, Gerasimos J. Zaharatos, Mark A. Wainberg, Patrick Jean-Pierre, Romina Gheorghe
Publikováno v:
Vaccine. 35(20)
A limited number of sites on the HIV-1 Envelope protein are vulnerable to broadly neutralizing antibodies (bnAbs). One of these sites, the membrane proximal external region (MPER), is located at the C-terminus of the gp41 ectodomain (gp41ecto). This
Autor:
Craig S. Pace, Jian Yu, Yang Song, Yaoxing Huang, David D. Ho, Gerasimos J. Zaharatos, Sandhya Vasan
Publikováno v:
Vaccine. 30:42-50
Using murine IgG subclass molecules (IgG1 or IgG2a) synthetically fused to HIV-1 or influenza test antigens, we explored the potential for IgG Fc scaffolds to augment immunogenicity. Each antigen (Ag) was grafted onto a hinge-Fc scaffold containing a
Publikováno v:
New England Journal of Medicine. 365:637-646
fers among HIV variants. Indeed, we have limited knowledge of resistance muta tions in non-B subtypes of HIV type 1 (HIV-1) and their clinical relevance, despite the fact that more than 90% of patients with HIV-1 infection worldwide have non– subty
Publikováno v:
Annals of medicine. 45(3)
A combination of antiretroviral drugs (ARVs) is necessary to achieve sustained virologic suppression of HIV viral load (50 copies/mL). Rilpivirine (RPV) is a potent new non-nucleoside reverse transcriptase inhibitor (NNRTI) that has the potential to