Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Gerasimos Anagnostopoulos"'
Autor:
Gerasimos Anagnostopoulos, Ester Saavedra, Flavia Lambertucci, Omar Motiño, Jordan Dimitrov, David Roiz-Valle, Victor Quesada, Karla Alvarez-Valadez, Hui Chen, Allan Sauvat, Yan Rong, Uxía Nogueira-Recalde, Sijing Li, Léa Montégut, Mojgan Djavaheri-Mergny, Maria Castedo, Carlos Lopez-Otin, Maria Chiara Maiuri, Isabelle Martins, Guido Kroemer
Publikováno v:
Cell Death and Disease, Vol 15, Iss 4, Pp 1-11 (2024)
Abstract Acyl-CoA binding protein (ACBP) encoded by diazepam binding inhibitor (DBI) is an extracellular inhibitor of autophagy acting on the gamma-aminobutyric acid A receptor (GABAAR) γ2 subunit (GABAARγ2). Here, we show that lipoanabolic diets c
Externí odkaz:
https://doaj.org/article/6156a26a97494404ab21b5b9e7b5c530
Autor:
Gerasimos Anagnostopoulos, Omar Motiño, Sijing Li, Vincent Carbonnier, Hui Chen, Valentina Sica, Sylvère Durand, Mélanie Bourgin, Fanny Aprahamian, Nitharsshini Nirmalathasan, Romain Donne, Chantal Desdouets, Marcelo Simon Sola, Konstantina Kotta, Léa Montégut, Flavia Lambertucci, Didier Surdez, Grossetête Sandrine, Olivier Delattre, Maria Chiara Maiuri, José Manuel Bravo-SanPedro, Isabelle Martins, Guido Kroemer
Publikováno v:
Cell Death and Disease, Vol 13, Iss 4, Pp 1-15 (2022)
Abstract Acyl-coenzyme-A-binding protein (ACBP), also known as a diazepam-binding inhibitor (DBI), is a potent stimulator of appetite and lipogenesis. Bioinformatic analyses combined with systematic screens revealed that peroxisome proliferator-activ
Externí odkaz:
https://doaj.org/article/9d621ffca98c4f8181d6d34f52f24bcd
Autor:
Adrien Joseph, Hui Chen, Gerasimos Anagnostopoulos, Léa Montégut, Antoine Lafarge, Omar Motiño, Maria Castedo, Maria Chiara Maiuri, Karine Clément, Safae Terrisse, Anne Laure Martin, Ines Vaz-Luis, Fabrice Andre, Franziska Grundler, Françoise Wilhelmi de Toledo, Frank Madeo, Laurence Zitvogel, François Goldwasser, Benoit Blanchet, Frédéric Fumeron, Ronan Roussel, Isabelle Martins, Guido Kroemer
Publikováno v:
Cell Death and Disease, Vol 12, Iss 6, Pp 1-14 (2021)
Abstract In mice, the plasma concentrations of the appetite-stimulatory and autophagy-inhibitory factor acyl-coenzyme A binding protein (ACBP, also called diazepam-binding inhibitor, DBI) acutely increase in response to starvation, but also do so upo
Externí odkaz:
https://doaj.org/article/87eab42d99e743b7ae47f07c8dddc3bc
Autor:
Gerasimos Anagnostopoulos, Omar Motiño, Sijing Li, Vincent Carbonnier, Hui Chen, Valentina Sica, Sylvère Durand, Mélanie Bourgin, Fanny Aprahamian, Nitharsshini Nirmalathasan, Romain Donne, Chantal Desdouets, Marcelo Simon Sola, Konstantina Kotta, Léa Montégut, Flavia Lambertucci, Didier Surdez, Grossetête Sandrine, Olivier Delattre, Maria Chiara Maiuri, José Manuel Bravo-San Pedro, Isabelle Martins, Guido Kroemer
Publikováno v:
Cell Death and Disease, Vol 13, Iss 5, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/079b77792a314dfb93dbcdc0d5aaa91b
Autor:
Chrysanthi Voutyraki, Alexandros Choromidis, Vasiliki Theodorou, Christina Efraimoglou, Gerasimos Anagnostopoulos, Srivathsa S. Magadi, Sofia Grammenoudi, Evanthia Zacharioudaki, Christos Delidakis
Publikováno v:
The International Journal of Developmental Biology. 66:211-222
Background: Neural stem cells (NSC) in divide asymmetrically to generate one cell that retains stem cell identity and another that is routed to differentiation. Prolonged mitotic activity of the NSCs gives rise to the plethora of neurons and glial ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b725ee91dfc6d1c5db5f71631d10a2fd
https://doi.org/10.1387/ijdb.210187cd
https://doi.org/10.1387/ijdb.210187cd
Autor:
Léa Montégut, Adrien Joseph, Hui Chen, Mahmoud Abdellatif, Christoph Ruckenstuhl, Omar Motiño, Flavia Lambertucci, Gerasimos Anagnostopoulos, Sylvie Lachkar, Silvia Dichtinger, Maria Chiara Maiuri, François Goldwasser, Benoit Blanchet, Frédéric Fumeron, Isabelle Martins, Frank Madeo, Guido Kroemer
Publikováno v:
Aging Cell. 22
Autophagy defects accelerate aging, while stimulation of autophagy decelerates aging. Acyl-coenzyme A binding protein (ACBP), which is encoded by a diazepam-binding inhibitor (DBI), acts as an extracellular feedback regulator of autophagy. As shown h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c205d63115eea1fa88980c09050af391
https://doi.org/10.1111/acel.13751
https://doi.org/10.1111/acel.13751
Autor:
Omar Motiño, Flavia Lambertucci, Gerasimos Anagnostopoulos, Sijing Li, Isabelle Martins, Guido Kroemer
Publikováno v:
Autophagy.
DBI/ACBP (diazepam binding inhibitor, also known as acyl coenzyme A binding protein), acts as a paracrine inhibitor of macroautophagy/autophagy. We characterized a monoclonal antibody neutralizing mouse DBI/ACBP (a-DBI) for its cytoprotective effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a40e16a57e2146c02565b8c0d7852a25
https://pubmed.ncbi.nlm.nih.gov/36198092
https://pubmed.ncbi.nlm.nih.gov/36198092
Autor:
Omar Motiño, Flavia Lambertucci, Gerasimos Anagnostopoulos, Sijing Li, Jihoon Nah, Francesca Castoldi, Laura Senovilla, Léa Montégut, Hui Chen, Sylvère Durand, Mélanie Bourgin, Fanny Aprahamian, Nitharsshini Nirmalathasan, Karla Alvarez-Valadez, Allan Sauvat, Vincent Carbonnier, Mojgan Djavaheri-Mergny, Federico Pietrocola, Junichi Sadoshima, Maria Chiara Maiuri, Isabelle Martins, Guido Kroemer
Acyl-coenzyme A (CoA)–binding protein (ACBP), also known as diazepam-binding inhibitor (DBI), is an extracellular feedback regulator of autophagy. Here, we report that injection of a monoclonal antibody neutralizing ACBP/DBI (α-DBI) protects the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::232d997c5521d9f8e03a0b19602668d4
http://hdl.handle.net/10261/296251
http://hdl.handle.net/10261/296251
Autor:
Chrysanthi, Voutyraki, Alexandros, Choromidis, Vasiliki, Theodorou, Christina, Efraimoglou, Gerasimos, Anagnostopoulos, Srivathsa S, Magadi, Sofia, Grammenoudi, Evanthia, Zacharioudaki, Christos, Delidakis
Publikováno v:
The International journal of developmental biology. 66(1-2-3)
Neural stem cells (NSC) in divide asymmetrically to generate one cell that retains stem cell identity and another that is routed to differentiation. Prolonged mitotic activity of the NSCs gives rise to the plethora of neurons and glial cells that wir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::44890d9eeabcb8c2e9f2059ea3f7cc21
https://pubmed.ncbi.nlm.nih.gov/34881794
https://pubmed.ncbi.nlm.nih.gov/34881794
Autor:
Gerasimos, Anagnostopoulos, Léa, Montégut, Hui, Chen, Vincent, Carbonnier, Isabelle, Martins, Khady, Mangane, Abdelkrim, Mannioui, Alex, Bois, Elisa Elena, Baracco, Maria Chiara, Maiuri, Guido, Kroemer
Publikováno v:
Methods in cell biology. 165
Autophagy is an evolutionarily conserved biological process required for the turnover of the cytoplasm of eukaryotic cell. Beyond its catabolic nature, autophagy has a plethora of pro-survival functions, thus combatting hypoxia, nutrient shortage, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a51191bf378e7ddddc9d57b949fc392f
https://pubmed.ncbi.nlm.nih.gov/34311861
https://pubmed.ncbi.nlm.nih.gov/34311861