Non-immunogenic recombinant staphylokinase versus alteplase for patients with acute ischaemic stroke 4·5 h after symptom onset in Russia (FRIDA): a randomised, open label, multicentre, parallel-group, non-inferiority trial.

Autor: Gusev EI; Department of Neurology, Pirogov Russian National Research Medical University of the Russian Ministry of Health, Moscow, Russia. Electronic address: egusev2339@gmail.com., Martynov MY; Department of Neurology, Pirogov Russian National Research Medical University of the Russian Ministry of Health, Moscow, Russia., Nikonov AA; Department of Neurology, Pirogov Russian National Research Medical University of the Russian Ministry of Health, Moscow, Russia., Shamalov NA; Federal State Budgetary Institution, Federal Center of Brain Research and Neurotechnologies of the Federal Medical Biological Agency, Moscow, Russia., Semenov MP; Medical Department, Peoples' Friendship University of Russia, Moscow, Russia., Gerasimets EA; Medical Department, Peoples' Friendship University of Russia, Moscow, Russia., Yarovaya EB; Faculty of Mechanics and Mathematics, Lomonosov Moscow State University, Moscow, Russia., Semenov AM; Medical Department, Peoples' Friendship University of Russia, Moscow, Russia; SuperGene, Moscow, Russia., Archakov AI; Institute of Biomedical Chemistry, Moscow, Russia., Markin SS; Institute of Biomedical Chemistry, Moscow, Russia; SuperGene, Moscow, Russia.

Publikováno v: The Lancet. Neurology [Lancet Neurol] 2021 Sep; Vol. 20 (9), pp. 721-728.