Výsledky vyhledávání - "Gerardo R, Vasta"

Akademický článek

Lacking catalase, a protistan parasite draws on its photosynthetic ancestry to complete an antioxidant repertoire with ascorbate peroxidase

Autor: Eric J. Schott, Santiago Di Lella, Tsvetan R. Bachvaroff, L. Mario Amzel, Gerardo R. Vasta

Publikováno v: BMC Evolutionary Biology, Vol 19, Iss 1, Pp 1-16 (2019)

Abstract Background Antioxidative enzymes contribute to a parasite’s ability to counteract the host’s intracellular killing mechanisms. The facultative intracellular oyster parasite, Perkinsus marinus, a sister taxon to dinoflagellates and apicom

Externí odkaz: https://doaj.org/article/e5afe035f03448928d13f426f23600ff

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Akademický článek

Biochemical Characterization of Oyster and Clam Galectins: Selective Recognition of Carbohydrate Ligands on Host Hemocytes and Perkinsus Parasites

Autor: Gerardo R. Vasta, Chiguang Feng, Satoshi Tasumi, Kelsey Abernathy, Mario A. Bianchet, Iain B. H. Wilson, Katharina Paschinger, Lai-Xi Wang, Muddasar Iqbal, Anita Ghosh, Mohammed N. Amin, Brina Smith, Sean Brown, Aren Vista

Publikováno v: Frontiers in Chemistry, Vol 8 (2020)

Both vertebrates and invertebrates display active innate immune mechanisms for defense against microbial infection, including diversified repertoires of soluble and cell-associated lectins that can effect recognition and binding to potential pathogen

Externí odkaz: https://doaj.org/article/23171c6edcb546b487ea43f576552a6d

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Akademický článek

Pregnancy Galectinology: Insights Into a Complex Network of Glycan Binding Proteins

Autor: Sandra M. Blois, Gabriela Dveksler, Gerardo R. Vasta, Nancy Freitag, Véronique Blanchard, Gabriela Barrientos

Publikováno v: Frontiers in Immunology, Vol 10 (2019)

Galectins are a phylogenetically conserved family of soluble β-galactoside binding proteins, consisting of 15 different types, each with a specific function. Galectins contribute to placentation by regulating trophoblast development, migration, and

Externí odkaz: https://doaj.org/article/256b13cf315740d09dda9c241a453167

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Animal Lectins: Structure and Function

Autor: Gerardo R. Vasta

Publikováno v: Encyclopedia of Cell Biology ISBN: 9780128216248

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c1235e6b878860fd98657b2d5fe88d61
https://doi.org/10.1016/b978-0-12-821618-7.00090-0

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Akademický článek

F-Type Lectins: A Highly Diversified Family of Fucose-Binding Proteins with a Unique Sequence Motif and Structural Fold, Involved in Self/Non-Self-Recognition

Autor: Gerardo R. Vasta, L. Mario Amzel, Mario A. Bianchet, Matteo Cammarata, Chiguang Feng, Keiko Saito

Publikováno v: Frontiers in Immunology, Vol 8 (2017)

The F-type lectin (FTL) family is one of the most recent to be identified and structurally characterized. Members of the FTL family are characterized by a fucose recognition domain [F-type lectin domain (FTLD)] that displays a novel jellyroll fold (�

Externí odkaz: https://doaj.org/article/087a4696c61f4ac693b8eda8772e7d1f

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Akademický článek

Binding of a C-type lectin's coiled-coil domain to the Domeless receptor directly activates the JAK/STAT pathway in the shrimp immune response to bacterial infection.

Autor: Jie-Jie Sun, Jiang-Feng Lan, Xiao-Fan Zhao, Gerardo R Vasta, Jin-Xing Wang

Publikováno v: PLoS Pathogens, Vol 13, Iss 9, p e1006626 (2017)

C-type lectins (CTLs) are characterized by the presence of a C-type carbohydrate recognition domain (CTLD) that by recognizing microbial glycans, is responsible for their roles as pattern recognition receptors in the immune response to bacterial infe

Externí odkaz: https://doaj.org/article/48b48c12f9e14ea2af8a13b4e7680697

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Synthesis, binding affinity, and inhibitory capacity of cyclodextrin-based multivalent glycan ligands for human galectin-3

Autor: Chong Ou, Chao Li, Chiguang Feng, Xin Tong, Gerardo R. Vasta, Lai-Xi Wang

Publikováno v: Bioorganicmedicinal chemistry. 72

Human galectin 3 (Gal-3) has been implicated to play important roles in different biological recognition processes such as tumor growth and cancer metastasis. High-affinity Gal-3 ligands are desirable for functional studies and as inhibitors for pote

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::425784d7051f6df11bf4374c0c8a7d7a
https://pubmed.ncbi.nlm.nih.gov/36108470

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Editorial

Autor: Iván Martínez-Duncker, Fabrizio Chiodo, Héctor M. Mora-Montes, Gerardo R. Vasta

Publikováno v: Frontiers in Microbiology, 13:921436. Frontiers Media S.A.
Martínez-Duncker, I, Chiodo, F, Mora-Montes, H C M & Vasta, G R 2022, ' Editorial : The Role of Glycans in Infectious Disease ', Frontiers in Microbiology, vol. 13, 921436 . https://doi.org/10.3389/fmicb.2022.921436

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9474915481c87a89e9c4f9fc17959f5b
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85131301789&origin=inward

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In Structural Glycobiology, Deuterium provides the Details

Autor: L. Mario Amzel, Gerardo R. Vasta

Publikováno v: Structure (London, England : 1993). 29(9)

In this issue of Structure, Gadjos et al. (2021b) determine the structure of a bacterial lectin in complex with L-fucose by neutron diffraction of both perdeuterated protein and carbohydrate ligand. The structure provides insight into lectin-ligand i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6d6430e380632631b6f8889806a0646
https://pubmed.ncbi.nlm.nih.gov/33765407

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