Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Gerardo Ongari"'
Autor:
Matteo Gastaldi, Diego Franciotta, Mario Cirillo, Sara Prioni, Micol Avenali, Fabrizio Esposito, Chiara Reale, Valentina Leta, Enza Maria Valente, Anna Pichiecchio, Barbara Garavaglia, Roberto Eleopra, Marina Grisoli, Roberto Cilia, Luigi Romito, Maria Grazia Bruzzone, Alessandro Tessitore, Ilaria Palmieri, Giada Cuconato, Fabiana Colucci, Pierfrancesco Mitrotti, Rosita De Micco, Marco Fusar Poli, Silvia Cerri, Mario Stanziano, Ana Bacila, Valentina Franco, Cristina Ghezzi, Antonio Emanuele Elia, Grazia Devigili, Nico Golfrè Andreasi, Federico Cazzaniga, Caterina Galandra, Giancarlo Germani, Gerardo Ongari, Marta Picascia, Mattia Verri, Federica Di Nardo, Simone Aloisio, Mattia Siciliano, Paolo Amami, Sylvie Piacentini, Fabio Moda
Publikováno v:
BMJ Neurology Open, Vol 5, Iss 2 (2023)
Background Heterozygous mutations in the GBA gene, encoding the lysosomal enzyme β-glucocerebrosidase (GCase), are the most frequent genetic risk factor for Parkinson’s disease (PD). GBA-related PD (GBA-PD) patients have higher risk of dementia an
Externí odkaz:
https://doaj.org/article/f4439946eac245c38832074e55e2c953
Autor:
Valentina Serpieri, Tommaso Biagini, Concetta Mazzotta, Rosa Pasquariello, Anna Rubegni, Filippo Santorelli, Gerardo Ongari, Silvia Cerri, Tommaso Mazza, Roberta Battini, Enza Maria Valente
Publikováno v:
Applied Sciences, Vol 11, Iss 2, p 748 (2021)
Background: Peptidase mitochondrial processing alpha (PMPCA) biallelic mutations cause a spectrum of disorders ranging from severe progressive multisystemic mitochondrial encephalopathy to a milder non-progressive cerebellar ataxia with or without in
Externí odkaz:
https://doaj.org/article/b526d64388db4a0fa92dffbe94a18fc5
Autor:
Gerardo Ongari
This protocol details methods for the isolation of peripheral blood mononuclear cells (PBMCs) from Whole Blood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0dde13cbd54cd98e53da3477f39d0a1c
https://doi.org/10.17504/protocols.io.j8nlkwbm6l5r/v1
https://doi.org/10.17504/protocols.io.j8nlkwbm6l5r/v1
Autor:
Cristina Tassorelli, Claudio Pacchetti, Silvia Cerri, Fabio Blandini, Enza Maria Valente, Micol Avenali, Gerardo Ongari, Cristina Ghezzi
Publikováno v:
Movement Disorders
Background GBA mutations are the commonest genetic risk factor for Parkinson's disease (PD) and also impact disease progression. Objective The objective of this study was to define a biochemical profile that could distinguish GBA-PD from non-mutated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf1bccaae58658b102afebf658e04eeb
https://doi.org/10.1002/mds.28496
https://doi.org/10.1002/mds.28496
Autor:
Miriam Francavilla, Fabio Blandini, Cristina Ghezzi, Claudio Giuliano, Nora Rossini, Silvia Cerri, Alessandro Petese, Gerardo Ongari
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 16
International Journal of Molecular Sciences, Vol 22, Iss 8920, p 8920 (2021)
Volume 22
Issue 16
International Journal of Molecular Sciences, Vol 22, Iss 8920, p 8920 (2021)
Parkinson’s disease (PD) is a neurodegenerative disorder characterized by the loss of dopaminergic neurons in the Substantia Nigra pars compacta, leading to classical PD motor symptoms. Current therapies are purely symptomatic and do not modify dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d432afbd4dc384c125caf4423f9cc890
https://pubmed.ncbi.nlm.nih.gov/34445626
https://pubmed.ncbi.nlm.nih.gov/34445626
Autor:
Micol Avenali, Gerardo Ongari, Stefania Croce, Cristina Ghezzi, Silvia Cerri, Donato A. Di Monte, Fabio Blandini, Roberta Zangaglia, Enza Maria Valente
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 2215, p 2215 (2021)
International journal of molecular sciences 22(4), 2215 (2021). doi:10.3390/ijms22042215
International Journal of Molecular Sciences
Volume 22
Issue 4
International journal of molecular sciences 22(4), 2215 (2021). doi:10.3390/ijms22042215
International Journal of Molecular Sciences
Volume 22
Issue 4
Heterozygous mutations in the GBA gene, encoding the lysosomal enzyme glucocerebrosidase (GCase), are the strongest known genetic risk factor for Parkinson’s disease (PD). The molecular mechanisms underlying the increased PD risk and the variable p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d9f135670233cc83ce5569d9444f633
https://www.mdpi.com/1422-0067/22/4/2215
https://www.mdpi.com/1422-0067/22/4/2215
Autor:
Enza Maria Valente, Roberta Battini, Concetta Mazzotta, Gerardo Ongari, Anna Rubegni, Valentina Serpieri, Silvia Cerri, Tommaso Mazza, Rosa Pasquariello, Tommaso Biagini, Filippo M. Santorelli
Publikováno v:
Applied Sciences, Vol 11, Iss 748, p 748 (2021)
Background: Peptidase mitochondrial processing alpha (PMPCA) biallelic mutations cause a spectrum of disorders ranging from severe progressive multisystemic mitochondrial encephalopathy to a milder non-progressive cerebellar ataxia with or without in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd53044a67aca9c834cc721e61914e5c
http://hdl.handle.net/11568/1115883
http://hdl.handle.net/11568/1115883