Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Gerardo A. Mirkin"'
Autor:
Azul V. Pieralisi, Ágata C. Cevey, Federico N. Penas, Nilda Prado, Ana Mori, Mónica Gili, Gerardo A. Mirkin, Juan Gagliardi, Nora B. Goren
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2022)
Chronic Chagas disease cardiomyopathy (CCC) is the most important clinical manifestation of infection with Trypanosma cruzi (T. cruzi) due to its frequency and effects on morbidity and mortality. Peripheral blood mononuclear cells (PBMC) infiltrate t
Externí odkaz:
https://doaj.org/article/b37c26a35ff94c1c822003ac05280bdf
Autor:
Ágata C. Cevey, Paula D. Mascolo, Federico N. Penas, Azul V. Pieralisi, Aldana S. Sequeyra, Gerardo A. Mirkin, Nora B. Goren
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Benznidazole (Bzl), the drug of choice in many countries for the treatment of Chagas disease, leads to parasite clearance in the early stages of infection and contributes to immunomodulation. In addition to its parasiticidal effect, Bzl inhibits the
Externí odkaz:
https://doaj.org/article/a448a705e0d847578212886c8a173008
Autor:
Jimena Rada, Martín Donato, Federico N. Penas, Catalina Alba Soto, Ágata C. Cevey, Azul V. Pieralisi, Ricardo Gelpi, Gerardo A. Mirkin, Nora B. Goren
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
IL-10 is an anti-inflammatory cytokine that plays a significant role in the modulation of the immune response in many pathological conditions, including infectious diseases. Infection with Trypanosoma cruzi (T. cruzi), the etiological agent of Chagas
Externí odkaz:
https://doaj.org/article/789a7dcbe9e04d4498aac08b8da6b2f8
Autor:
Federico Nicolás Penas, Davide Carta, Ágata Carolina Cevey, María Jimena Rada, Azul Victoria Pieralisi, María Grazia Ferlin, María Elena Sales, Gerardo A. Mirkin, Nora Beatriz Goren
Publikováno v:
Frontiers in Immunology, Vol 10 (2020)
Chagas disease is caused by Trypanosoma cruzi infection and represents an important public health concern in Latin America. Macrophages are one of the main infiltrating leukocytes in response to infection. Parasite persistence could trigger a sustain
Externí odkaz:
https://doaj.org/article/c762bd450ddd4e6991ccea302c57b243
Autor:
Ágata C. Cevey, Gerardo A. Mirkin, Martín Donato, María J. Rada, Federico N. Penas, Ricardo J. Gelpi, Nora B. Goren
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 7, Iss 3, Pp 378-387 (2017)
Trypanosoma cruzi induces serious cardiac alterations during the chronic infection. Intense inflammatory response observed from the beginning of infection, is critical for the control of parasite proliferation and evolution of Chagas disease. Peroxis
Externí odkaz:
https://doaj.org/article/2098241fed4f460e822eb3c21cc598c1
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Anti-parasitic treatment for Chagas disease mainly relies on benznidazole, which is virtually the only drug available in the market. Besides its anti-parasitic effects, benznidazole has anti-inflammatory properties. In this work we studied the mechan
Externí odkaz:
https://doaj.org/article/5b549f72290a47658f292520769d03de
Publikováno v:
PPAR Research, Vol 2012 (2012)
Chagas disease, which is caused by Trypanosoma cruzi (T. cruzi), remains a substantial public health concern and an important cause of morbidity and mortality in Latin America. T. cruzi infection causes an intense inflammatory response in diverse tis
Externí odkaz:
https://doaj.org/article/94e9d102929e4dada87ef7b8e0bca28f
Autor:
Ágata Carolina Cevey, Azul Victoria Pieralisi, Martín Donato, Jimena Rada, Ricardo Jorge Gelpi, Gerardo Ariel Mirkin, Nora Beatriz Goren, Federico Nicolás Penas
Publikováno v:
ACS Infectious Diseases. 9:213-220
Publikováno v:
Experimental Parasitology. 170:100-108
Trypanosoma cruzi, the etiological agent of Chagas´ disease, causes an intense inflammatory response in several tissues, including the liver. Since this organ is central to metabolism, its infection may be reflected in the outcome of the disease. 15
Autor:
Catalina D. Alba Soto, Ágata Carolina Cevey, Federico Nicolás Penas, Nora Goren, Gerardo A. Mirkin
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Frontiers in Immunology
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Anti-parasitic treatment for Chagas disease mainly relies on benznidazole, which is virtually the only drug available in the market. Besides its anti-parasitic effects, benznidazole has anti-inflammatory properties. In this work we studied the mechan