Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Gerardo A Morfini"'
Autor:
Emiliano Zamponi, Fiamma Buratti, Gabriel Cataldi, Hector Hugo Caicedo, Yuyu Song, Lisa M Jungbauer, Mary J LaDu, Mariano Bisbal, Alfredo Lorenzo, Jiyan Ma, Pablo R Helguera, Gerardo A Morfini, Scott T Brady, Gustavo F Pigino
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0188340 (2017)
Prion diseases include a number of progressive neuropathies involving conformational changes in cellular prion protein (PrPc) that may be fatal sporadic, familial or infectious. Pathological evidence indicated that neurons affected in prion diseases
Externí odkaz:
https://doaj.org/article/9ec8a9f6cfde4b63934a882da4ebbb3c
Autor:
Gerardo A Morfini, Daryl A Bosco, Hannah Brown, Rodolfo Gatto, Agnieszka Kaminska, Yuyu Song, Linda Molla, Lisa Baker, M Natalia Marangoni, Sarah Berth, Ehsan Tavassoli, Carolina Bagnato, Ashutosh Tiwari, Lawrence J Hayward, Gustavo F Pigino, D Martin Watterson, Chun-Fang Huang, Gary Banker, Robert H Brown, Scott T Brady
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65235 (2013)
Dying-back degeneration of motor neuron axons represents an established feature of familial amyotrophic lateral sclerosis (FALS) associated with superoxide dismutase 1 (SOD1) mutations, but axon-autonomous effects of pathogenic SOD1 remained undefine
Externí odkaz:
https://doaj.org/article/c19ff8f0c04447fd912d1b2f9f9ca560
Publikováno v:
Frontiers in Bioscience. 14:5239
In general, virus infections of the brain are rather rare in the immune competent host. However, neurotropic viruses have developed mechanisms to exploit weaknesses in immunological defense mechanisms that eventually allow them to reach and infect CN
Autor:
Rebecca L. Mueller, Benjamin Combs, Mohammed M. Alhadidy, Scott T. Brady, Gerardo A. Morfini, Nicholas M. Kanaan
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Over four decades ago, in vitro experiments showed that tau protein interacts with and stabilizes microtubules in a phosphorylation-dependent manner. This observation fueled the widespread hypotheses that these properties extend to living neurons and
Externí odkaz:
https://doaj.org/article/563b922d88b1451abc0469995783e28e
Autor:
Scott T. Brady, Gerardo A. Morfini
Publikováno v:
Neurobiology of Disease, Vol 105, Iss , Pp 273-282 (2017)
Neurons affected in a wide variety of unrelated adult-onset neurodegenerative diseases (AONDs) typically exhibit a “dying back” pattern of degeneration, which is characterized by early deficits in synaptic function and neuritic pathology long bef
Externí odkaz:
https://doaj.org/article/3abac85feebd4736a24e226ad279eed9