Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Gerardo A De Blas"'
Autor:
Cintia C. Vaquer, Laila Suhaiman, Martín A. Pavarotti, Rodolfo J. Arias, Anahí B. Pacheco Guiñazú, Gerardo A. De Blas, Silvia A. Belmonte
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Before fertilization, spermatozoa must undergo calcium-regulated acrosome exocytosis in response to physiological stimuli such as progesterone and zona pellucida. Our laboratory has elucidated the signaling cascades accomplished by different sphingol
Externí odkaz:
https://doaj.org/article/1373477c751c42f88bc0361a4d62e431
Autor:
Ruiming Zhao, Hui Dai, Rodolfo J. Arias, Gerardo A. De Blas, Gerardo Orta, Martín A. Pavarotti, Rong Shen, Eduardo Perozo, Luis S. Mayorga, Alberto Darszon, Steve A. N. Goldstein
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
The human voltage-gated proton channel (hHv1) maintains intracellular pH and membrane potential in sperm and neutrophils. Here, the authors show that albumin activates hHv1, by binding to the channel voltage sensor domains to enhance open probability
Externí odkaz:
https://doaj.org/article/c46008eddc1543f7b537b4b7900693ee
Publikováno v:
EURASIP Journal on Wireless Communications and Networking, Vol 2019, Iss 1, Pp 1-14 (2019)
Abstract Future large-scale network function virtualization (NFV) environments will be based on hundreds or even thousands of NFV infrastructure installations, the so called points of presence (PoP). All their resources and the services deployed on t
Externí odkaz:
https://doaj.org/article/380008617a83485c970a54bdc87aca3e
Male Decapacitation Factor SPINK3 Blocks Membrane Hyperpolarization and Calcium Entry in Mouse Sperm
Autor:
Lucia Zalazar, Cintia Stival, Anabella R. Nicolli, Gerardo A. De Blas, Dario Krapf, Andreina Cesari
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Mammalian sperm acquire ability to fertilize through a process called capacitation, occurring after ejaculation and regulated by both female molecules and male decapacitation factors. Bicarbonate and calcium present in the female reproductive tract t
Externí odkaz:
https://doaj.org/article/714843b47f8642fda99e1d831200cd4f
Autor:
Sheini Ruturi Sánchez González, Esperanza Mata Martínez, Jorge Arturo Torres Juárez, Rodolfo José Arias, Gerardo Andrés De Blas, Ana Alicia Sánchez Tusie
Publikováno v:
Andrology. 11:134-142
Publikováno v:
Biology Open, Vol 7, Iss 12 (2018)
Oocyte in vitro maturation does not entirely support all the nuclear and cytoplasmic changes that occur physiologically, and it is poorly understood whether in vitro maturation affects the competence of cortical granules to secrete their content duri
Externí odkaz:
https://doaj.org/article/a0cb29eacdc54c61a0370cbc099b5da9
Autor:
Sheini Ruturi, Sánchez González, Esperanza, Mata Martínez, Jorge Arturo, Torres Juárez, Rodolfo José, Arias, Gerardo Andrés, De Blas, Ana Alicia, Sánchez Tusie
Publikováno v:
AndrologyREFERENCES. 11(1)
Stress and elevated cortisol levels have negative effects on fertility, although there is controversy about the effect of cortisol on human sperm. One study reported that hydrocortisone (HC), the synthetic form of cortisol, does not activate CatSper
Autor:
Luis S. Mayorga, Gerardo A. De Blas, Alberto Darszon, Ana A. Sánchez-Tusie, Esperanza Mata-Martínez, Claudia L. Treviño
Publikováno v:
Andrology. 9:1227-1241
Background The signaling pathways of the intracellular second messengers cAMP and Ca2+ play a crucial role in numerous physiological processes in human spermatozoa. One such process is the acrosome reaction (AR), which is necessary for spermatozoa to
Autor:
Diego M. Marzese, Gerardo A. De Blas, Emanuel M. Campoy, Maria Roque Moreno, Rodolfo J. Arias, Sofia Masuelli, Matthew P. Salomon, Maria Teresita Branham, Sebastián M Real, Michael Levin
Background: During embryogenesis, lateral symmetry is broken giving rise to Left/Right (L/R) breast tissues with distinct identity. L/R-sided breast tumors exhibit consistently-biased incidence, gene expression, and DNA methylation. We postulate that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3811fe5df8a5e8fd41d311e0cf3c03d
https://doi.org/10.21203/rs.3.rs-1020823/v1
https://doi.org/10.21203/rs.3.rs-1020823/v1
Autor:
Eduardo Perozo, Martin Alejandro Pavarotti, Gerardo A. De Blas, Gerardo Orta, Alberto Darszon, Luis S. Mayorga, Rodolfo J. Arias, Steve A.N. Goldstein, Rong Shen, Hui Dai, Ruiming Zhao
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature communications, vol 12, iss 1
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature communications, vol 12, iss 1
Human voltage-gated proton channels (hHv1) extrude protons from cells to compensate for charge and osmotic imbalances due metabolism, normalizing intracellular pH and regulating protein function. Human albumin (Alb), present at various levels through