Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Gerard R Rutteman"'
Autor:
Jacquelyn M Evans, Heidi G Parker, Gerard R Rutteman, Jocelyn Plassais, Guy C M Grinwis, Alexander C Harris, Susan E Lana, Elaine A Ostrander
Publikováno v:
PLoS Genetics, Vol 17, Iss 5, p e1009543 (2021)
Histiocytic sarcoma is an aggressive hematopoietic malignancy of mature tissue histiocytes with a poorly understood etiology in humans. A histologically and clinically similar counterpart affects flat-coated retrievers (FCRs) at unusually high freque
Externí odkaz:
https://doaj.org/article/fc74da61633c453ea21758503fc0d908
Autor:
Maja L Arendt, Malin Melin, Noriko Tonomura, Michele Koltookian, Celine Courtay-Cahen, Netty Flindall, Joyce Bass, Kim Boerkamp, Katherine Megquir, Lisa Youell, Sue Murphy, Colleen McCarthy, Cheryl London, Gerard R Rutteman, Mike Starkey, Kerstin Lindblad-Toh
Publikováno v:
PLoS Genetics, Vol 11, Iss 11, p e1005647 (2015)
Canine mast cell tumours (CMCT) are one of the most common skin tumours in dogs with a major impact on canine health. Certain breeds have a higher risk of developing mast cell tumours, suggesting that underlying predisposing germ-line genetic factors
Externí odkaz:
https://doaj.org/article/895b2898a7834518bb77388c3398301a
Autor:
Joana T de Oliveira, Cláudia Ribeiro, Rita Barros, Catarina Gomes, Augusto J de Matos, Celso A Reis, Gerard R Rutteman, Fátima Gärtner
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0134458 (2015)
The tumor microenvironment encompasses several stressful conditions for cancer cells such as hypoxia, oxidative stress and pH alterations. Galectin-3, a well-studied member of the beta-galactoside-binding animal family of lectins has been implicated
Externí odkaz:
https://doaj.org/article/8905a6e1553b4af4bcb526c5299b9f84
Autor:
Kim M Boerkamp, Frank G van Steenbeek, Louis C Penning, Marian J A Groot Koerkamp, Dik van Leenen, Manon Vos-Loohuis, Guy C M Grinwis, Gerard R Rutteman
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e98258 (2014)
Examination of gene functions in specific tumor types improves insight in tumorigenesis and helps design better treatments. Due to the rarity of histiocytic/dendritic cell sarcoma in humans, it is difficult to accrue such knowledge. Therefore, compar
Externí odkaz:
https://doaj.org/article/5953b5baa67b45e38fafc5a9485419c5
Autor:
Kim M Boerkamp, Marieke van der Kooij, Frank G van Steenbeek, Monique E van Wolferen, Marian J A Groot Koerkamp, Dik van Leenen, Guy C M Grinwis, Louis C Penning, Erik A C Wiemer, Gerard R Rutteman
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71094 (2013)
BackgroundThe determination of altered expression of genes in specific tumor types and their effect upon cellular processes may create insight in tumorigenesis and help to design better treatments. The Flatcoated retriever is a dog breed with an exce
Externí odkaz:
https://doaj.org/article/cb03fb412bee43de96f6241999709856
Autor:
Elaine A. Ostrander, Heidi G. Parker, Catherine André, Gerard R. Rutteman, Matthew Breen, Francis Galibert, Mary Lynch, Danielle M. Karyadi, Maud Rimbault, Patrick Devauchelle, Andrea Gröne, Erika M. Kwon, Jerome Abadie, John Cullen, Daniel L. Faden, Emmett V. Schmidt, Suzanne A. Erich, Edouard Cadieu, Benoit Hedan, Abigail L. Shearin
Background: Advantages offered by canine population substructure, combined with clinical presentations similar to human disorders, makes the dog an attractive system for studies of cancer genetics. Cancers that have been difficult to study in human f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2702bc74d1a03c07b6fd41f88c6ca412
https://doi.org/10.1158/1055-9965.c.6515439
https://doi.org/10.1158/1055-9965.c.6515439
Autor:
Elaine A. Ostrander, Heidi G. Parker, Catherine André, Gerard R. Rutteman, Matthew Breen, Francis Galibert, Mary Lynch, Danielle M. Karyadi, Maud Rimbault, Patrick Devauchelle, Andrea Gröne, Erika M. Kwon, Jerome Abadie, John Cullen, Daniel L. Faden, Emmett V. Schmidt, Suzanne A. Erich, Edouard Cadieu, Benoit Hedan, Abigail L. Shearin
PDF file - 493K, The MTAP-CDKN2A Locus Confers Susceptibility to Cancer in a Naturally Occurring Canine Model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb667d2cc47081b859cf6cebf5b1384b
https://doi.org/10.1158/1055-9965.22436502.v1
https://doi.org/10.1158/1055-9965.22436502.v1
Autor:
Jacquelyn M. Evans, Gerard R. Rutteman, Heidi G. Parker, Elaine A. Ostrander, Jocelyn Plassais
Publikováno v:
Cancer Research. 81:829-829
Histiocytic sarcoma is a rare, aggressive hematopoietic malignancy of mature tissue histiocytes with a poorly understood etiology in humans. A histologically and clinically similar counterpart in dogs affects two breeds at unusually high frequency, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b763f6d1bc7a2e21dc7a170630547b8e
https://doi.org/10.1158/1538-7445.am2021-829
https://doi.org/10.1158/1538-7445.am2021-829
Publikováno v:
The Veterinary Journal. 197:656-661
Chemotherapy protocols for canine lymphoma include the routine use of glucocorticoids for their lympholytic effect. However, glucocorticoids are associated with side effects (e.g. polyphagia, polyuria, and weight gain), limit the use of non-steroidal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a10fd3980031a4ef2ee6d1dcb15c2dfe
https://doi.org/10.1016/j.tvjl.2013.04.022
https://doi.org/10.1016/j.tvjl.2013.04.022
Autor:
Cláudia S. Baptista, A.J.F. Matos, Maria de Fátima Rodrigues Moutinho Gärtner, Gerard R. Rutteman
Publikováno v:
The Veterinary Journal; Vol 193
For several years, veterinary oncologists have been struggling with the prognosis of mammary tumours in dogs and cats. Translation of tumour characteristics into prognostic information is an invaluable tool for the use of the most appropriate therapi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d841c316f750566feacb67eed65d13d4
https://doi.org/10.1016/j.tvjl.2011.12.019
https://doi.org/10.1016/j.tvjl.2011.12.019