Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Gerard P. vanBerge-Henegouwen"'
Autor:
Piero Portincasa, Niels G. Venneman, Antonio Moschetta, André van den Berg, Giuseppe Palasciano, Gerard P. vanBerge-Henegouwen, Karel J. van Erpecum
Publikováno v:
Journal of Lipid Research, Vol 43, Iss 4, Pp 604-610 (2002)
Cholesterol crystallization is an essential step in gallstone formation. Although spectrophotometry and nephelometry have been used for quantitation of crystallization, potential effects of crystal size and shape have not been evaluated. We determine
Externí odkaz:
https://doaj.org/article/694d7bf721a6447796e5feee7c477042
Autor:
Antonio Moschetta, Gerard P. vanBerge-Henegouwen, Piero Portincasa, Giuseppe Palasciano, Karel J. van Erpecum
Publikováno v:
Journal of Lipid Research, Vol 42, Iss 8, Pp 1273-1281 (2001)
Cholesterol in human bile is solubilized in micelles by (relatively hydrophobic) bile salts and phosphatidylcholine (unsaturated acyl chains at sn-2 position). Hydrophilic tauroursodeoxycholate, dipalmitoyl phosphatidylcholine, and sphingomyelin all
Externí odkaz:
https://doaj.org/article/258e89419cc54b009c9d3c8ff3d49a84
Autor:
Antonio Moschetta, Gerard P. vanBerge-Henegouwen, Piero Portincasa, Giuseppe Palasciano, Albert K. Groen, Karel J. van Erpecum
Publikováno v:
Journal of Lipid Research, Vol 41, Iss 6, Pp 916-924 (2000)
Inclusion of phosphatidylcholine within bile salt micelles protects against bile salt-induced cytotoxicity. In addition to phosphatidylcholine, bile may contain significant amounts of sphingomyelin, particularly under cholestatic conditions. We compa
Externí odkaz:
https://doaj.org/article/c921589049e34637a4ae3814e3c9b0ae
Autor:
Erik R.M. Eckhardt, Bert J.M. van de Heijning, Karel J. van Erpecum, Willem Renooij, Gerard P. VanBerge-Henegouwen
Publikováno v:
Journal of Lipid Research, Vol 39, Iss 3, Pp 594-603 (1998)
The inter-mixed micellar/vesicular (non-phospholipid-associated) bile salt concentration (IMC) can be rapidly measured in model biles by centrifugal ultrafiltration, thus allowing reliable separation of vesicular and micellar cholesterol carriers by
Externí odkaz:
https://doaj.org/article/29b497d0657e4154b8f6c1104ff21b62
Autor:
Ivo A. M. J. Broeders, Niels G. Venneman, Karel J. van Erpecum, Gerard P. vanBerge-Henegouwen, Peter M. N. Y. H. Go, Yolande C.A. Keulemans, Marja A. Boermeester, Marc G. Besselink
Publikováno v:
Hepatology (Baltimore, Md.), 43(6), 1276-1283. John Wiley and Sons Ltd
Ursodeoxycholic acid (UDCA) and impaired gallbladder motility purportedly reduce biliary pain and acute cholecystitis in patients with gallstones. However, the effect of UDCA in this setting has not been studied prospectively. This issue is important
Publikováno v:
Current Drug Targets - Immune, Endocrine & Metabolic Disorders. 5:185-191
Gallstone disease in the Western world has an estimated prevalence of 10-15% and more than 75% are cholesterol-enriched gallstones. Defective gallbladder motility has been identified as an important pathogenic factor for cholesterol gallstone disease
Autor:
Willem Renooij, Gerard P. vanBerge-Henegouwen, Ivo A. M. J. Broeders, Niels G. Venneman, Peter M. N. Y. H. Go, Karel J. van Erpecum, Jens F. Rehfeld
Publikováno v:
Hepatology. 41:738-746
Acute pancreatitis is a severe complication of gallstones with considerable mortality. We sought to explore the potential risk factors for biliary pancreatitis. We compared postprandial gallbladder motility (via ultrasonography) and, after subsequent
Publikováno v:
Scopus-Elsevier
The gallbladder epithelium and smooth muscle layer are exposed to concentrated biliary solutes, including cholesterol and potentially toxic hydrophobic bile salts, which are able to influence muscle contraction. Physiologically, gallbladder tone is r
Autor:
A. K. Groen, Piero Portincasa, Gerard P. vanBerge-Henegouwen, Astrid Kosters, Niels G. Venneman, K.J. van Erpecum
Publikováno v:
Scandinavian journal of gastroenterology, 39(Suppl. 241), 60-69. Informa Healthcare
In the formation of cholesterol gallstones, cholesterol hypersecretion into bile causing cholesterol supersaturation and crystallization appears to be the primary factor, with disturbed gallbladder and intestinal motility as secondary factors. Althou
Autor:
Gerard P. vanBerge Henegouwen, G. Boudewijn C. Vasbinder, André J.P.M. Smout, Marc F. J. Stolk, Me-Yun Ke, Rick J. A. Jebbink, Louis M. A. Akkermans
Publikováno v:
American journal of gastroenterology, 98(1), 66-71. Springer Nature
OBJECTIVES: In previous manometric studies, we observed that micturition was associated with phase III of the migrating motor complex. The present study aimed to objectify this possible relationship and to examine whether modulation of micturition fr