Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Gerard P. McGregor"'
Autor:
Gerard P. McGregor
Publikováno v:
Advances in Therapy. 33:186-198
Clopacin® (Acino Pharma AG) is a proprietary, besylate salt and lactose-free formulation of the widely-used anti-platelet treatment, clopidogrel. This study aimed to evaluate the bioequivalence of Clopacin® with the originator as reference drug, us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bb2c2154804291f578ac90ee737ff06
https://doi.org/10.1007/s12325-016-0290-0
https://doi.org/10.1007/s12325-016-0290-0
Publikováno v:
Phytotherapy Research. 26:806-811
Harpagophytum procumbens (Hp) is often used in the supportive treatment of inflammatory and degenerative diseases of the skeletal system. Although the clinical efficacy in osteoarthritis has been demonstrated in clinical trials, the molecular target(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::306cf5980f0f19a1a5ca92024a3c4c61
https://doi.org/10.1002/ptr.3636
https://doi.org/10.1002/ptr.3636
Publikováno v:
Toxicology in Vitro. 25:21-27
The effect of a standardised dry extract from Silybum marianum (HEPAR-PASC®) on the enzyme kinetics of cytochrome-P450 isoenzymes (CYP) was investigated with primary human hepatocytes and human liver microsomes in order to assess the potential for d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::379a94a44786b84729b6ad6833cbd2a3
https://doi.org/10.1016/j.tiv.2010.09.001
https://doi.org/10.1016/j.tiv.2010.09.001
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 91:522-525
Context: By enhancing energy expenditure and suppressing appetite, melanocortin peptides derived from proopiomelanocortin play a primary role in the hypothalamic regulation of body weight. In a recent study in normal-weight adults, the 6-wk intranasa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47a7ada3a515c07e022f471e0b3531cc
https://doi.org/10.1210/jc.2005-0906
https://doi.org/10.1210/jc.2005-0906
Autor:
Andrea Wartenberg, George Lewith, Bernd L. Fiebich, Tankred Wegener, Sarah Brien, Gerard P. McGregor
Publikováno v:
Phytochemistry Reviews. 4:47-53
Extracts of the secondary roots of the southern African plant, Devil’s Claw (Harpagophytum procumbens) provide a herbal drug with a variety of traditional indications. One area of its use that has become very popular in recent years is in the treat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52eca6fb6a4f6d78b3c8ae3463fba10a
https://doi.org/10.1007/s11101-004-2374-8
https://doi.org/10.1007/s11101-004-2374-8
Autor:
Bertram Wiedenmann, Johannes J. Tebbe, Rudolf Arnold, Ivo R. van der Voort, Birgit Wollenberg, Burghard F. Klapp, Hubert Mönnikes, Wibke Alt, Gerard P. McGregor, Ingeborg Heymann-Mönnikes
Publikováno v:
Digestion. 71:111-123
Background and Aims: In functional dyspepsia (FD) decreased perception levels can be shown on gastric distension. Substance P (SP) and calcitonin gene-related peptide (CGRP) are involved in the sensitization of afferent neuronal pathways due to chron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::419233b0187ee61b554bfd80a310ecce
https://doi.org/10.1159/000084625
https://doi.org/10.1159/000084625
Autor:
Marek Lommatzsch, Ulrich Neuhaus-Steinmetz, Thomas Glaab, Harald Renz, Axel Fischer, Gerard P. McGregor, Armin Braun, David Quarcoo
Publikováno v:
British Journal of Pharmacology. 141:431-440
Brain-derived neurotrophic factor (BDNF) is a candidate molecule for mediating functional neuronal changes in allergic bronchial asthma. Recently, enhanced production of BDNF during allergic airway inflammation caused by infiltrating T-cells and macr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22992dfa653494a7f927e562a7aed507
https://doi.org/10.1038/sj.bjp.0705638
https://doi.org/10.1038/sj.bjp.0705638
Autor:
Wolfgang Kummer, Magdalena Chottova Dvorakova, Stefanie Hagner, Jana Slavikova, Gerard P. McGregor, Rainer Viktor Haberberger
Publikováno v:
Anatomy and Embryology. 207:307-315
During ontogenesis the 52 amino acid peptide adrenomedullin is first expressed in the heart and it is essential for normal cardiovascular development. Recent work suggests that most adrenomedullin effects are conveyed via the calcitonin receptor-like
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52139638cfe79eb0a8cf833a84619de5
https://doi.org/10.1007/s00429-003-0344-3
https://doi.org/10.1007/s00429-003-0344-3
Publikováno v:
Journal of Neurochemistry. 85:882-888
Tachykinins play an important role in peripheral inflammatory diseases and disorders of the CNS. Most members of the tachykinin family are generated by alternative post-transcriptional splicing of the prepro-tachykinin (PPT) A gene. Here, we examined
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f590acb361bdd2cf8ccbbb75d2ebe13a
https://doi.org/10.1046/j.1471-4159.2003.01720.x
https://doi.org/10.1046/j.1471-4159.2003.01720.x
Autor:
Gerard P. McGregor, Christian Peiser, David A. Groneberg, Rudolf E. Lang, Jochen Springer, Axel Fischer
Publikováno v:
Neuroscience Letters. 320:41-44
Recent studies suggest that in addition to adipocytes the chief cells of the gastric fundic mucosa are a site of leptin production. In order to assess the possible role of vagal afferent neurons in transmitting leptin signals from the stomach to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4164741d2d4a5e9ebd782d9d01cf531e
https://doi.org/10.1016/s0304-3940(02)00023-x
https://doi.org/10.1016/s0304-3940(02)00023-x